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New findings show importance of physical forces in tumor metastasis

A malignant tumor is characterized by its ability to spread around its surroundings. To do so, tumor cells stick to the surrounding tissue (mainly collagen) and use forces to propel.

26 Sep 2018

Understanding mosquitoes’ mating behavior is key for developing vector control strategies

The ears of male mosquitoes amplify the sound of an approaching female using a self-generated phantom tone that mimics the female's wingbeats, which increases the ear's acoustic input by a factor of up to 45,000, finds a new UCL-led study.

26 Sep 2018

Researchers discover novel targeting agents to prevent cancer metastasis

Recently, a research team led by Maurizio Pellecchia at the University of California, Riverside, discovered a way for chemotherapy drug paclitaxel to target migrating, or circulating, cancer cells, which are responsible for the development of tumor metastases.

26 Sep 2018

Mesoblast’s MPC therapy for children featured at symposium for congenital heart disease

Mesoblast Limited today announced that Mesoblast's proprietary allogeneic mesenchymal precursor cell heart failure product candidate MPC-150-IM for use in children with hypoplastic left heart syndrome was featured at the First Cardiac Regenerative Symposium for Congenital Heart Disease in Baltimore, Maryland on the weekend.

26 Sep 2018

Brigatinib drug may offer first-line treatment option for ALK-positive NSCLC

Results of a 275-patient, multi-national phase III clinical trial known as ALTA-1L published today in the New England Journal of Medicine and presented concurrently in the press program at the International Association for the Study of Lung Cancer (IASLC) World Conference on Lung Cancer 2018 argue for brigatinib as a first-line treatment option for advanced ALK-positive non-small cell lung cancer.

26 Sep 2018

VRK1 protein may enable cancer cells to colonize new areas of the body during metastasis

Sometimes negative results can point researchers in the right direction. In results published in PLOS ONE on September 4, 2018, scientists at the Medical University of South Carolina examined a protein called vaccinia-related kinase 1 that they hypothesized was important for metastasis. They found that, rather than causing cancer cells to migrate and invade, VRK1 over-expression had the opposite effect.

26 Sep 2018

Pathogenic bacteria hibernate to escape antibiotic treatments

BACTERIA University of Copenhagen researchers have discovered a surprising tactic of pathogenic bacteria when being attacked by antibiotics: hibernation.

26 Sep 2018

Study reveals structure of potential drug target in neurological conditions

Researchers at Van Andel Research Institute (VARI) have revealed the atomic-level structure of a protein that could serve as a promising new drug target for the treatment of neurological conditions such as bipolar disorder and Alzheimer’s disease.

25 Sep 2018

DFG establishes nine new Research Units

The Deutsche Forschungsgemeinschaft is establishing nine new Research Units, following a decision by the Senate and the Joint Committee in Bonn.

25 Sep 2018

New technology helps detect smallest magnetic fields produced in neuronal networks

The scientists in Freiburg will produce and optimize NV centers in diamond in order to achieve highly sensitive magnet field detectors working at room temperature, and by those means develop the world's first laser threshold magnetometer.

25 Sep 2018

Genervon reports new findings that drug candidate GM6 attenuates Alzheimer's disease in mice model

Following the closure of several research programs for Alzheimer's disease, in early 2018 the FDA issued a release entitled "Draft Guidance for Industry: Early Alzheimer's Disease: Developing Drugs for Treatment." Encouraged by the proposed changes in the new guidance, Genervon's research team reported new findings that its drug candidate GM6 attenuates Alzheimer's disease in an early AD transgenic APP mice model.

25 Sep 2018

Tomocube introduces new holotomography microscope for live cell imaging

A novel optical microscope utilizing diffraction tomography to generate 3D holographic images of unlabelled live cells is now available from Tomocube. Called HT-1, the new microscope delivers quantitative nanoscale, real-time, dynamic images of individual living cells quickly and simply without any sample preparation.

From Tomocube Inc. 25 Sep 2018

Researchers develop molecule that makes cancer cells sensitive to radiotherapy

Researchers from Karolinska Institutet and Kancera AB have developed a molecule that makes cancer cells sensitive to radiotherapy. In a study published in Nature Communications, the researchers describe a new way to block cancer cells' ability to repair their DNA and thus stop the survival of cancer cells.

25 Sep 2018

Novel approach allows researchers to define how cells in the retina respond to diabetes

Researchers will for the first time be defining how every cell type within the retina responds to diabetes, in a study announced by eye research charity Fight for Sight during National Eye Health Week 2018.

25 Sep 2018

Researchers find molecule that halts, reverts neurodegeneration caused by Parkinson's disease

The small SynuClean-D molecule interrupts the formation of the alpha-synuclein amyloid fibers responsible for the onset of Parkinson's disease, and reverts the neurodegeneration caused by the disease.

25 Sep 2018

Researchers develop way to measure different types of fear of falling in patients with Parkinson’s

Parkinson's disease, a progressive nervous system disorder that affects movement, causes one of the highest risks of falling among all neurological conditions. Due to this, many patients develop a fear of falling, even if they have never fallen.

25 Sep 2018

Toxicological evaluation and dosimetry estimation of potential PET radiotracer

The SR101 N-(3-[18F]Fluoropropyl) sulfonamide ([18F]SRF101) is a Sulforhodamine 101 derivative that was previously synthesized by our group.

25 Sep 2018

UC Davis researchers take critical step in developing more effective Salmonella vaccine

UC Davis researchers announce in the Proceedings of the National Academy of Sciences this week a breakthrough in understanding which cells afford optimal protection against Salmonella infection--a critical step in developing a more effective and safe vaccine against a bacterium that annually kills an estimated one million people worldwide.

25 Sep 2018

Study: Women with non-small cell lung cancers live longer than their male counterparts

Women diagnosed with non-small cell lung cancers live longer than their male counterparts, according to results of a SWOG study presented today by Kathy Albain, MD, the Huizenga Family Endowed Chair in Oncology Research at Loyola University Chicago Stritch School of Medicine, at the International Association for the Study of Lung Cancer's 19th World Conference on Lung Cancer in Toronto, Ontario, Canada.

25 Sep 2018

Human-oriented perspective needed to better understand Parkinson's disease

Analysis published in Drug Discovery Today reveals the gap between animal models of Parkinson's disease and our understanding of the neurodegenerative processes underlying the disease, and calls for the implementation of modern, human biology-based technologies to better understand pathological processes and improve treatment outcome.

25 Sep 2018

Cell News and Research

New findings show importance of physical forces in tumor metastasis

Understanding mosquitoes’ mating behavior is key for developing vector control strategies

Researchers discover novel targeting agents to prevent cancer metastasis

Mesoblast’s MPC therapy for children featured at symposium for congenital heart disease

Brigatinib drug may offer first-line treatment option for ALK-positive NSCLC

VRK1 protein may enable cancer cells to colonize new areas of the body during metastasis

Pathogenic bacteria hibernate to escape antibiotic treatments

Study reveals structure of potential drug target in neurological conditions

DFG establishes nine new Research Units

New technology helps detect smallest magnetic fields produced in neuronal networks

Genervon reports new findings that drug candidate GM6 attenuates Alzheimer's disease in mice model

Tomocube introduces new holotomography microscope for live cell imaging

Researchers develop molecule that makes cancer cells sensitive to radiotherapy

Novel approach allows researchers to define how cells in the retina respond to diabetes

Researchers find molecule that halts, reverts neurodegeneration caused by Parkinson's disease

Researchers develop way to measure different types of fear of falling in patients with Parkinson’s

Toxicological evaluation and dosimetry estimation of potential PET radiotracer

UC Davis researchers take critical step in developing more effective Salmonella vaccine

Study: Women with non-small cell lung cancers live longer than their male counterparts

Human-oriented perspective needed to better understand Parkinson's disease

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