Laboratory News and Research

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Designer molecules that combine metals such as copper with natural organic materials could treat diseases in the body

That's the finding of chemists at Ohio State University, who have successfully tested such molecules against portions of HIV and Hepatitis C virus RNA in the laboratory. They've also created molecules that act like ACE, or angiotensin-converting enzyme, inhibitors - drugs that are used to lower blood pressure.

30 Aug 2005

Step towards understanding cell mutations that cause a variety of human diseases

A step towards understanding cell mutations that cause a variety of human diseases, particularly in children - including that which brings about premature aging and early death - has been taken by researchers at the Hebrew University of Jerusalem Silberman Institute of Life Sciences and the John Hopkins University School of Medicine.

30 Aug 2005

Toxic flame retardants known as PBDEs are becoming a major environmental health concern

An analysis of persistent chemicals in the breastmilk of Pacific Northwest mothers, released today at an international scientific conference in Toronto, “Dioxin 2005,” found that levels of the toxic flame retardants PBDEs may be overtaking those of PCBs, an industrial chemical banned in the late 1970s.

30 Aug 2005

Asian bird flu expert joins Murdoch University

Murdoch University's School of Veterinary and Biomedical Sciences have appointed Dr Trevor Ellis, an expert in Asian Bird flu, SARS and Foot and Mouth Disease.

30 Aug 2005

Good old fashioned soap and water the answer for "superbug"

Superbugs are bacteria that have mutated to become resistant to common antibiotics which are no longer any use against them.

30 Aug 2005

New treatment can zap cancer cells and avoid healthy tissue

Australian researchers say they have developed a cancer treatment which can identify and kill individual cancer cells.

30 Aug 2005

Anti-cancer antibodies produced in chickens

A team of researchers have produced the first fully functional, human sequence monoclonal antibodies (mAbs) in chickens.

29 Aug 2005

Blocking Hutchinson-Gilford progeria syndrome (HGPS) with anticancer drugs

A class of anticancer drugs currently being evaluated in phase 3 clinical trials may also be an effective treatment for Hutchinson-Gilford progeria syndrome (HGPS), a fatal genetic disorder that causes premature aging.

29 Aug 2005

Three-dimensional molecular structure of a promising malaria-vaccine component

An international team of scientists that includes a researcher from the U.S. Department of Energy's Brookhaven National Laboratory has determined the three-dimensional molecular structure of a promising malaria-vaccine component.

29 Aug 2005

Drugs known as farnesyltransferase inhibitors (FTIs) may hold promise for premature aging disorder

In a surprising development, a research team led by the National Human Genome Research Institute (NHGRI), has found that a class of experimental anti-cancer drugs also shows promise in laboratory studies for treating a fatal genetic disorder that causes premature aging.

29 Aug 2005

Relative of the celebrated COX-2 inhibitor celecoxib is tough tumor fighter

A close structural relative of the celebrated COX-2 inhibitor celecoxib (brand name: Celebrex) is a potent tumor fighter, able to wipe out tumor cells that are resistant to conventional chemotherapies, according to an interdisciplinary team of researchers from the University of Southern California.

29 Aug 2005

First genetic evidence that protein synthesis is critical for the regulation of memory formation

A group of Montreal researchers has discovered that GCN2, a protein in cells that inhibits the conversion of new information into long-term memory, may be a master regulator of the switch from short-term to long-term memory.

29 Aug 2005

Anthrax test receives FDA approval

A method for identifying Bacillus anthracis, the causative agent of anthrax, has been cleared for diagnostic use by the U.S. Food and Drug Administration (FDA).

29 Aug 2005

Discovery of multiple isoforms of the p53 tumor suppressor protein

25 years after the initial discovery of p53, Dr. David Lane and colleagues at the University of Dundee have discovered multiple isoforms of the p53 tumor suppressor protein.

29 Aug 2005

New way to "image" the internal chemistry of bacteria

As part of the search for better ways to track and clean up soil contaminants, scientists at the U.S. Department of Energy's Brookhaven National Laboratory and Stony Brook University have developed a new way to "image" the internal chemistry of bacteria.

29 Aug 2005

New laboratory method for quickly detecting active anthrax proteins

A new laboratory method for quickly detecting active anthrax proteins within an infected blood sample at extremely low levels has been developed by researchers at the National Institute of Standards and Technology (NIST), the U.S. Army Medical Research Institute of Infectious Diseases and the National Cancer Institute.

29 Aug 2005

California wants cancer warnings on french fries and chips

In an attempt to stop restaurant chains such as McDonald's and Wendy's from selling french fries without some form of warning, Bill Lockyer the Attorney General for California has filed a lawsuit to force manufacturers of potato chips and french fries to warn consumers about a potential cancer-causing chemical found in the popular snacks.

29 Aug 2005

Leading medical journal says homeopathy no better than dummy drugs

Leading medical journal The Lancet has rubbished homeopathy and says it is no more value than dummy drugs.

29 Aug 2005

New way to count bugs in dirt

Don't call them the Dirt Doctors, or Sultans of Soil, they're just clever Lab guys. A team from Los Alamos National Laboratory has a paper in this week's Science Magazine with a new way to count bugs in dirt. Bacteria, that is, in the highly complex world beneath our feet.

29 Aug 2005

Study reveals functional link between emotion processing centers in the brain and certain physiological processes relevant to disease

The mere mention of a stressful word like "wheeze" can activate two brain regions in asthmatics during an attack, and this brain activity may be associated with more severe asthma symptoms, according to a study by University of Wisconsin-Madison researchers and collaborators.

29 Aug 2005