Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Researchers discover novel population of neutrophils that exhibit enhanced microbial killing activity

Case Western Reserve University researchers have discovered a novel population of neutrophils, which are the body's infection control workhorses. These cells have an enhanced microbial killing ability and are thereby better able to control infection.

25 Mar 2014

Protein known to promote cancer appears to give blood vessels strength and shape, researchers report

A protein known to promote cancer appears to give the blood vessels strength and shape, researchers report. When yes-associated protein, or YAP, is deleted from vascular smooth muscle cells during development, the protein makes thin-walled blood vessels that over-dilate in response to the usual pressure of blood flow, said Dr. Jiliang Zhou, vascular biologist at the Medical College of Georgia at Georgia Regents University.

25 Mar 2014

Researchers develop one-step analysis for detecting tumor markers in blood

Benign growth, or cancer? Tumor markers in the blood help determine whether the patient is afflicted with a malign tumor and whether it is excreting markers more vigorously - involving highly specific proteins. An increased concentration in the blood provides one indication of the disease for physicians. However, it has been quite expensive in time and effort to detect the markers thus far. This is because all kinds of molecules and proteins are teeming in the blood. To be able to detect a single specific one, doctors must first separate and purify the blood in several steps, and then isolate the marker they are searching for from the rest of the molecules.

25 Mar 2014

NeuroVive Pharmaceutical initiates research collaboration with A1M Pharma

NeuroVive Pharmaceutical AB (publ) and A1M Pharma AB (publ) have announced that the two companies are initiating a research collaboration in mitochondrial medicine. The partnership is governed by a collaboration agreement signed on 21 March 2014.

25 Mar 2014

Agios initiates AG-120 Phase 1 study to evaluate advanced solid tumors with IDH1 mutation

Agios Pharmaceuticals, Inc., a leader in the fields of cancer metabolism and inborn errors of metabolism, today announced dose administration for the first patient in a Phase 1 study of AG-120 in patients with advanced solid tumors with an isocitrate dehydrogenase-1 (IDH1) mutation.

25 Mar 2014

New technology gives tool to examine membrane proteins in natural environment of human cell

Scientists have a better way to study human proteins - large molecules that are part of every cell in the body - thanks to a new technology developed by University of Toronto researchers.

25 Mar 2014

Low dose injections of artificial properdin provide protection against septic diseases

Researchers at the University of Leicester have produced an artificial version of a naturally occurring protein, properdin, which has been found to successfully combat bacterial pneumonia and meningitis when tested in mice.

25 Mar 2014

New research reveals new complexity to nerve cells in brain that could affect future therapies

Research from the Oklahoma Medical Research Foundation reveals a new complexity to nerve cells in the brain that could affect future therapies aimed at altering mood and memory in humans.

25 Mar 2014

Study uncovers one way that p53 acts to prevent cancer cell invasion

The tumor suppressor p53 does all it can to prevent oncogenes from transforming normal cells into tumor cells by killing defective cells or causing them to become inactive.

25 Mar 2014

Study suggest that women are resistant to mutations that contribute to autism

It takes more mutations to trigger autism in women than in men, which may explain why men are four times more likely to have the disorder, according to a study published 26 February in the American Journal of Human Genetics1.

25 Mar 2014

CytRx initiates Phase 3 clinical trial to evaluate efficacy of aldoxorubicin in STS patients

CytRx Corporation (Nasdaq: CYTR), a biopharmaceutical research and development company specializing in oncology, today announced it has initiated a pivotal global Phase 3 clinical trial to evaluate the efficacy and safety of aldoxorubicin as a second-line treatment for patients with soft tissue sarcoma (STS) under a Special Protocol Assessment with the FDA.

25 Mar 2014

Nasal spray holds promise as potential alternative therapeutic approach for depression

A nasal spray that delivers a peptide to treat depression holds promise as a potential alternative therapeutic approach, research from the Centre for Addiction and Mental Health (CAMH) shows.

25 Mar 2014

High-protein meal and exercise recipe for calorie-burning in some women

New research shows that for some women, a high-protein meal followed by 30 minutes of moderate exercise is an effective way of burning calories, especially when compared to exercising on an empty stomach.

24 Mar 2014

CSP analogues may attenuate S. pneumoniae virulence, resistance

The spread of virulent, antibiotic-resistant strains of Streptococcus pneumoniae may be controllable through the use of competence-stimulating peptide analogues, US researchers believe.

24 Mar 2014

Rexahn provides updates on clinical development programs, reports full-year 2013 financial results

Rexahn Pharmaceuticals, Inc. a clinical stage biopharmaceutical company developing best-in-class therapeutics for the treatment of cancer, is providing an overview of its three clinical development programs and Year for the year ended December 31, 2013.

24 Mar 2014

New method can identify cancer's visible precursors with 97% certainty

Pancreatic cancer is often detected at a late stage, which results in poor prognosis and limited treatment options. Researchers at The University od Gothenburg, Sweden, have now developed a method which identifies the cancer's visible precursors with 97% certainty. The method, which is expected to aid in the early discovery of the cancer as well as minimize the risk of unnecessary surgery, may be introduced in patient care within five years.

24 Mar 2014

Cumulative amount of specific gene products affects changes in cell fate, say researchers

Johns Hopkins biologists have discovered that when biological signals hit cells in rhythmic waves, the magnitude of the cells' response can depend on the number of signaling cycles — not their strength or duration. Because such so-called “oscillating signaling cycles” are common in many biological systems, the scientists expect their findings in single-celled organisms to help explain the molecular workings of phenomena such as tissue and organ formation and fundamental forms of learning.

24 Mar 2014

DUF1220 protein domain also linked to severity of autism

The same gene family that may have helped the human brain become larger and more complex than in any other animal also is linked to the severity of autism, according to new research from the University of Colorado Anschutz Medical Campus.

24 Mar 2014

Drugs fail to "wake up" dormant reservoirs of HIV inside immune system T cells

Scientists at Johns Hopkins report that compounds they hoped would "wake up" dormant reservoirs of HIV inside immune system T cells - a strategy designed to reverse latency and make the cells vulnerable to destruction - have failed to do so in laboratory tests of such white blood cells taken directly from patients infected with HIV.

24 Mar 2014

Researchers find stress can delay pregnancy and double risk of infertility

Having difficulty getting pregnant can be an incredibly stressful experience for any couple. Now, for the first time, researchers have data that suggests preconception stress might play a role in infertility.

24 Mar 2014

Protein News and Research

Further Reading

Researchers discover novel population of neutrophils that exhibit enhanced microbial killing activity

Protein known to promote cancer appears to give blood vessels strength and shape, researchers report

Researchers develop one-step analysis for detecting tumor markers in blood

NeuroVive Pharmaceutical initiates research collaboration with A1M Pharma

Agios initiates AG-120 Phase 1 study to evaluate advanced solid tumors with IDH1 mutation

New technology gives tool to examine membrane proteins in natural environment of human cell

Low dose injections of artificial properdin provide protection against septic diseases

New research reveals new complexity to nerve cells in brain that could affect future therapies

Study uncovers one way that p53 acts to prevent cancer cell invasion

Study suggest that women are resistant to mutations that contribute to autism

CytRx initiates Phase 3 clinical trial to evaluate efficacy of aldoxorubicin in STS patients

Nasal spray holds promise as potential alternative therapeutic approach for depression

High-protein meal and exercise recipe for calorie-burning in some women

CSP analogues may attenuate S. pneumoniae virulence, resistance

Rexahn provides updates on clinical development programs, reports full-year 2013 financial results

New method can identify cancer's visible precursors with 97% certainty

Cumulative amount of specific gene products affects changes in cell fate, say researchers

DUF1220 protein domain also linked to severity of autism

Drugs fail to "wake up" dormant reservoirs of HIV inside immune system T cells

Researchers find stress can delay pregnancy and double risk of infertility

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