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Blood transfusion may increase risk of death in heart attack patients with anemia

When heart attack patients present in the emergency department with some degree of anemia, or anemic patients have a heart attack, physicians have a tendency, but not much guidance, about whether to provide a blood transfusion.

25 Dec 2012

Study demonstrates safety of using tPA for stroke in community hospital settings

From the moment a stroke occurs, patients must race against the clock to get treatment that can prevent lasting damage. Now, a new study shows the promise – and the challenges – of getting them state-of-the-art treatment safely at their local hospital, saving precious minutes.

21 Dec 2012

Roundup: Calif. hospitals fined over serious errors; Mass. pharmacy waiting period continues; Hospitals acquiring 'tough reimbursement climate' in Alabama?

Ten California hospitals received fines Thursday for errors that resulted in either serious injury or death to a patient. The California Department of Public Health issued a total of $785,000 in penalties for errors that include removing the wrong kidney, leaving surgical objects behind and failing to call for assistance when a patient began bleeding excessively (Gorman, 12/21).

21 Dec 2012

New MRI scans accurately measure damage to blood-brain barrier in stroke victims

Johns Hopkins researchers have developed a new way of looking at standard MRI scans that more accurately measures damage to the blood-brain barrier in stroke victims, a process they hope will lead to safer, more individualized treatment of blood clots in the brain and better outcomes.

21 Dec 2012

Updated U.S. prescribing information for Boehringer Ingelheim’s Pradaxa

Boehringer Ingelheim Pharmaceuticals, Inc. today announced that the U.S. prescribing information for Pradaxa (dabigatran etexilate mesylate) capsules was updated to include a contraindication related to use in patients with mechanical prosthetic heart valve replacement.

21 Dec 2012

FDA allows marketing of Angiotech's Bio-Seal Lung Biopsy Tract Plug System

The U.S. Food and Drug Administration today allowed marketing of the Bio-Seal Lung Biopsy Tract Plug System, a device that seals punctures left by biopsies performed to confirm a diagnosis of suspected lung conditions.

20 Dec 2012

Clopidogrel pretreatment for PCI does not reduce risk of overall mortality

Among patients scheduled for a percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries), pretreatment with the antiplatelet agent clopidogrel was not associated with a lower risk of overall mortality but was associated with a significantly lower risk of major coronary events, according to a review and meta-analysis of previous studies published in the December 19 issue of JAMA.

19 Dec 2012

Hospital MRIs may effectively predict long-term outcomes for people with mild TBI

Hospital MRIs may be better at predicting long-term outcomes for people with mild traumatic brain injuries than CT scans, the standard technique for evaluating such injuries in the emergency room, according to a clinical trial led by researchers at the University of California, San Francisco (UCSF) and the San Francisco General Hospital and Trauma Center (SFGH).

19 Dec 2012

Misoprostol helps prevent postpartum haemorrhage after home births

Research brings together evidence about the potential for misoprostol to prevent bleeding after home births in low resource countries.

18 Dec 2012

LSDF announces five new grants to support commercial development of health-care products

The Life Sciences Discovery Fund (LSDF) today announced over $1 million in five awards to support commercial development of new health and health-care products within both the non-profit and for-profit sectors in Washington.

18 Dec 2012

Pelvic exams frequently performed for reasons that are medically unjustified

The pelvic exam, a standard part of a woman's gynecologic checkup, frequently is performed for reasons that are medically unjustified, according to the authors of a UCSF study that may lay the groundwork for future changes to medical practice.

17 Dec 2012

Concern over enoxaparin bleeding risk in patients with moderate renal impairment

The low molecular weight heparin enoxaparin is associated with an increased risk for major bleeding in patients who have moderate renal impairment, say US scientists in findings that have prompted calls for updates to dosing recommendations.

14 Dec 2012

Interim results from Inspiration’s OBI-1 and IB1001 hemophilia clinical study

Inspiration Biopharmaceuticals, Inc. (Inspiration) announced interim clinical results for the company's two lead product candidates, an intravenous recombinant porcine FVIII (OBI-1) in the treatment of serious bleeds in acquired hemophilia A (AHA) and an intravenous recombinant FIX (IB1001) for the treatment and prevention of bleeding in children less than 12 years of age with hemophilia B.

13 Dec 2012

Researchers decipher mechanism by which anophelin binds to thrombin

An international project lead by the Molecular and Cell Biology Institute of Porto University with the participation of researchers from IMIM (Hospital del Mar Medical Research Institute) has, for the first time ever, deciphered the mechanism by which a substance called anophelin binds to an enzyme (thrombin) involved in the process of blood coagulation.

12 Dec 2012

Bleeding News and Research

Blood transfusion may increase risk of death in heart attack patients with anemia

Study demonstrates safety of using tPA for stroke in community hospital settings

Roundup: Calif. hospitals fined over serious errors; Mass. pharmacy waiting period continues; Hospitals acquiring 'tough reimbursement climate' in Alabama?

New MRI scans accurately measure damage to blood-brain barrier in stroke victims

Updated U.S. prescribing information for Boehringer Ingelheim’s Pradaxa

FDA allows marketing of Angiotech's Bio-Seal Lung Biopsy Tract Plug System

Clopidogrel pretreatment for PCI does not reduce risk of overall mortality

Hospital MRIs may effectively predict long-term outcomes for people with mild TBI

Misoprostol helps prevent postpartum haemorrhage after home births

LSDF announces five new grants to support commercial development of health-care products

Pelvic exams frequently performed for reasons that are medically unjustified

Concern over enoxaparin bleeding risk in patients with moderate renal impairment

Interim results from Inspiration’s OBI-1 and IB1001 hemophilia clinical study

Researchers decipher mechanism by which anophelin binds to thrombin

Studies examine current treatment standards for patients with clotting disorders

Cedars-Sinai first in Los Angeles County to achieve Comprehensive Stroke Center Certification

AMAG presents new data from two ferumoxytol phase III trials on IDA at ASH annual meeting

Thulium vapoenucleation well-tolerated for treating benign prostate obstruction

Natural product to combat menopause symptoms

Communication and checklists may lead to fewer surgical complications

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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