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Tau reduction impacts brain cells involved in creating abnormal activity

With the school year well on its way, we all recognize the importance of getting students energized. However, we also know that overstimulated children can wreak havoc on a classroom, leaving a teacher trying to regain control of their group. The situation is very similar in the brain, where cells must remain active - but in an orderly manner - to carry out their many important tasks.

20 Oct 2021

Brain's motor cortex may play a larger role in Parkinson’s disease, study reveals

The role of neuron and dopamine loss in Parkinson's Disease (PD) has long been recognized by neuroscientists.

19 Oct 2021

Researchers identify brain circuitry involved in emotional aspects of chronic pain

Negative emotional states and physical pain are intimately connected. Numerous people who suffer from chronic, persistent pain also deal with negative emotions and loss of motivation.

18 Oct 2021

FDA-approved drug encourages sensory neurons to regrow after injury

A spinal cord injury damages the lines of communication between the body and brain, impeding the signals that drive movement and sensation.

18 Oct 2021

Study uncovers neuronal circuitry that may play a key role in mediating pain-induced anhedonia

A new study published today in Nature Neuroscience has uncovered neuronal circuitry in the brain of rodents that may play an important role in mediating pain-induced anhedonia - a decrease in motivation to perform reward-driven behaviors.

18 Oct 2021

Neuroscientists discover specific brain circuit that triggers cocaine relapse in mice

Relapse is a common feature of addiction recovery – two in three patients treated for substance use disorder in the United States relapse within 12 months, according to the Journal of the American Medical Association.

18 Oct 2021

Researchers identify protein that plays a key role in how the brain regulates appetite and metabolism

Researchers from the Okinawa Institute of Science and Technology Graduate University have identified a protein that plays a key role in how the brain regulates appetite and metabolism.

18 Oct 2021

Researchers explore how opioids may have become so widely abused

Researchers may have uncovered new answers on how to create safer opioids. Design a new opioid to bypass the part of brain that feels pleasure, but retain the analgesic properties, which make opioids one of the most effective pain relievers.

15 Oct 2021

Salk researchers discover how the brain ignores distracting signals to coordinate movements

As you read this article, touch receptors in your skin are sensing your environment. Your clothes and jewelry, the chair you're sitting on, the computer keyboard or mobile device you're using, even your fingers as they brush one another unintentionally - each touch activates collections of nerve cells.

15 Oct 2021

Researchers identify neurons and signaling pathways that make sexually receptive females more active

Scientists have known for a century that female animals become more active just as they are about to ovulate, a behavior that evolved to enhance their chances of mating when they are fertile.

15 Oct 2021

Study reveals a detrimental role of the immune system in Lewy body dementias

T-cells respond to buildups of alpha-synuclein, the aggregated protein clumps that are a feature of neurodegenerative diseases including dementia with Lewy bodies and Parkinson's disease (PD), according to a Northwestern Medicine study published in Science.

14 Oct 2021

New method to diagnose anosmia

In a recent study, researchers discuss a new method of tracking the Nav1.7 channel to reduce the reliance on more invasive diagnostic measures.

13 Oct 2021

A mucoadhesive polymer with anti-SARS-COV-2 activity in vitro and in vivo

The team has evaluated a low molecular weight chitosan derivative as a candidate preventing the viral entry into mammalian nasal epithelial cells to limit the spread of COVID-19.

12 Oct 2021

Study uncovers mechanism that may underlie greater sensitivity of certain skin regions

Some parts of the body - our hands and lips, for example - are more sensitive than others, making them essential tools in our ability to discern the most intricate details of the world around us.

11 Oct 2021

Common oral diuretic pill may be a potential candidate for Alzheimer's treatment

A commonly available oral diuretic pill approved by the U.S. Food and Drug Administration may be a potential candidate for an Alzheimer's disease treatment for those who are at genetic risk, according to findings published in Nature Aging.

11 Oct 2021

Researchers discover molecules in the blood that can indicate impending dementia

Researchers at the DZNE and the University Medical Center Göttingen (UMG) have identified molecules in the blood that can indicate impending dementia. Their findings, which are presented in the scientific journal "EMBO Molecular Medicine", are based on human studies and laboratory experiments. Various university hospitals across Germany were also involved in the investigations.

11 Oct 2021

The neurological effects of COVID-19

What is the relationship between COVID-19 and the brain? A new review published in Tropical Biomedicine summarizes the key findings on how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes severe COVID-19 infection, disrupts brain activity and produces a range of long-term neurological disorders.

10 Oct 2021

New technique elucidates fiber architecture of the brain's white matter

The human brain is a constant buzz of activity, with its 86 billion nerve cells (neurons) sending electrical signals from one region of the brain to another. The signals travel along the white matter fibers, a maze of wire-like fibers, ultimately giving rise to all brain functions.

7 Oct 2021

Planar cell polarity pathway found to be responsible for the formation and maintenance of synapses

Within the brain and other parts of the nervous system, synapses are key junctional points in between neurons (the nerve cells) where critical signals are transmitted. More specifically, the "glutamatergic" synapses are the prime "excitatory" synapse junctions that neurons use to activate each other and are known to have broad diversity in size and shape.

7 Oct 2021

Mouse brain atlas may help understand the complex circuits of the human brain

The circuits of the human brain contain more than 100 billion neurons, each linked to many other neurons via thousands of synaptic connections, resulting in a three-pound organ that is profoundly more complex than the sum of its innumerable parts.

7 Oct 2021

Neurons News and Research

Tau reduction impacts brain cells involved in creating abnormal activity

Brain's motor cortex may play a larger role in Parkinson’s disease, study reveals

Researchers identify brain circuitry involved in emotional aspects of chronic pain

FDA-approved drug encourages sensory neurons to regrow after injury

Study uncovers neuronal circuitry that may play a key role in mediating pain-induced anhedonia

Neuroscientists discover specific brain circuit that triggers cocaine relapse in mice

Researchers identify protein that plays a key role in how the brain regulates appetite and metabolism

Researchers explore how opioids may have become so widely abused

Salk researchers discover how the brain ignores distracting signals to coordinate movements

Researchers identify neurons and signaling pathways that make sexually receptive females more active

Study reveals a detrimental role of the immune system in Lewy body dementias

New method to diagnose anosmia

A mucoadhesive polymer with anti-SARS-COV-2 activity in vitro and in vivo

Study uncovers mechanism that may underlie greater sensitivity of certain skin regions

Common oral diuretic pill may be a potential candidate for Alzheimer's treatment

Researchers discover molecules in the blood that can indicate impending dementia

The neurological effects of COVID-19

New technique elucidates fiber architecture of the brain's white matter

Planar cell polarity pathway found to be responsible for the formation and maintenance of synapses

Mouse brain atlas may help understand the complex circuits of the human brain

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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