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Neuroprotection powers for phenytoin in acute optic neuritis

Selective sodium channel blockade with the anti-epileptic drug phenytoin protects against acute demyelinating optic neuritis, researchers report.

29 Jan 2016

Neurons protect intestinal tissue from over-inflammation

The immune system exercises constant vigilance to protect the body from external threats--including what we eat and drink. A careful balancing act plays out as digested food travels through the intestine. Immune cells must remain alert to protect against harmful pathogens like Salmonella, but their activity also needs to be tempered since an overreaction can lead to too much inflammation and permanent tissue damage.

25 Jan 2016

UAB study shows IL-37 protein suppresses inflammatory response after spinal cord injury

Spinal cord injuries cause severe functional disabilities in those who sustain them, including paraplegia or tetraplegia, depending on the scale of the injury. This is due to the degeneration of the spinal pathways that carry nerve signals from the brain to the different parts of the body and vice versa, resulting in loss of mobility and sensitivity underneath the injured area.

22 Jan 2016

Allergan announces publication of VIBERZI Phase III trial results in The New England Journal of Medicine

Allergan plc announced today the publication of the positive results of the Phase III trials of VIBERZITM C IV (eluxadoline) for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in the January 21 issue of The New England Journal of Medicine.

21 Jan 2016

Scientists solve atomic structure of ubiquitin ligase complex that plays key role in protein degradation

Scientists at Sanford Burnham Prebys Medical Discovery Institute have solved the atomic structure of a unique ubiquitin ligase complex. Ubiquitin is best known for its role in protein degradation, but more recently seen as important for cell signaling, DNA repair, anti-inflammatory, and immune responses.

21 Jan 2016

Study outlines new model to help predict age-related response to hepatitis B vaccine

Physicians have known for years that patients respond differently to vaccines as they age. There may soon be a new way to predict and enhance the effectiveness of vaccinations, in particular the hepatitis B vaccine.

20 Jan 2016

GBI Research says COPD therapeutics pipeline lacks innovation

Analysis from business intelligence provider GBI Research - Frontier Pharma: Chronic Obstructive Pulmonary Disease (COPD) - Identifying and Commercializing First-in-Class Innovation - states that while currently-available drugs aim to manage the frequency and severity of symptoms associated with COPD, none have been shown to modify long-term disease progression.

19 Jan 2016

Researchers confirm that cranberry extract helps fight UTIs in breastfed children under age one

Researchers from the universities of Granada (Spain) and Kvopio (Finland) have confirmed that cranberry extract helps fighting urinary tract infections (UTIs) in breastfed babies under one year of age.

18 Jan 2016

Using statins before and after heart surgery can help reduce cardiac complications, mortality risks

Using statins before and after coronary artery bypass grafting (CABG) surgery can help reduce cardiac complications, such as atrial fibrillation, following surgery and also can reduce the risk of death during and after surgery, according to a review article posted online today by The Annals of Thoracic Surgery.

13 Jan 2016

Inflammation associated with elevated glutamate in the brain could guide depression treatments

Psychiatrists investigating depression have been energized in recent years by reports of rapid, successful treatment with drugs that interfere with the brain chemical glutamate, such as the anesthetic ketamine.

13 Jan 2016

Pre-existing nutritional deficits, immune dysfunction may increase hepatitis E risk during pregnancy

Researchers from the Johns Hopkins Bloomberg School of Public Health have found a link between pre-existing nutritional deficits and immune dysfunction and the risk of hepatitis E infection during pregnancy.

12 Jan 2016

Common painkiller diclofenac has significant anti-cancer properties

Diclofenac, a common painkiller, has significant anti-cancer properties, according to researchers from the Repurposing Drugs in Oncology project.

12 Jan 2016

Novel anti-inflammatory agents could control hyper-inflammatory responses to fungal infection

The most frequent fungal threat to humans, Candida albicans, is a common cause oral and genital infection. The fungal infections are often worsened by overwhelming inflammatory responses in the body and cause high mortality among risk groups. Umeå University doctoral student Ava Hosseinzadeh has discovered two novel anti-inflammatory agents, an antioxidant and an anti-inflammatory molecule, which could be used to control the hyper-inflammatory responses to the fungal infection.

12 Jan 2016

Low-oxygen exposure shortly after birth may increase learning and behavioral disorder risks

New research published in the Journal of Leukocyte Biology, shows that the development of white matter in the mouse brains is delayed when they are exposed to chronic low oxygen levels shortly after birth.

7 Jan 2016

FDA permits Sound Pharmaceuticals to start SPI-1005 clinical trial for treatment of Meniere's Disease

Sound Pharmaceuticals is pleased to announce that it began enrolling a clinical trial to test SPI-1005 in the treatment of Meniere's Disease (MD). MD or idiopathic endolymphatic hydrops is an inner ear disease that involves episodic vertigo, sensorineural hearing loss, and tinnitus.

5 Jan 2016

Drug-microbe interactions may contribute to adverse effects, lessen effectiveness of NSAID

A nonsteroidal anti-inflammatory drug (NSAID) changed the composition and diversity of gut microbes, which in turn shaped how the drug is broken down and ultimately, cut its effectiveness, according to an animal study from the Perelman School of Medicine at the University of Pennsylvania.

5 Jan 2016

Back pain becoming more common in children and adolescents

According to a new literature review in the January issue of the Journal of the American Academy of Orthopaedic Surgeons, it's becoming more common for children and adolescents to seek medical care for back pain. Even with expensive, advanced tests like MRI scans, doctors may not be able to find the exact cause for the pain.

5 Jan 2016

Araim Pharmaceuticals forms new strategic collaboration with Vault Bioventures to market novel peptides

Araim Pharmaceuticals has formed a long-term strategic partnership with Vault Bioventures to facilitate the advancement to market of its novel peptide library which targets devastating injuries and chronic diseases underserved by current therapies.

4 Jan 2016

MUSC researchers receive $1.68 million NIH grant to study better treatment for chronic pancreatitis, diabetes

MUSC researchers received a $1.68 million National Institutes of Health grant to explore a better treatment for chronic pancreatitis, with the hopes that it also may shed light on a future cure for patients with type 1 diabetes.

4 Jan 2016

Natural dietary supplement Arthrem significantly reduces pain and stiffness in osteoarthritis patients

New Zealand company Promisia Integrative Limited, announced today significant positive results from a clinical trial on their natural dietary supplement Arthrem. The results have been published in the December 2015 issue of Clinical Rheumatology, a prestigious international peer reviewed medical journal.

31 Dec 2015

Anti Inflammatory News and Research

Neuroprotection powers for phenytoin in acute optic neuritis

Neurons protect intestinal tissue from over-inflammation

UAB study shows IL-37 protein suppresses inflammatory response after spinal cord injury

Allergan announces publication of VIBERZI Phase III trial results in The New England Journal of Medicine

Scientists solve atomic structure of ubiquitin ligase complex that plays key role in protein degradation

Study outlines new model to help predict age-related response to hepatitis B vaccine

GBI Research says COPD therapeutics pipeline lacks innovation

Researchers confirm that cranberry extract helps fight UTIs in breastfed children under age one

Using statins before and after heart surgery can help reduce cardiac complications, mortality risks

Inflammation associated with elevated glutamate in the brain could guide depression treatments

Pre-existing nutritional deficits, immune dysfunction may increase hepatitis E risk during pregnancy

Common painkiller diclofenac has significant anti-cancer properties

Novel anti-inflammatory agents could control hyper-inflammatory responses to fungal infection

Low-oxygen exposure shortly after birth may increase learning and behavioral disorder risks

FDA permits Sound Pharmaceuticals to start SPI-1005 clinical trial for treatment of Meniere's Disease

Drug-microbe interactions may contribute to adverse effects, lessen effectiveness of NSAID

Back pain becoming more common in children and adolescents

Araim Pharmaceuticals forms new strategic collaboration with Vault Bioventures to market novel peptides

MUSC researchers receive $1.68 million NIH grant to study better treatment for chronic pancreatitis, diabetes

Natural dietary supplement Arthrem significantly reduces pain and stiffness in osteoarthritis patients

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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