Cytokine News and Research

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What change does prokineticin 2/Bv8 have in human hepatocellular carcinoma?

Liver hepatocarcinoma is a highly vascularized cancer, and more and more research is focused on the molecules controlling angiogenesis.

19 Mar 2008

Do bacterial combinations result in enhanced cytokine production? No!

Probiotic bacteria, defined as living microorganisms that have beneficial effects on human health, have been used for the prevention and treatment of a diverse range of disorders.

19 Mar 2008

Cell therapy for rejuvenating aged brain by injection of human umbilical cord blood

When human umbilical cord blood cells (UCBC) were injected into aged laboratory animals, researchers at the University of South Florida (USF) found improvements in the microenvironment of the hippocampus region of the animals' brains and a subsequent rejuvenation of neural stem/progenitor cells.

11 Mar 2008

New discovery on programmed cell death

Investigators at St. Jude Children's Research Hospital have discovered a dance of proteins that protects certain cells from undergoing apoptosis, also known as programmed cell death. Understanding the fine points of apoptosis is important to researchers seeking ways to control this process.

1 Mar 2008

Effect of tumor necrosis factor a inhibitors on heart failure risk in rheumatoid arthritis

A chronic autoimmune disease, rheumatoid arthritis (RA) is characterized by persistent inflammation of the synovial membrane and progressive joint destruction.

28 Feb 2008

Atypical protein kinase C stabilizes SRC-3 levels in breast cancer cells

A new study provides valuable insight into a previously undescribed mechanism that regulates a prominent cancer-associated protein.

28 Feb 2008

Minocycline antibiotic may prevent Japanese encephalitis

Two researchers from National Brain Research Center (NBRC) suggest that a common antibiotic called minocycline may prevent children from death due to Japanese encephalitis (JE), or commonly known as brain fever.

20 Feb 2008

New blood test six times more effective for tuberculosis control

In a landmark study electronically published today in the American Journal of Respiratory and Critical Care Medicine, a blood test for detecting TB infection, QuantiFERON(R)-TB Gold (QFT), has been shown to be six times more accurate than the conventional tuberculin skin test (TST) at predicting which tuberculosis (TB)-exposed individuals will go on to develop TB disease.

18 Feb 2008

Researchers seek trial participants for experimental HIV vaccine called PENNVAX-B

University of Pennsylvania School of Medicine researchers are recruiting healthy, HIV-negative adults to participate in a phase I clinical trial of an experimental HIV vaccine called PENNVAX-B, a DNA-based vaccine which is made using synthetic DNA-based HIV genes.

4 Feb 2008

Etanercept drug reverses early symptoms of Alzheimer's in 10 minutes

Scientists in the U.S. say a drug which can reverse some of the early symptoms of Alzheimer's disease takes effect within 10 minutes.

14 Jan 2008

New study highlights importance soluble proteins, called cytokines, in Alzheimer's

An extraordinary new scientific study, which for the first time documents marked improvement in Alzheimer's disease within minutes of administration of a therapeutic molecule, has just been published in the Journal of Neuroinflammation .

10 Jan 2008

Stress causes whole body deterioration

Stress, to put it bluntly, is bad for you. It can kill you, in fact. A study now reveals that stress causes deterioration in everything from your gums to your heart and can make you more susceptible to everything from the common cold to cancer.

9 Jan 2008

New insight into factors that drive muscle-building stem cells

A report in the January issue of Cell Metabolism, a publication of Cell Press, provides new evidence explaining how stem cells known as satellite cells contribute to building muscles up in response to exercise.

9 Jan 2008

Two genes are important key to regulating immune response

A research team at Weill Cornell Medical College in New York City has identified two genes that may be crucial to the production of an immune system cytokine called interleukin-10 (IL-10)

2 Jan 2008

Molecular 'trip switch' shuts down inflammatory response

Like a circuit breaker that prevents electrical wiring from overheating and bringing down the house, a tiny family of three molecules stops the immune system from mounting an out-of-control, destructive inflammatory response against invading pathogens, researchers at the Salk Institute for Biological Studies have found.

14 Dec 2007

Zebrafish study shows key enzyme in gut is a peacemaker

University of Oregon scientists, using zebrafish to study the gastrointestinal tract, say that an enzyme long assumed to be involved in digestion instead is a detoxifying traffic cop, maintaining a friendly rapport between resident gut bacteria and cells.

13 Dec 2007

Researchers uncover delicate protein balance behind the immune system response

A team of researchers from the University of Pennsylvania School of Veterinary Medicine has identified the protein interactions involved in the immune system process that fights infection yet, in certain inflammatory diseases, runs amok and attacks friendly tissue.

10 Dec 2007

Discovery of key acute myeloid leukemia gene

A gene called N-Myc leads a double life in certain white blood cells, helping to trigger a cancer called acute myeloid leukemia (AML) under some conditions while triggering apoptosis, or cell suicide, under other conditions, according to results of a mouse study done by investigators at St. Jude Children's Research Hospital.

27 Nov 2007

Discovery of new signaling molecule could lead to the development of new treatments for cancer

Investigators at St. Jude Children's Research Hospital have discovered a new signaling molecule that prevents immune responses from running amok and damaging the body.

21 Nov 2007

Monkeys fend off AIDS-like symptoms with enhanced HIV vaccine

Researchers at the University of Pennsylvania School of Medicine have discovered that using an immune system gene to enhance a vaccine used to study HIV in macaque monkeys provides the animals with greater protection against simian HIV (SHIV) than an unmodified vaccine.

21 Nov 2007