Laboratory News and Research

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Stem cell therapy used to fight amyotrophic lateral sclerosis

A team of Utahns is collaborating on a stem cell therapy to fight amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

21 Apr 2009

Pancreatic cancer cells targeted with combo therapy

A combination of two targeted therapies packs a powerful punch to kill pancreatic cancer cells in the laboratory, Mayo Clinic cancer researchers report.

21 Apr 2009

Pregnancy hormone hCG protects against breast cancer even in short-term treatments

One of the most effective ways to prevent breast cancer is through a full-term pregnancy at an early age.

21 Apr 2009

New insights into protein p75's role Alzheimer's disease

New research at the Salk Institute for Biological Studies casts the role of a neuronal growth factor receptor - long suspected to facilitate the toxic effects of beta amyloid in Alzheimer's disease - in a new light, suggesting the molecule actually protects the neuron in the periphery from beta amyloid-induced damage.

21 Apr 2009

Potential new drug blocks pathway of deadliest cancer

Scientists at Cancer Research Technology Ltd (CRT) will present exciting new findings showing that a potent and selective inhibitor of protein kinase D called CRT0066101, inhibits the growth of pancreatic tumours.

20 Apr 2009

Is metabolic character different between men and women with gallstone disease?

There are a cluster of metabolic syndrome, that include obesity, high level of fasting plasma glucose, hypertriglyceridemia and hypertension, which is closely associated with the increased morbidity and mortality caused by several of the most common diseases including diabetes, hypertension, cardiovascular diseases, cancer and gallstone disease.

20 Apr 2009

New insights into transcription factors in human cells

Bioinformatics researchers from UC San Diego just moved closer to unlocking the mystery of how human cells switch from "proliferation mode" to "specialization mode."

20 Apr 2009

Healthcare reform should start with paying evidence-based financial incentives to doctors

Healthcare Reform should start with "evidence-based reimbursement", structuring physician payment incentives around existing empirical evidence of clinical benefit, which would improve quality and reduce the cost of healthcare, says a commentary written by two cardiologists and published in Circulation: Cardiovascular Quality and Outcomes .

20 Apr 2009

Fulvestrant influences the effects of chemotherapy drugs on breast cancer cells

Researchers from The Cancer Institute of New Jersey (CINJ) are converging on Denver for the 100th Annual Meeting of the American Association for Cancer Research (AACR) to share their findings on a combined treatment targeting breast cancer that is stimulated by the hormone estrogen (estrogen receptive positive).

20 Apr 2009

First noninvasive technique to accurately predict mutations in human brain tumors

Donald O'Rourke, MD, Associate Professor of Neurosurgery at the University of Pennsylvania School of Medicine and colleagues, were able to accurately predict the specific genetic mutation that caused brain cancer in a group of patients studied using magnetic resonance imaging (MRI).

20 Apr 2009

Discovery of key processes in the brain that control perception of emotional events

Research performed by Nicole Lauzon and Dr. Steven Laviolette of the Schulich School of Medicine & Dentistry at The University of Western Ontario has found key processes in the brain that control the emotional significance of our experiences and how we form memories of them.

20 Apr 2009

Statins may be useful in patients with tamoxifen-resistant breast cancer

Breast cancer cells in the laboratory that don't respond to tamoxifen may be producing high amounts of cholesterol in order to provide a kind of shield against the drug, say researchers at Georgetown University Medical Center (GUMC).

20 Apr 2009

Urine may show if a smoker is at risk for lung cancer

Researchers may have uncovered why lung cancer afflicts some smokers and not others, according to data presented at the American Association for Cancer Research 100th Annual Meeting 2009.

20 Apr 2009

Inhaled smoke shifts male cardiovascular system into overdrive

Secondhand tobacco smoke and smoke from cooking oil and wood smoke affected cardiovascular function of men and women who were exposed to small doses of the smoke for as little as 10 minutes, according to a study from the University of Kentucky.

20 Apr 2009

Marine derived compound may lead to new leukemia treatments

Kapakahines, marine-derived natural products isolated from a South Pacific sponge in trace quantities, have shown anti-leukemia potential, but studies have been all but stalled by kapakahines' lack of availability.

20 Apr 2009

Rockefeller University Hospital opens new Sleep Research Center

A good night's sleep is good for your health, but the details have long been sketchy.

20 Apr 2009

Study looks at exposure to vibration in workplace

Speaking on April 19 at the Experimental Biology 2009 meeting in New Orleans, Dr. Kristine Krajnak, a team leader in the Engineering and Control Technologies Branch of the Health Effects Laboratory Division of NIOSH in Morgantown, West Virginia, describes results from the first study to directly link the different physical responses of tissue that occur with exposure to different vibration frequencies with biological mechanisms underlying the development of vascular dysfunction.

20 Apr 2009

Oral contraceptives impair muscle mass gains in young women

Many active young women use oral contraceptives (OC) yet its effect on their body composition and exercise performance has not been thoroughly studied.

20 Apr 2009

Newly discovered epidermal growth factor receptor active in human pancreatic cancers

Finally some promising news about pancreatic cancer, one of the most fatal cancers, due to the difficulties of early detection and the lack of effective therapies: Johns Hopkins University pathologist Akhilesh Pandey has identified an epidermal growth factor receptor aberrantly active in approximately a third of the 250 human pancreatic cancers studied.

20 Apr 2009

New therapy for pancreatic cancer achieves tumor remission and prevents recurrence

Pancreatic cancer remains one of the deadliest cancers, but researchers may have found a combination therapy to reduce cancer stem cells and stop pancreatic cancer growth. Results will be presented at the American Association for Cancer Research 100th Annual Meeting 2009.

20 Apr 2009