Laboratory News and Research

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Handheld device provides on-the-spot DNA analysis to test tolerance to prescription drugs

A handheld device to predict whether patients will respond adversely to medication is one step closer to the market, thanks to a new partnership.

18 Feb 2009

Asthma drugs need to be maintained for continued benefit

Children whose asthma improved while taking steroid drugs for several years did not see those improvements continue after stopping the drugs, new results from a comprehensive childhood asthma study show.

18 Feb 2009

A stem cell bandage for your knee

Building on his previous work, Hollander and his team, which included Dr Wael Kafienah and Dr John Tarlton, announced in 2005 they had, for the first time ever, successfully grown human cartilage from a patient's own bone marrow stem cells.

18 Feb 2009

Braconid parasite wasps have practiced gene therapy for a hundred million years

Braconid parasite wasps and their caterpillar hosts form a unique host-parasite model: the wasps lay their eggs inside the caterpillars and simultaneously inject some viral particles to get around the host's defenses and control its physiology.

17 Feb 2009

New software speeds enzyme design

A Duke University-led team has brought powerful software to the never-ending arms race between antibiotics and germs.

16 Feb 2009

Dendritic cells as a new player in arteries and heart valves

In 1973, Ralph M. Steinman launched a new scientific discipline when he published his discovery of the dendritic cell, an odd-shaped player in the immune system.

16 Feb 2009

Boosting its infectivity turns benign virus into good gene therapy carrier for cystic fibrosis

Researchers from the University of California, Berkeley, and the University of Iowa have turned a relatively benign virus into a highly infectious form that is ideal as a carrier for gene therapy.

16 Feb 2009

Radioimmunotherapy shows promise for HIV infection and viral cancers

Scientists at Albert Einstein College of Medicine of Yeshiva University have piggybacked antibodies onto radioactive payloads to deliver doses of radiation that selectively target and destroy microbial and HIV-infected cells.

16 Feb 2009

New understanding of health implications of nanoparticles

The smallest nano-sized silica particles used in biomedicine and engineering likely won't cause unexpected biological responses due to their size, according to work presented today.

16 Feb 2009

Mouse model mimics hyperglycemia, aids in diabetes research

UT Southwestern Medical Center researchers have genetically engineered a laboratory mouse in which pancreatic beta cells can regenerate after being induced to die.

16 Feb 2009

Molecules self-assemble to provide new therapeutic treatments

Researchers in the laboratory of Samuel I. Stupp at Northwestern University have an interesting approach for tackling some major health problems: gather raw materials and then let them self-assemble into structures that can address a multitude of medical needs.

16 Feb 2009

New device decreases wait times for patients needing immunotherapy

Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have created a device that significantly decreases the time needed to produce genetically manipulated T cells in preclinical tests for leukemia.

16 Feb 2009

Air pollution dangerously high around some U.S. schools

Air pollution is dangerously high around schools near some U.S. industrial plants, according to a recent study involving researchers from the University of Maryland and Johns Hopkins University.

16 Feb 2009

New approaches to prevent transplant rejection

To prevent the rejection of newly transplanted organs and cells, patients must take medicines that weaken their entire immune systems.

15 Feb 2009

Discovery of new prostate cancer marker

Howard Hughes Medical Institute researchers have identified a new biological marker present in the urine of patients with prostate cancer that indicates whether the cancer is progressing and spreading.

15 Feb 2009

Statistical analysis could yield new drug target for multiple sclerosis

An elaborate statistical analysis of genes from more than 7,000 individuals has identified an amino acid that appears to be a major risk factor for multiple sclerosis, a devastating autoimmune disorder that afflicts 2.5 million people worldwide.

15 Feb 2009

Novel blood test for hepatitis C

A novel blood test could bring a breakthrough in the battle against the dangerous hepatitis-C virus.

15 Feb 2009

New insight into why gambling is so attractive to some

A new study demonstrates that when gambling, almost winning promotes significant recruitment of win-related circuitry within the brain and enhances the motivation to gamble.

15 Feb 2009

Molecular machine turns packaged messenger RNA into a linear transcript

For RNA, the gateway to a productive life outside the nucleus is the nuclear pore complex, an amalgamation of 30 kinds of proteins that regulates all traffic passing through the nuclear membrane.

11 Feb 2009

Healthy people with high urinary protein levels have elevated kidney disease risk

Measuring the amount of protein lost in the urine can identify individuals at risk of developing kidney disease, according to a study appearing in the April 2009 issue of the Journal of the American Society Nephrology (JASN).

11 Feb 2009