Genetic Engineering News and Research

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Transposagen, CDI enter license agreement for iPS cell line production

Transposagen Biopharmaceuticals, a leader in genetic modification technology, announced today that it has entered into a non-exclusive license agreement with Cellular Dynamics International, the world's largest producer of human induced pluripotent stem cell lines and tissue cells for drug discovery and safety.

6 Jan 2011

Administration of therapeutic hypothermia for TBI should depend on clinical condition of individual patients

Lowering the body temperature of patients soon after they have suffered a severe brain injury may reduce neurologic complications and improve outcomes. The safety of therapeutic hypothermia for traumatic brain injury (TBI) has been demonstrated in national studies. According to a Roundtable Discussion of renowned experts in the field, when and how it is administered should depend on the clinical condition of individual patients.

5 Jan 2011

Safe vaccine protects mice against effects of cocaine

Researchers have produced a lasting anti-cocaine immunity in mice by giving them a safe vaccine that combines bits of the common cold virus with a particle that mimics cocaine.

5 Jan 2011

New mouse model with deficiency of lipoprotein lipase in neurons

Researchers at the University of Colorado School of Medicine have created a new and exciting mouse model to study how lipid sensing and metabolism in the brain relate to the regulation of energy balance and body weight. The research team, led by Hong Wang, PhD, created mice with a deficiency of lipoprotein lipase (LPL) in neurons, and observed two important reactions.

5 Jan 2011

Removal of ZIP proteins from hippocampus cell protects them from injury

Researchers in the Blue Bird Circle Developmental Neurogenetics Laboratory in the department of neurology at Baylor College of Medicine have discovered that zinc enters cells through specialized protein gates known as ZIP transporters, and removing these ZIP proteins from cells in the hippocampus significantly protects them from injury.

5 Jan 2011

Vaccine blocks cocaine high in mice - human trials likely

Researchers have produced a lasting anti-cocaine immunity in mice by giving them a safe vaccine that combines bits of the common cold virus with a particle that mimics cocaine.

4 Jan 2011

NEI awards Case Western Reserve $10M for study of retinal diseases

The Departments of Pharmacology and Ophthalmology and Visual Sciences at Case Western Reserve University School of Medicine have been awarded a $10.1 million grant from the National Eye Institute (NEI) to research and develop new treatments for diseases of the retina, a leading cause of blindness.

29 Dec 2010

AMPK activates autophagy by activating ATG1 enzyme

Researchers at the Salk Institute for Biological Studies have discovered how AMPK, a metabolic master switch that springs into gear when cells run low on energy, revs up a cellular recycling program to free up essential molecular building blocks in times of need.

24 Dec 2010

Immunization with VLP vaccine results in functional, protective immune responses against RSV

Novavax, and scientists at the University of Massachusetts Medical School, led by Dr. Trudy Morrison, published in the January 2011 issue of The Journal of Virology, a report indicating that a novel virus-like particle vaccine candidate against respiratory syncytial virus (RSV) protects mice from a live virus challenge.

23 Dec 2010

Pregnant women veterans face increase risk of mental health problems

Pregnancy among women veterans who served in Iraq and Afghanistan appears to increase their risk for mental health problems such as depression, anxiety, and post-traumatic stress disorder, according to a study published in Journal of Women's Health, a peer-reviewed journal published by Mary Ann Liebert, Inc. The paper is available free online.

22 Dec 2010

Researchers develop new malaria vaccine strategy based on ingestion of genetically modified starch

Researchers from two laboratories in northern France have successfully vaccinated and protected mice by feeding them starch derived from green algae and genetically modified to carry vaccine proteins.

21 Dec 2010

Deinove to receive European patent for genetic engineering process

Deinove, the world's leading specialist in Deinococcus bacteria for biofuels, green chemistry and antibiotics, today announced that the European Patent Office had notified it of the intention to grant the patent application EP2016183 entitled "Process for chromosome engineering using a novel DNA repair system".

21 Dec 2010

Precise method to measure telomeres

Life Length, S.L. is a new biotechnology company set up to measure the length of telomeres which form caps at the end of chromosomes and that have a fundamental role in avoiding the break down and the aging of cells and organisms. The breakthroughs that Dr. Maria Blasco has made at the Spanish National Cancer Research Centre (Centro Nacional de Investigaciones Oncologicas, or CNIO) in Madrid, Spain form the founding basis of the company.

16 Dec 2010

New skincare product with cellular activators

Scientists in Iceland have developed a revolutionary skincare product after more than a decade of extensive research in plant biotechnology. The skin-rejuvenating phenomenon is called BIOEFFECT(TM) EGF Serum. Made by Sif Cosmetics, it is the world's first skincare product to contain cellular activators made in plants. Six months after its launch in Iceland, the serum is already being used by over 20% of Icelandic women.

15 Dec 2010

Researchers develop synthetic circuits to detect changes in state of health

Using yeast cells, a group of researchers at the University of Gothenburg, Sweden, has taken a groundbreaking step towards being able to build complex systems in the future where the body's own cells help to keep us healthy.

15 Dec 2010

Reversible two-step binding mechanism to stop cancer cell growth

What makes cancer cells so dangerous is that they grow in an unregulated way and proliferate much faster than other cells. The proteasome, a large protein complex, plays a key role in this process: By breaking down used proteins for recycling, it clears the way for the next cycle.

14 Dec 2010

Research programs embody the promise of anti-aging medicine.

Sometimes the value of research lies as much in exposing false remedies as in discovering true breakthroughs. Scientists at the country's first school of gerontology and in laboratories around the University of Southern California do both, mindful of their responsibility to a society focused on healthful aging.

13 Dec 2010

Horizon Discovery licenses new human isogenic cell models from Case Western Reserve

With the goal of developing new, more effective and personalized cancer treatments, Horizon Discovery, based in Cambridge, England, has secured from Case Western Reserve University exclusive rights to a panel of new human isogenic cell models developed by the laboratory of Zhenghe Wang, assistant professor of genetics at the university's School of Medicine.

10 Dec 2010

Horizon Discovery secures exclusive rights to human isogenic cell models

With the goal of developing new, more effective and personalized cancer treatments, Horizon Discovery, based in Cambridge, England, has secured from Case Western Reserve University exclusive rights to a panel of new human isogenic cell models developed by the laboratory of Zhenghe John Wang, assistant professor of genetics at the university's School of Medicine.

10 Dec 2010

Bacterium used to tackle Dengue fever

This January Australian scientists will start deploying a strange bacterium called Wolbachia pipientis in an attempt to halt disease transmission by mosquitoes especially Dengue fever. They are targeting the Aedes aegypti mosquito that transmits Dengue. Dengue is a viral disease that leads to high fever, severe muscle and joint pain and can also be fatal.

9 Dec 2010