Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

New regulatory mechanism could help develop novel therapies for cancer

Molecular microbiologists at the University of Southern California (USC) have uncovered intricate regulatory mechanisms within the cell that could lead to novel therapeutics for the treatment of cancer and other diseases.

23 Sep 2013

Researchers report encouraging results from T1DAL study on type 1 diabetes

Encouraging results from the T1DAL study (Targeting effector memory T cells with alefacept in new onset type 1 diabetes), led by Mark R. Rigby MD, PhD from Indiana University and Riley Hospital for Children in Indianapolis and sponsored by the Immune Tolerance Network (ITN) with additional support from JDRF, are published today in The Lancet Diabetes & Endocrinology.

23 Sep 2013

New study on propofol drug may help develop effective anesthetics with fewer side effects

Researchers at Washington University School of Medicine in St. Louis and Imperial College London have identified the site where the widely used anesthetic drug propofol binds to receptors in the brain to sedate patients during surgery.

23 Sep 2013

Research on synapse stabilization aids understanding of autism, schizophrenia, intellectual disability

When we're born, our brains aren't very organized. Every brain cell talks to lots of other nearby cells, sending and receiving signals across connections called synapses.

21 Sep 2013

Applied Integrin Sciences' drug candidate eliminates ovarian cancer tumors in pre-clinical study

Applied Integrin Sciences, Inc. announced today that its first cancer therapeutic drug candidate eliminated all intraperitoneal ovarian cancer tumors in a pre-clinical study testing a novel treatment regimen.

21 Sep 2013

Researchers make new breakthroughs in brain circuitry controlling fertility

In a landmark discovery, the final piece in the puzzle of understanding how the brain circuitry vital to normal fertility in humans and other mammals operates has been put together by researchers at New Zealand's University of Otago.

21 Sep 2013

New cellular switch could eventually inhibit growth of aggressive malignant brain tumor

Researchers at UT Southwestern Medical Center have identified a cellular switch that potentially can be turned off and on to slow down, and eventually inhibit the growth of the most commonly diagnosed and aggressive malignant brain tumor.

21 Sep 2013

Understanding tribological damage in biomaterials and medical implants

During their service life, most biomaterials and medical implants are vulnerable to tribological damage. In addition, the environments in which they are placed are often corrosive. The combination of triobology, corrosion and the biological environment has been named ‘bio-tribocorrosion’. Understanding this complex phenomenon is critical to improving the design and service life of medical implants. This important book reviews recent key research in this area.

20 Sep 2013

BASF Eyes Strategic Protein Growth, Buys Verenium For $62M

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20 Sep 2013

Antibody that binds, neutralizes HIV likely also targets the body's own self proteins

Researchers at The Scripps Research Institute discovered that an antibody that binds and neutralizes HIV likely also targets the body's own "self" proteins. This finding could complicate the development of HIV vaccines designed to elicit this protective antibody, called 4E10, and others like it, as doing so might be dangerous or inefficient.

20 Sep 2013

Small alteration in a brain gene contributes to risk for anxiety, depression and memory loss

Researchers at Weill Cornell Medical College have discovered why a tiny alteration in a brain gene, found in 20 percent of the population, contributes to the risk for anxiety, depression and memory loss.

20 Sep 2013

GW researcher awarded UO-1 grants to study gut microbiome on inflammation, cardiovascular disease

Dominic Raj, M.D., director of the division of nephrology and professor of medicine at the George Washington University School of Medicine and Health Sciences, was the recipient of two prestigious UO-1 grants from the National Institutes of Health.

20 Sep 2013

Dog food preservative may prevent nerve damage in patients taking chemotherapy

Working with cells in test tubes and in mice, researchers at Johns Hopkins have discovered that a chemical commonly used as a dog food preservative may prevent the kind of painful nerve damage found in the hands and feet of four out of five cancer patients taking the chemotherapy drug Taxol.

20 Sep 2013

Researchers discover new mechanism involving p53 to fight against aggressive cancers

Researchers at A*STAR's Singapore Immunology Network (SIgN) have discovered a new mechanism involving p53, the famous tumour suppressor, to fight against aggressive cancers.

20 Sep 2013

Protein pair may be prognostic biomarker for identifying smoking-related lung cancers

Mayo Clinic researchers have shown that a specific protein pair may be a successful prognostic biomarker for identifying smoking-related lung cancers. The protein — ASCL1 — is associated with increased expression of the RET oncogene, a particular cancer-causing gene called RET. The findings appear in the online issue of the journal Oncogene.

20 Sep 2013

Drexel University researchers create molecule that can cause AIDS virus to destroy itself

Pinning down an effective way to combat the spread of the human immunodeficiency virus, the viral precursor to AIDS, has long been challenge task for scientists and physicians, because the virus is an elusive one that mutates frequently and, as a result, quickly becomes immune to medication.

20 Sep 2013

Studies reveal functioning of nerve cells in entorhinal cortex

The entorhinal cortex is a link between the brain's memory centre, the hippocampus, and the other areas of the brain. It is, however, more than an interface that only transfers nervous impulses.

20 Sep 2013

Isis Pharmaceuticals announces preliminary data from ISIS-SMNRx Phase 1 study in infants with SMA

Isis Pharmaceuticals, Inc. announced today that follow-up preliminary data from a single dose, open-label Phase 1 study of ISIS-SMNRx in children with spinal muscular atrophy, show that most SMA children receiving the two highest doses of the drug (6 mg and 9 mg) continued to show improvements in muscle function tests up to 14 months after a single injection of the drug.

19 Sep 2013

Omeros announces initiation of enrollment in OMS824 Phase 2 trial for schizophrenia

Omeros Corporation today announced initiation of enrollment in a Phase 2 clinical trial of OMS824, the company's phosphodiesterase 10 inhibitor. The trial will evaluate the compound's tolerability, safety, pharmacokinetics, potential interactions with concomitant antipsychotic medications, and a battery of cognitive tests in patients with stable schizophrenia.

19 Sep 2013

Bugs may provide substantial solutions to some of life's problems

Bug spray, citronella candles, mosquito netting - most people will do anything they can to stay away from insects during the warmer months. But those creepy crawlers we try so hard to avoid may offer substantial solutions to some of life's problems.

19 Sep 2013

Protein News and Research

Further Reading

New regulatory mechanism could help develop novel therapies for cancer

Researchers report encouraging results from T1DAL study on type 1 diabetes

New study on propofol drug may help develop effective anesthetics with fewer side effects

Research on synapse stabilization aids understanding of autism, schizophrenia, intellectual disability

Applied Integrin Sciences' drug candidate eliminates ovarian cancer tumors in pre-clinical study

Researchers make new breakthroughs in brain circuitry controlling fertility

New cellular switch could eventually inhibit growth of aggressive malignant brain tumor

Understanding tribological damage in biomaterials and medical implants

BASF Eyes Strategic Protein Growth, Buys Verenium For $62M

Antibody that binds, neutralizes HIV likely also targets the body's own self proteins

Small alteration in a brain gene contributes to risk for anxiety, depression and memory loss

GW researcher awarded UO-1 grants to study gut microbiome on inflammation, cardiovascular disease

Dog food preservative may prevent nerve damage in patients taking chemotherapy

Researchers discover new mechanism involving p53 to fight against aggressive cancers

Protein pair may be prognostic biomarker for identifying smoking-related lung cancers

Drexel University researchers create molecule that can cause AIDS virus to destroy itself

Studies reveal functioning of nerve cells in entorhinal cortex

Isis Pharmaceuticals announces preliminary data from ISIS-SMNRx Phase 1 study in infants with SMA

Omeros announces initiation of enrollment in OMS824 Phase 2 trial for schizophrenia

Bugs may provide substantial solutions to some of life's problems

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