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Respira reports results of DPI drug engine clinical study against COPD, asthma

Respira Therapeutics, a product development company focused on inhaled therapeutics to improve patients' lives, today announced the results of a clinical feasibility study of the Company's drug engine technology.

21 Jun 2011

Positive results from Neurelis NRL-01 Phase 1 trial against epilepsy

Neurelis, Inc. today announced the results of a randomized crossover study in healthy volunteers assessing diazepam pharmacokinetics and bioavailability after administration of their proprietary intranasal diazepam formulations and intravenous injection.

15 Jun 2011

GE Healthcare announces results of Optison heart ultrasound contrast agent presented at ASE

Today, GE Healthcare Medical Diagnostics announced results of a study that evaluated the cardiopulmonary safety of Optison- (Perflutren Protein-Type A Microspheres Injectable Suspension, USP), a diagnostic ultrasound contrast agent for use in improving suboptimal echocardiograms.

14 Jun 2011

Frontal cerebral thermal transfer can eliminate insomnia symptoms

People with primary insomnia may be able to find relief by wearing a cap that cools the brain during sleep, suggests a research abstract that will be presented Monday, June 13, in Minneapolis, Minn., at SLEEP 2011, the 25th Anniversary Meeting of the Associated Professional Sleep Societies LLC (APSS).

13 Jun 2011

Hepatitis C virus (HCV)-associated liver disease after liver transplantation

Hepatitis C virus (HCV)-associated liver disease continues to be the most common indication for liver transplantation (LT) in the United States accounting for nearly 50% of all liver transplants. Recurrence is universal in patients viremic at the time of transplantation with histological hepatitis developing in the majority of patients. Although the natural history of recurrent HCV is difficult to predict, it is widely accepted that cirrhosis from recurrent HCV occurs in up to 30% of patients within five years of transplantation.

8 Jun 2011

MicroDose completes atropine inhaler Phase I study on nerve agent poisoning

MicroDose Therapeutx Inc. today announced that its collaborators at the University of Pittsburgh (Pitt) have completed a Phase I study at the University of Pittsburgh Medical Center with atropine sulfate delivered from the MicroDose proprietary dry powder inhaler (DPI).

8 Jun 2011

Positive results from Plexxikon's vemurafenib Phase 2 and 3 trial against metastatic melanoma

Plexxikon Inc., a member of the Daiichi Sankyo Group, today announced efficacy and safety data from the BRIM3 trial, a large, randomized, multi-center Phase 3 clinical study of vemurafenib in patients with previously untreated metastatic melanoma with the BRAFV600 mutation.

6 Jun 2011

AVEO’s ficlatuzumab-gefitinib Phase 1b/2 trial data against NSCLC to be presented at ASCO 2011

AVEO Pharmaceuticals, Inc. today announced results from the Phase 1b portion of its Phase 1b/2 clinical study of ficlatuzumab in combination with gefitinib in Asian subjects with non-small cell lung cancer.

2 Jun 2011

Somnus Therapeutics completes SKP-1041 Phase 2 trial against sleep maintenance insomnia

Somnus Therapeutics, Inc., a private specialty pharmaceutical company, has completed a Phase 2 dose-ranging study of SKP-1041, a modified-release formulation of zaleplon.

2 Jun 2011

New findings from STELARA psoriasis clinical trial to be presented at 22nd World Congress of Dermatology

New findings to be presented from pooled analyses of the STELARA psoriasis clinical development program showed that the safety profile of STELARA and rates of adverse events remained consistent and stable over time in adults with moderate to severe plaque psoriasis receiving up to four years of treatment.

25 May 2011

Low doses of natural Hi-maize resistant starch could improve insulin sensitivity in men at risk for prediabetes

Low doses of natural Hi-maize resistant starch could improve insulin sensitivity in men at risk for prediabetes, according to a study underwritten by National Starch LLC, a business unit of Corn Products International. The American Diabetes Association defines prediabetes as a non-disease state where blood sugar (glucose) levels are higher than normal, but not yet high enough to be diagnosed as diabetes.

23 May 2011

High heels and narrow toe boxes lead to toe deformities in women

According to a recent study, 39 percent of women say they wear high heels every day, and 75 percent of those women say they experience regular shoe-related foot pain and suffer from bunions, arthritic big toes, calluses, hammer toes, and plantar warts.

21 May 2011

Study links video game playing with increased food intake in kids

The US Centers for Disease Control and Prevention estimates that almost 18% of US teens are obese. Although most experts agree that our growing obesity "epidemic" is driven by both inadequate physical activity and excessive caloric intake, implementing solutions is extraordinarily difficult.

18 May 2011

Plexxikon seeks vemurafenib marketing approval from FDA and EMA for melanoma treatment

Plexxikon Inc., a member of the Daiichi Sankyo Group, today announced that applications for market approval for vemurafenib for the treatment of metastatic melanoma have been submitted to the U.S. Food and Drug Administration and the European Medicines Agency.

11 May 2011

Independent investigator begins pump trial of Biodel's two ultra-rapid human insulin formulations

Biodel Inc. announced today that an independent investigator initiated a pump trial of Biodel's two ultra-rapid-acting formulations of recombinant human insulin.

10 May 2011

Bayer's regorafenib granted FDA Fast Track designation for treatment of GIST

Bayer HealthCare Pharmaceuticals Inc. announced today that its investigational compound regorafenib (BAY 73-4506) has been granted Fast Track designation by the U.S. Food and Drug Administration for the treatment of patients with metastatic and/or unresectable gastrointestinal stromal tumors (GIST) whose disease has progressed despite at least imatinib and sunitinib as prior treatments.

10 May 2011

Researchers identify eight main triggers that appear to increase risk of brain aneurysm

From drinking coffee to having sex to blowing your nose, you could temporarily raise your risk of rupturing a brain aneurysm — and suffering a stroke, according to a study published in Stroke: Journal of the American Heart Association.

6 May 2011

Asthma ‘pill-a-day’ shows similar effectiveness as inhalers: Study

A new study has shown that a ‘once-a-day’ pill may be on par with an inhaler at combating asthma. This tablet, say researchers could revolutionize treatment for the condition, meaning patients are no longer reliant on inhalers, which many find difficult to use. Around 5.4 million Britons have asthma, including 1.1 million children.

5 May 2011

Softgels as effective as tablets in delivering folic acid

Folic acid, an essential vitamin formulated to be part of a multivitamin + DHA liquid softgel capsule, is absorbed and available within the body in amounts similar to folic acid formulated for solid tablets, according to a study presented in a late breaking session at the Experimental Biology (EB) 2011 annual meeting.

28 Apr 2011

Neurelis completes dosing in intranasal diazepam formulation study

Neurelis, Inc. today announced the completion of subject dosing in a randomized crossover study assessing diazepam pharmacokinetics and bioavailability after administration of two proprietary formulations of intranasal diazepam and intravenous injection.

21 Apr 2011