Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Mild to moderate COVID causes inflammation of white matter in brain ten months later

In a recent work published in the medRxiv* preprint server, scientists in Germany performed neuropsychological evaluations and brain imaging of people who recovered from mild to moderate coronavirus disease 2019 (COVID-19).

12 Jul 2022

Study finds microglia to be responsible for neuronal death in a mitochondrial disease animal model

Microglia, a type of central nervous system cell, is primarily responsible for neuronal death in Leigh Syndrome and the neurological symptoms related to this mitochondrial disease.

8 Jul 2022

Bone marrow transplants may be an effective treatment for ALS, research suggests

Along with the central nervous system, the immune system may play a fundamental role in Amyotrophic Lateral Sclerosis (ALS), suggesting that bone marrow transplants may be an effective novel treatment for the neurodegenerative disease.

6 Jul 2022

Gene defect underlying Krabbe disease causes degeneration of neurons directly, study finds

The gene defect underlying Krabbe disease causes degeneration of neurons directly, independent of its effects on other cell types, according to a new study publishing July 5th in the open-access journal PLOS Biology by Daesung Shin of the University at Buffalo, U.S. and colleagues.

5 Jul 2022

Comprehensive atlas of genetic data on zebrafish will benefit medical and life science researchers

Medical and life science researchers will benefit from the most comprehensive atlas yet of genetic data on zebrafish, newly published research suggests.

4 Jul 2022

Elevated cerebrospinal fluid biomarkers of neuroinflammation in NeuroCOVID patients

A new research paper studied several biomarkers associated with neuronal injury, neuroinflammation, and neurodegeneration in NeuroCOVID adults who experienced a CNS syndrome during acute SARS-CoV-2 infection.

4 Jul 2022

Brain immune response to SARS-CoV-2 infection

In a recently published article in the journal Current Opinion in Neurobiology, scientists at Washington University School of Medicine, St. Louis have described how immunological alterations associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may impact brain activities and induce acute and post-acute neurological symptoms in coronavirus disease 2019 (COVID-19) patients.

3 Jul 2022

Duke researchers identify role for key gene in developmental disability syndrome

A single gene that was previously found to be the driving force in a rare syndrome linked to epilepsy, autism and developmental disability has been identified as a linchpin in the formation of healthy neurons.

28 Jun 2022

Canadian Consortium on Neurodegeneration in Aging launches an online program to prevent dementia

Canada's largest dementia research initiative, the Canadian Consortium on Neurodegeneration in Aging (CCNA), has launched an innovative online program that offers older adults the opportunity to increase their knowledge of dementia, improve lifestyle risk factors and engage with researchers.

27 Jun 2022

Nearly all known biological pathways in the brain are linked to Alzheimer's disease

Nearly six million older adults have Alzheimer's disease in the United States, a number expected to double by 2050.

24 Jun 2022

U-M researchers reveal how a mutated protein acts as risk factor in Parkinson’s disease

In about a fifth of the cases of Parkinson’s disease, look to a small, malfunctioning protein in the lysosome as a risk factor, say University of Michigan researchers.

23 Jun 2022

Immune and central nervous systems may play a key role in ALS, Mount Sinai researchers report

The immune system may play a fundamental role along with the central nervous system in amyotrophic lateral sclerosis (ALS), also known as "Lou Gehrig's disease," Mount Sinai researchers report.

22 Jun 2022

Association of neuronal and non-neuronal GABA with neuropsychiatric illness in COVID-19 patients

A new study published in the journal Reports focused on the hijacking of the pancreatic, endothelial, and gut GABA by SARS-CoV-2 and its associated pathology along with interventions.

10 Jun 2022

Cryo-EM helps scientists to decipher the structure of a key part of RNA degradation machinery

In biology, getting rid of stuff can be just as important as making it. A buildup of cells, proteins, or other molecules that are no longer needed can cause problems, so living things have evolved several ways to clean house.

9 Jun 2022

Targeting fatty acid metabolism holds promise for Parkinson's disease

The human brain is lipid rich. Lipids and fatty acids contribute to many important cellular processes. Alpha-synuclein -; a protein that plays a critical role in Parkinson's disease (PD) -; is known to interact with and alter the balance of lipids and fatty acids.

9 Jun 2022

Einstein researchers receive $3.5 million NIH grant to study the effects of SARS-CoV-2 on the brain

Albert Einstein College of Medicine researchers have been awarded a five-year, $3.5 million grant from the National Institutes of Health to study the effects of COVID-19 on the brains of adults who had mild or asymptomatic infection.

8 Jun 2022

Truncated tau protein may be a means for better diagnosis and treatment of Alzheimer's disease

In a new study of Alzheimer's disease, researchers at UC San Francisco have discovered that a relatively unstudied form of the tau protein associated with neurodegeneration may be a means for better diagnosis and treatment of the disease.

2 Jun 2022

Membrane lipid stops stress reactions and inhibits cell death

Programmed cell death is an important tool that an organism uses to keep itself healthy. When a cell does not function as it should, various stress reactions are activated. The goal of these reactions is to restore the original cell function.

1 Jun 2022

Using diffusion-weighted MRI to visualize brain inflammation in vivo for the first time

Research of the laboratories led by Dr. Silvia de Santis and Dr. Santiago Canals, both from the Institute of Neurosciences UMH-CSIC (Alicante, Spain), has made it possible to visualize for the first time and in great detail brain inflammation using diffusion-weighted Magnetic Resonance Imaging.

27 May 2022

Normal brain aging accelerated by 26% in people with progressive type 2 diabetes, study shows

Scientists have demonstrated that normal brain aging is accelerated by approximately 26% in people with progressive type 2 diabetes compared with individuals without the disease, reports a study published today in eLife.

24 May 2022