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Study may provide novel targetable mechanisms of therapeutic resistance to anti-VEGF therapies

To establish a molecular signature of this resistance in ovarian cancer, the authors developed preclinical tumor models of adaptive resistance to chronic anti-VEGF treatment.

8 Jan 2020

Nicotine concentrations found to be higher from JUUL pods than e-cigs and cigarettes

JUUL delivers substantially more nicotine to the blood per puff than cigarettes or previous-generation e-cigarettes (e-cigs) and impairs blood vessel function comparable to cigarette smoke, according to a new study by researchers at UC San Francisco.

6 Jan 2020

Long-term consumption of lingonberry juice lowers high blood pressure, study finds

An experimental study found that long-term consumption of lingonberry juice lowers high blood pressure and improves the function of blood vessels.

3 Jan 2020

First reported occurrence and treatment of venous thrombosis during spaceflight

Serena Auñón-Chancellor, M.D., M.P.H., Clinical Associate Professor of Medicine at LSU Health New Orleans School of Medicine's branch campus in Baton Rouge, is the lead author of a paper describing a previously unrecognized risk of spaceflight discovered during a study of astronauts involved in long-duration missions.

2 Jan 2020

Early modern humans in southern Africa cooked starchy plants 170 thousand years ago

"The inhabitants of the Border Cave in the Lebombo Mountains on the Kwazulu-Natal/eSwatini border were cooking starchy plants 170 thousand years ago," says Professor Lyn Wadley, a scientist from the Wits Evolutionary Studies Institute at the University of the Witwatersrand, South Africa.

2 Jan 2020

Mount Sinai awarded more than $10 million in federal funding for research on glioblastoma

The Department of Neurosurgery at the Icahn School of Medicine at Mount Sinai has received more than $10 million in federal funding for several projects focusing on brain tumor research.

2 Jan 2020

Tau-protein better predicts brain atrophy in Alzheimer's patients than amyloid plaques

Brain imaging of pathological tau-protein "tangles" reliably predicts the location of future brain atrophy in Alzheimer's patients a year or more in advance, according to a new study by scientists at the UC San Francisco Memory and Aging Center. In contrast, the location of amyloid "plaques," which have been the focus of Alzheimer's research and drug development for decades, was found to be of little utility in predicting how damage would unfold as the disease progressed.

2 Jan 2020

Obj-SCD predicts future amyloid accumulation and neurodegeneration

Writing in the December 30, 2019 online issue of Neurology, researchers at University of California San Diego School of Medicine and Veterans Affairs San Diego Healthcare System report that accumulating amyloid -- an abnormal protein linked to neurodegenerative conditions such as Alzheimer's disease -- occurred faster among persons deemed to have "objectively-defined subtle cognitive difficulties" (Obj-SCD) than among persons considered to be "cognitively normal."

31 Dec 2019

A HSC surface marker plays key role in ontogeny of hematopoiesis

A group of researchers at Osaka University revealed that ESAM (Endothelial cell-selective adhesion molecule), a surface marker for hematopoietic stem cells (HSCs) and vascular endothelial cells (ECs), played an important role in the ontogeny of hematopoiesis in mice, particularly in the development of adult-type erythropoiesis.

26 Dec 2019

Common cardiac blood test before surgery can predict post-operative complications

A common cardiac blood test done before surgery can predict who will experience adverse outcomes after most types of surgery, says an international study led by Hamilton researchers.

23 Dec 2019

Sphingotec's new biomarker bio-ADM identifies ICU patients who need immediate organ support

Diagnostics company SphingoTec GmbH today announced a publication in Critical Care1 with data on 2,000 ICU patients demonstrating that sphingotec's proprietary biomarker bio-ADM (Bioactive Adrenomedullin) not only identifies high-risk patients for septic shock at admission but also identifies patients in the general ICU patient population who require immediate life-saving therapeutic intervention.

23 Dec 2019

Government-funded day care helps keep seniors out of nursing homes and hospitals

Two mornings a week, a van arrives at the Escondido, Calif., home of Mario Perez and takes him to a new senior center in this northern San Diego County town, where he eats a hot lunch, plays cards and gets physical therapy to help restore the balance he lost after breaking both legs in a fall.

23 Dec 2019

Scientists identify molecular mechanisms that protect cells against mechanical stress

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified the molecular mechanisms that allow our cells to adapt to, protect themselves against, and survive mechanical stress.

20 Dec 2019

Canadian First Nations communities with greater social support, trust have lower cardiac risk factors

A major study has found that Canadian First Nations communities with greater socio-economic advantages, educational opportunities, social support of family members and greater trust between community members, have lower cardiac risk factors.

19 Dec 2019

Routine cardiac stress test turns into lifesaving gift

Erika Hosey, a cardiovascular technician at University Hospitals Ahuja Medical Center, ended the year by giving a life-changing gift to a patient in need. While performing a routine cardiac stress test, she drummed up a conversation. She learned that her patient, Denise Butvin, had kidney disease and needed transplant surgery.

19 Dec 2019

Pilot study shows strong results for genicular artery embolization to treat OA-related knee pain

A new study published in Journal of Vascular and Interventional Radiology details the first study of its kind in the U.S. to examine the use of genicular artery embolization (GAE) for extended treatment of knee pain caused by osteoarthritis.

17 Dec 2019

Researchers identify novel genetic signature with prognostic value for certain breast cancers

Researchers have identified a genetic signature with prognostic value for certain kinds of breast cancer. The discovery also contributes to a better understanding of the molecular mechanisms of pathological angiogenesis, the aberrant proliferation of blood vessels that occurs during cancer and other diseases.

17 Dec 2019

Brazilian researchers create hepatic organoids by 3D bioprinting

Using human blood cells, Brazilian researchers have succeeded in obtaining hepatic organoids ("mini-livers") that perform all of the liver's typical functions, such as producing vital proteins, storing vitamins, and secreting bile, among many others.

17 Dec 2019

Heart-healthy diet is low in cholesterol, says AHA yet again

A news release from the American Health Association (AHA) in the form of a Scientific Advisory, published in the journal Circulation on December 16, 2019, reiterates that replacing saturated fat with polyunsaturated fats is an effective way to keep the arteries healthy by lowering the levels of artery-clogging cholesterol (LDL) in blood.

16 Dec 2019

Super-resolution localization photoacoustic microscopy can find blocked or burst blood vessels

200 years ago, a doctor from France used a stethoscope for the first time and countless efforts to observe human body have been made since then. Up to now, the best tool that provides anatomical, functional, and molecular information of human and animal is the photoacoustic microscopy.

16 Dec 2019

Vascular News and Research

Study may provide novel targetable mechanisms of therapeutic resistance to anti-VEGF therapies

Nicotine concentrations found to be higher from JUUL pods than e-cigs and cigarettes

Long-term consumption of lingonberry juice lowers high blood pressure, study finds

First reported occurrence and treatment of venous thrombosis during spaceflight

Early modern humans in southern Africa cooked starchy plants 170 thousand years ago

Mount Sinai awarded more than $10 million in federal funding for research on glioblastoma

Tau-protein better predicts brain atrophy in Alzheimer's patients than amyloid plaques

Obj-SCD predicts future amyloid accumulation and neurodegeneration

A HSC surface marker plays key role in ontogeny of hematopoiesis

Common cardiac blood test before surgery can predict post-operative complications

Sphingotec's new biomarker bio-ADM identifies ICU patients who need immediate organ support

Government-funded day care helps keep seniors out of nursing homes and hospitals

Scientists identify molecular mechanisms that protect cells against mechanical stress

Canadian First Nations communities with greater social support, trust have lower cardiac risk factors

Routine cardiac stress test turns into lifesaving gift

Pilot study shows strong results for genicular artery embolization to treat OA-related knee pain

Researchers identify novel genetic signature with prognostic value for certain breast cancers

Brazilian researchers create hepatic organoids by 3D bioprinting

Heart-healthy diet is low in cholesterol, says AHA yet again

Super-resolution localization photoacoustic microscopy can find blocked or burst blood vessels

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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