Laboratory News and Research

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Breakthrough in stem cell research

Dutch researchers at University Medical Center Utrecht and the Hubrecht Institute have succeeded in growing large numbers of stem cells from adult human hearts into new heart muscle cells.

23 Apr 2008

Menstrual blood - an abundant sources of stem cells

Researchers seeking new and more abundant sources of stem cells for use in regenerative medicine have identified a potentially unlimited, noncontroversial, easily collectable, and inexpensive source - menstrual blood.

23 Apr 2008

NIH study reveals incidence, precursors and psychiatric sequelae of major psychiatric disorders

A new study by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) presents results on the first onset of substance use disorders (i.e., alcohol and drug abuse and dependence) and major mood and anxiety disorders, based on Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC).

22 Apr 2008

Red colobus monkeys in Uganda found to harbor antibodies to an unknown orthopoxvirus

Researchers report this month that red colobus monkeys in a park in western Uganda have been exposed to an unknown orthopoxvirus, a pathogen related to the viruses that cause smallpox, monkeypox and cowpox. Most of the monkeys screened harbor antibodies to a virus that is similar - but not identical - to known orthopoxviruses.

22 Apr 2008

Scientists solve mystery about critical mechanism of gene expression

Although letters representing the three billion pairs of molecules that form the "rungs" of the helical DNA "ladder" are routinely called the human "genetic code," the DNA they comprise transmits traits across generations in a variety of ways, not all of which depend on the sequence of letters in the code.

22 Apr 2008

Mechanism discovered that can send cells on the road to cancer

Using a common virus as a tool for investigating abnormal cell proliferation, a team led by scientists at Cold Spring Harbor Laboratory (CSHL) has succeeded in clarifying an intricate series of biochemical steps that shed light on a way that cancer can begin.

22 Apr 2008

New advance in use of oncolytic viruses as novel cancer treatments

Combining a herpes virus genetically altered to express a drug-enhancing enzyme with a chemotherapy drug effectively and safely reduced the size of highly malignant human sarcoma grafted into mice.

22 Apr 2008

Severe acute watery diarrhoea with Vibrio cholerae positive cases in Vietnam

Between 5 March and 22 April the Ministry of Health of Vietnam reported 2,490 cases of severe acute watery diarrhoea including 377 that were positive for Vibrio cholerae, the bacterium causing cholera.

22 Apr 2008

Discovery of gene that may influence metastasis risk in breast cancer

Researchers have identified a pattern of gene activity in mice that may help to predict individual risk for breast cancer metastasis and survival in humans. A single gene, called bromodomain 4 (Brd4), regulates the expression of this pattern, also called a signature.

22 Apr 2008

Developing 'roadmaps' for enhancing the professional culture of medical schools

There is change afoot in the way medicine is being taught. Rigorous course work, state of the art laboratories and demanding clinical training are necessarily at the forefront. To complement the constant updating of the technical preparation of future physicians, a movement is growing determined to produce doctors who are not only outstanding clinicians, but who are also compassionate individuals able to communicate well with patients, their families and other caregivers.

22 Apr 2008

Chronic inflammation triggers cell fusions that could protect neurons

Chronic inflammation triggers bone marrow-derived blood cells to travel to the brain and fuse with a certain type of neuron up to 100 times more frequently than previously believed, according to a new study from the Stanford University School of Medicine.

20 Apr 2008

Biomoda granted 'notice of allowance' for U.S. patent protection for additional IP

Biomoda, Inc., a development stage medical diagnostics company, announced it has been granted a notice of allowance from the U.S. Patent and Trademark Office for its invention directed to the "Method for Prognosing Response to Cancer Therapy with 5,10,15,20-Tetrakis (Carboxyphenyl) Porphine."

18 Apr 2008

Constraint induced therapy causes increase in gray matter

A rehabilitation therapy developed by a UAB (University of Alabama at Birmingham) neuroscientist produces changes in the structure of the brain, the first evidence of actual brain remodeling resulting from a rehabilitation therapy.

17 Apr 2008

Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases

Many people take antioxidants in the belief that they will prolong their life expectancy. However, data from 67 randomised trials that involved just under a quarter of a million people failed to support this idea, a Cochrane Systematic Review has discovered.

17 Apr 2008