Neurons News and Research

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Sophisticated stem cell model reveals potential route of SARS-CoV-2 entry into the brain

Researchers at University of California San Diego School of Medicine and Rady Children's Institute for Genomic Medicine have produced a stem cell model that demonstrates a potential route of entry of SARS-CoV-2, the virus that causes COVID-19, into the human brain.

16 Jul 2021

Gene therapy delivered into the brain may be safe, effective in treating rare neurological disorder

A new study published in Nature Communications suggests that gene therapy delivered into the brain may be safe and effective in treating aromatic L-amino acid decarboxylase (AADC) deficiency.

16 Jul 2021

Scientists decipher the activity of the brain in deep sleep

Thanks to a unique system that decodes brain activity during sleep, a UNIGE team is deciphering the neuronal mechanisms of memory consolidation.

16 Jul 2021

Autophagy disruption may be at the root of early cognitive changes in Huntington’s disease

Huntington's Disease (HD) is a progressive neurodegenerative condition characterized by motor, cognitive, and psychiatric symptoms, and motor symptoms are often preceded by cognitive changes.

15 Jul 2021

Research sheds light on a new mechanism for inhibitory synapse specificity in the cortex

Researchers at the Max Planck Florida Institute for Neuroscience have discovered that the cell adhesion protein IgSF11 determines the layer-specific synaptic connectivity of a distinct class of cortical interneurons.

15 Jul 2021

Research finds Cannabis terpenes as a promising new target for pain therapies

When it comes to the medicinal and therapeutic properties of Cannabis sativa, an unsolved mystery is whether there exists an "entourage effect," whereby the pain-relieving effects of the plant as a whole are greater than any of its individual parts.

14 Jul 2021

Component derived from turmeric essential oil exhibits neuroprotective effects

Researchers from Kumamoto University, Japan have found that a component derived from turmeric essential oil, aromatic turmerone (ar-turmerone), and its derivatives act directly on dopaminergic nerves to create a neuroprotective effect on tissue cultures of a Parkinson's disease model.

14 Jul 2021

Sleep twitches guide metamorphosis of motor cortex in rats

Electrical activity in the motor cortex of rats transforms from redundant to complex over the span of four days shortly after birth. Sleep twitches guide this metamorphosis, according to new research published in JNeurosci.

14 Jul 2021

Bacteroides-dominant gut microbiome linked with advanced cognition and language skills in infant boys

The University of Alberta-led research followed more than 400 infants from the CHILD Cohort Study (CHILD) at its Edmonton site. Boys with a gut bacterial composition that was high in the bacteria Bacteroidetes at one year of age were found to have more advanced cognition and language skills one year later. The finding was specific to male children.

13 Jul 2021

UT Austin statisticians develop new way to model how the brain learns language

A cross-disciplinary team including University of Texas at Austin statisticians Giorgio Paulon and Abhra Sarkar have received the Mitchell Prize, a top prize in the field, for their study modeling what happens in the brains of nonnative English speakers learning another language's tonal differences.

13 Jul 2021

Gene therapy shows promise in children with devastating genetic disorder

Children with a devastating genetic disorder characterized by severe motor disability and developmental delay have experienced sometimes dramatic improvements in a gene therapy trial launched at UCSF Benioff Children's Hospitals.

12 Jul 2021

Modular network organization critical for persistent neural activity and brain communication

Recall a phone number or directions just recited and your brain will be actively communicating across many regions. It is thought that working memory relies on interactions between these regions, but how these brain areas interact and properly represent memory has remained a mystery.

12 Jul 2021

Researchers discover new genetic driver of autism and other developmental disorders

A research group including Kobe University's Professor TAKUMI Toru (also a Senior Visiting Scientist at RIKEN Center for Biosystems Dynamics Research) and Assistant Professor TAMADA Kota, both of the Physiology Division in the Graduate School of Medicine, has revealed a causal gene (Necdin, NDN) in autism model mice that have the chromosomal abnormality called copy number variation.

9 Jul 2021

Malfunction in the cell’s powerhouse causes sporadic Parkinson disease

The major cause of Parkinson’s Disease is a dysregulation of immune genes central for fighting against viruses, a new study reveals.

9 Jul 2021

Non-toxic derivative of tetanus neurotoxin may help treat depression, neurodegenerative diseases

Depression has been treated traditionally with inhibitors of serotonin reuptake in the central nervous system.

9 Jul 2021

Research can contribute to earlier diagnosis of diabetic neuropathy

Research conducted at Cruzeiro do Sul University in São Paulo, Brazil, can contribute to earlier diagnosis of diabetic neuropathy, a disorder characterized by damage to peripheral nerves, with symptoms such as pain and paresthesia (pricking, burning and numbness), mainly in the legs and feet.

7 Jul 2021

Study: Gene editing therapy for early-stage Huntington’s disease may have long-lasting benefits

In a new study on mice, Johns Hopkins Medicine researchers report that using MRI scans to measure blood volume in the brain can serve as a noninvasive way to potentially track the progress of gene editing therapies for early-stage Huntington's disease, a neurodegenerative disorder that attacks brain cells.

7 Jul 2021

Researchers identify early functional deficiencies in neurons derived from Parkinson's patients

Researchers from IDIBELL and the University of Barcelona have described that neurons derived from Parkinson's patients show impairments in their transmission before neurodegeneration.

7 Jul 2021

New technique provides deep tissue high-resolution images 100 to 1,000 times faster than other techniques

The new system, identified as DEEP, overcomes previous challenges with deep tissue microscopy and may revolutionize imaging methodology.

7 Jul 2021

Study identifies specialized immune cells that sculpt inhibitory neurons to regulate brain wiring

From the bark of a puppy to the patter of rain against the window, our brains receive countless signals every second. Most of the time, we tune out inconsequential cues--the buzz of a fly, the soft rustle of leaves in the tree--and pay attention to important ones--the sound of a car horn, a bang on the door.

7 Jul 2021

Neurons News and Research

Sophisticated stem cell model reveals potential route of SARS-CoV-2 entry into the brain

Gene therapy delivered into the brain may be safe, effective in treating rare neurological disorder

Scientists decipher the activity of the brain in deep sleep

Autophagy disruption may be at the root of early cognitive changes in Huntington’s disease

Research sheds light on a new mechanism for inhibitory synapse specificity in the cortex

Research finds Cannabis terpenes as a promising new target for pain therapies

Component derived from turmeric essential oil exhibits neuroprotective effects

Sleep twitches guide metamorphosis of motor cortex in rats

Bacteroides-dominant gut microbiome linked with advanced cognition and language skills in infant boys

UT Austin statisticians develop new way to model how the brain learns language

Gene therapy shows promise in children with devastating genetic disorder

Modular network organization critical for persistent neural activity and brain communication

Researchers discover new genetic driver of autism and other developmental disorders

Malfunction in the cell’s powerhouse causes sporadic Parkinson disease

Non-toxic derivative of tetanus neurotoxin may help treat depression, neurodegenerative diseases

Research can contribute to earlier diagnosis of diabetic neuropathy

Study: Gene editing therapy for early-stage Huntington’s disease may have long-lasting benefits

Researchers identify early functional deficiencies in neurons derived from Parkinson's patients

New technique provides deep tissue high-resolution images 100 to 1,000 times faster than other techniques

Study identifies specialized immune cells that sculpt inhibitory neurons to regulate brain wiring

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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