Laboratory News and Research

RSS

Targeting aggressive breast cancers by putting them to sleep

It is well established that Id1, a gene normally produced only in embryonic development, is reactivated in many 'solid' cancers, or carcinomas.

26 Mar 2008

Wistar Institute shares cell lines

Cell lines developed by scientists at The Wistar Institute in Philadelphia have recently been made available to researchers around the globe through the catalog collection at the Coriell Institute for Medical Research of Camden, N.J.

26 Mar 2008

Red wine antioxidant resveratrol kills cancer

Rochester researchers showed for the first time that a natural antioxidant found in grape skins and red wine can help destroy pancreatic cancer cells by reaching to the cell's core energy source, or mitochondria, and crippling its function.

26 Mar 2008

Discovery about fertilization points way to possible malaria vaccine

International investigations of an organism that one UT Southwestern Medical Center researcher calls a “silly little green scum” have led to key insights into the basic mechanisms of reproduction.

26 Mar 2008

A biosensing nanodevice to revolutionize health screenings

One day soon a biosensing nanodevice developed by Arizona State University researcher Wayne Frasch may eliminate long lines at airport security checkpoints and revolutionize health screenings for diseases like anthrax, cancer and antibiotic resistant Staphylococcus aureus (MRSA).

26 Mar 2008

Microbes in the guts of carpenter ants could lead to better drugs

Scientists have discovered two key proteins that guide one of the two groups of pathogenic bacteria to make their hardy outer shells -- their defense against the world.

26 Mar 2008

How Staphylococcus aureus resists our natural defenses

Researchers at the University of Washington have uncovered how the bacterium Staphylococcus aureus, including the notorious MRSA (methicillin-resistant Staph aureus) "superbug" strains, resists our body's natural defenses against infection.

25 Mar 2008

REST protein protects embryonic stem cells' versatility and self-renewal

A protein known as REST blocks the expression of a microRNA that prevents embryonic stem cells from reproducing themselves and causes them to differentiate into specific cell types, scientists at The University of Texas M. D. Anderson Cancer Center report in the journal Nature.

25 Mar 2008

Experimental drug SGX393 offers new approach to help control drug resistance in leukemia

Oregon Health & Science University Cancer Institute researchers have found that an experimental drug known as SGX393 is effective against Gleevec-resistant chronic myeloid leukemia (CML).

25 Mar 2008

Mutant proteins could lead to new treatment for heart disease

Heart damage due to blocked arteries remains the leading cause of disease and death in the Western world, but a Florida State University College of Medicine researcher is helping to open new pathways toward treating the problem.

25 Mar 2008

MRI opens up promising new avenues for non-invasive diagnoses and classification of cancer

Doctors diagnose and prescribe treatment for brain tumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or surgery.

25 Mar 2008

Researchers reveal hidden properties of an on-off switch that governs cell growth

Investigators at the Duke Institute for Genome Sciences and Policy have revealed the hidden properties of an on-off switch that governs cell growth.

25 Mar 2008

Typhoid no longer an enemy of the past as study highlights risk for travellers to indian sub-continent

UK travellers visiting friends and relatives on the Indian sub-continent are carrying an unnecessary burden of typhoid and paratyphoid (also called enteric fevers), according to researchers at the Health Protection Agency.

24 Mar 2008

PharmAthene signs agreement to acquire biodefense vaccines business from Avecia

PharmAthene, Inc., a biodefense company specializing in the development and commercialization of medical countermeasures against biological and chemical threats, and Avecia Biologics Limited, a contract manufacturer of biopharmaceuticals, has announced that the companies have entered into a definitive sale and purchase agreement under which PharmAthene will acquire all of the assets and intellectual property related to Avecia's biodefense vaccines business.

24 Mar 2008

New insight into radiation damage to DNA

A new technique for assessing the damage radiation causes to DNA indicates that the spatial arrangement of damaged sites, or lesions, is more important than the number of lesions in determining the severity of the damage.

24 Mar 2008

EpiCept announces opinion by European Regulatory Authority on Ceplene

EpiCept Corporation has announced that the European Committee for Medicinal Products for Human Use (CHMP), the scientific committee of the European Medicines Agency (EMEA), has issued, as expected following the trend vote announced last month, a negative opinion regarding the marketing authorization application (MAA) for Ceplene (histamine dihydrochloride) for the remission maintenance and prevention of relapse of patients with Acute Myeloid Leukemia (AML) in first remission.

24 Mar 2008

Brains are hardwired to act according to the Golden Rule

Wesley Autrey, a black construction worker, a Navy veteran and 55-year-old father of two, didn't know the young man standing beside him.

24 Mar 2008

A polyphenols-rich diet keeps the heart younger

This finding comes out from a study by the University of Grenoble in collaboration with the other Centres participating to the FLORA Project, a European Commission funded research studying the effects of flavonoids, a variety of polyphenols, on human health.

24 Mar 2008