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Novel approach for imaging immune cell movements identifies initial steps in inflammatory arthritis

Using a novel approach for imaging the movement of immune cells in living animals, researchers from the Massachusetts General Hospital Center for Immunology and Inflammatory Diseases have identified what appear to be the initial steps leading to joint inflammation in a model of inflammatory arthritis.

20 Jan 2017

Exeter scientists discover how two cell organelles interact at molecular level

Scientists have made a breakthrough in understanding how different compartments (or organelles) of human cells interact.

20 Jan 2017

MGH-developed CTC-iChip with digital PCR assay improves detection of early-stage liver cancer

Use of an advanced form of the commonly used polymerase chain reaction (PCR) method to analyze circulating tumor cells (CTCs) may greatly increase the ability to diagnose early-stage cancer, increasing the likelihood of successful treatment.

20 Jan 2017

Scientists harness rabies viruses for assessing connectivity of nerve cell transplants

Scientists under the leadership of the University of Bonn have harnessed rabies viruses for assessing the connectivity of nerve cell transplants: coupled with a green fluorescent protein, the viruses show where replacement cells engrafted into mouse brains have connected to the host neural network.

19 Jan 2017

Study shows structural impact of membrane lipids on medically relevant serotonin transporters

Neurotransmitter transporters are some of the most popular transport proteins in research as they play a major role in the processing of signals in the brain. A joint study by TU Wien and the Medical University of Vienna has now successfully demonstrated for the first time the structural impact of membrane lipids on medically relevant serotonin transporters.

19 Jan 2017

Research finding provides new target for regulating cell division

Modern genome sequencing methods used to measure the efficiency of synthesis of individual protein during cell division has found that the enzymes that make lipids and membranes were synthesized at much greater efficiency when a cell is ready to split.

19 Jan 2017

Blocking molecular signaling pathway could prevent or reverse peripheral neuropathy

Researchers at University of California San Diego School of Medicine, with colleagues at the National Institute of Diabetes and Digestive and Kidney Diseases, the University of Manitoba and St. Boniface Hospital Albrechtsen Research Centre in Canada, have identified a molecular signaling pathway that, when blocked, promotes sensory neuron growth and prevents or reverses peripheral neuropathy in cell and rodent models of type 1 and 2 diabetes, chemotherapy-induced neuropathy and HIV.

18 Jan 2017

Penn researchers discover antimicrobial that thwarts Zika viral entry into human cells

A panel of small molecules that inhibit Zika virus infection, including one that stands out as a potent inhibitor of Zika viral entry into relevant human cell types, was discovered by researchers from the Perelman School of Medicine at the University of Pennsylvania.

17 Jan 2017

Penn Vet researchers identify potential target to fight against Ebola

Viruses and their hosts are in a eternal game of one-upmanship. If a host cell evolves a way to stop a virus from spreading, the virus will look for a new path. And so on and so forth.

12 Jan 2017

Study identifies high levels of aluminium in the brains of familial Alzheimer's disease victims

A recently published study of the brains of familial Alzheimer's disease victims has found extremely high levels of aluminium in the tissue, announced Dr. Christopher Exley, researcher and professor at Keele University.

12 Jan 2017

Real-time study of medaka fish aboard ISS sheds light on bone metabolism under microgravity

Tokyo Institute of Technology research: Gravitational biology: Real time imaging and transcriptome analysis of medaka aboard space station

11 Jan 2017

New inverted microscope platform for life science research

Today, ZEISS introduces a new inverted microscope platform for life science research. The ZEISS Axio Observer family consists of three stable and modular microscope stands for flexible and efficient imaging. Scientists benefit from reproducible results from their experiments and high quality image data from a whole range of samples in a variety of conditions. ZEISS Axio Observer combines the proven quality of ZEISS optics with new automation features, allowing researchers to perform demanding multimodal imaging of living and fixed specimens.

10 Jan 2017

Cell powerhouses may be good therapeutic target for brain injury

Cell powerhouses are typically long and lean, but with brain injury such as stroke or trauma, they can quickly become bloated and dysfunctional, say scientists who documented the phenomena in real time for the first time in a living brain.

10 Jan 2017

Researchers find high-resolution structure of immature Zika virus

Researchers at Purdue University have determined the high-resolution structure of immature Zika virus, a step toward better understanding how the virus infects host cells and spreads.

10 Jan 2017

Study offers new insights into mechanisms underlying action of motor proteins

A study published today offers a new understanding of the complex cellular machinery that animal and fungi cells use to ensure normal cell division, and scientists say it could one day lead to new treatment approaches for certain types of cancers.

4 Jan 2017

TSRI researchers develop new approach to find how environmental estrogens impact public health

Breast cancer researchers from the Florida campus of The Scripps Research Institute have developed a novel approach for identifying how chemicals in the environment—called environmental estrogens—can produce infertility, abnormal reproductive development, including “precocious puberty,” and promote breast cancer.

3 Jan 2017

TSRI scientists develop new approach for understanding diverse effects of endocrine-disruptors

Breast cancer researchers from the Florida campus of The Scripps Research Institute (TSRI) have developed a novel approach for identifying how chemicals in the environment--called environmental estrogens--can produce infertility, abnormal reproductive development, including "precocious puberty," and promote breast cancer.

30 Dec 2016

Study suggests new options for improving cancer immunotherapy

One of the main reasons cancer remains difficult to treat is that cancer cells have developed a multitude of mechanisms that allow them to evade destruction by the immune system.

30 Dec 2016

Acute stress can lead to delayed, long-term psychological trauma

Mrs. M would never forget that day. She was walking along a busy road next to the vegetable market when two goons zipped past on a bike. One man's hand shot out and grabbed the chain around her neck.

30 Dec 2016

Super-resolution fluorescence microscopy sheds light on brain’s molecular mechanism

Advances in microscopy techniques have often triggered important discoveries in the field of neuroscience, enabling vital insights in understanding the brain and promising new treatments for neurodegenerative diseases such as Alzheimer's and Parkinson's.

29 Dec 2016

Microscopy News and Research

Novel approach for imaging immune cell movements identifies initial steps in inflammatory arthritis

Exeter scientists discover how two cell organelles interact at molecular level

MGH-developed CTC-iChip with digital PCR assay improves detection of early-stage liver cancer

Scientists harness rabies viruses for assessing connectivity of nerve cell transplants

Study shows structural impact of membrane lipids on medically relevant serotonin transporters

Research finding provides new target for regulating cell division

Blocking molecular signaling pathway could prevent or reverse peripheral neuropathy

Penn researchers discover antimicrobial that thwarts Zika viral entry into human cells

Penn Vet researchers identify potential target to fight against Ebola

Study identifies high levels of aluminium in the brains of familial Alzheimer's disease victims

Real-time study of medaka fish aboard ISS sheds light on bone metabolism under microgravity

New inverted microscope platform for life science research

Cell powerhouses may be good therapeutic target for brain injury

Researchers find high-resolution structure of immature Zika virus

Study offers new insights into mechanisms underlying action of motor proteins

TSRI researchers develop new approach to find how environmental estrogens impact public health

TSRI scientists develop new approach for understanding diverse effects of endocrine-disruptors

Study suggests new options for improving cancer immunotherapy

Acute stress can lead to delayed, long-term psychological trauma

Super-resolution fluorescence microscopy sheds light on brain’s molecular mechanism

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