Protein News and Research

RSS

Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Three missense variants of BRCA1 gene linked to breast or ovarian cancer risk, study shows

Researchers of the hereditary cancer research group at the Bellvitge Biomedical Research Institute and the Catalan Institute of Oncology conducted a functional and structural study of seven missense variants of the BRCA1 gene concluding that three of these variants are pathogenic, linked to the risk of suffering breast or ovarian cancer.

19 Apr 2013

Research: Gene behind epilepsy syndrome could play a key role in other idiopathic epilepsies

Researchers at the University Department of Neurology at the MedUni Vienna have identified a gene behind an epilepsy syndrome, which could also play an important role in other idiopathic (genetically caused) epilepsies.

18 Apr 2013

Running or jumping may worsen cartilage damage, MIT engineers find

Osteoarthritis, which affects at least 20 percent of adults in the United States, leads to deterioration of cartilage, the rubbery tissue that prevents bones from rubbing together.

18 Apr 2013

Study highlights importance of zebrafish as a model organism for human disease research

Researchers demonstrate today that 70 per cent of protein-coding human genes are related to genes found in the zebrafish and that 84 per cent of genes known to be associated with human disease have a zebrafish counterpart.

18 Apr 2013

ARMGO Pharma gets $1 million to support ARM210 preclinical work for DMD treatment

ARMGO Pharma and the Muscular Dystrophy Association today announced that $1 Million has been awarded for preclinical work in support of an Investigational New Drug application with the U.S. Food and Drug Administration for ARM210, a novel, orally available, small-molecule Rycal drug that has potential as a treatment for Duchenne muscular dystrophy.

18 Apr 2013

Two abstracts related to Advaxis' ADXS-HPV selected for poster presentation at ASCO meeting

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, announced that two abstracts related to ADXS-HPV (ADXS11-001), the Company's lead clinical stage product candidate, have been selected for poster presentation at the 2013 American Society of Clinical Oncology Annual Meeting in Chicago, IL, from May 31 - June 4, 2013, at the McCormick Place Convention Center.

18 Apr 2013

CRISPR helps some bacteria evade mammalian immune system

CRISPR, a system of genes that bacteria use to defend themselves against viruses, has been found to be involved in helping some bacteria evade the mammalian immune system.

18 Apr 2013

Preclinical studies show bladder cancers, mesotheliomas respond to treatment with ADI-PEG 20

Scientists from academic institutions reported at the 2013 annual American Association for Cancer Research meeting, results from preclinical studies which showed that certain bladder cancers and mesotheliomas have metabolic changes and are more likely to respond to treatment with ADI-PEG 20 (pegylated arginine deiminase) if they are deficient in the enzyme, argininosuccinate synthetase.

18 Apr 2013

NCI researchers overcome major impediment to development of effective stem cell therapies

Scientists have overcome a major impediment to the development of effective stem cell therapies by studying mice that lack CD47, a protein found on the surface of both healthy and cancer cells.

18 Apr 2013

Scientists reveal that stem cells, tissue-specific cells can be grown from mature mammalian cells

tem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the National Institutes of Health.

18 Apr 2013

UTHealth neuroscientists demonstrate new strategy to overcome memory deficits

Neuroscientists at The University of Texas Health Science Center at Houston have taken a major step in their efforts to help people with memory loss tied to brain disorders such as Alzheimer's disease.

18 Apr 2013

Findings hold promise for development of therapies to fight different viral infections

The human body has the ability to ward off viruses by activating a naturally occurring protein at the cellular level, setting off a chain reaction that disrupts the levels of cholesterol required in cell membranes to enable viruses to enter cells.

18 Apr 2013

UTMB researchers identify protein that can interfere with the brain's response to leptin

Ever since the appetite-regulation hormone called leptin was discovered in 1994, scientists have sought to understand the mechanisms that control its action. It was known that leptin was made by fat cells, reduced appetite and interacted with insulin , but the precise molecular details of its function -details that might enable the creation of a new treatment for obesity - remained elusive.

18 Apr 2013

New pre-clinical study suggests novel drug combination therapy for leukemia treatment

A new, pre-clinical study by researchers at Virginia Commonwealth University Massey Cancer Center suggests that a novel drug combination could lead to profound leukemia cell death by disrupting the function of two major pro-survival proteins.

18 Apr 2013

Examining function of all genes in zebrafish genome could benefit human health, researchers say

Equipped with the zebrafish genome, researchers have designed a method to assay the function of each and every gene and to explore the effects genetic variation has on zebrafish.

18 Apr 2013

Research findings could lead to novel approaches for eliminating reservoirs of HIV-1

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the protein that blocks HIV-1 from multiplying in white blood cells is regulated.

18 Apr 2013

New research reveals how acute stress primes brain for improved performance

Overworked and stressed out? Look on the bright side. Some stress is good for you. "You always think about stress as a really bad thing, but it's not," said Daniela Kaufer, associate professor of integrative biology at the University of California, Berkeley.

17 Apr 2013

Research: Transcription factors regulating oxygen levels in blood play a role in melanoma metastases

Researchers at the University of North Carolina have discovered that transcription factors regulating the levels of oxygen in the blood also play a role in the spread of the skin cancer melanoma.

17 Apr 2013

Study shows TOLLIP gene variant is linked to increased mortality risk in IPF patients

A new study looking at the genomes of more than 1,500 patients with idiopathic pulmonary fibrosis, a rare and devastating lung disease, found multiple genetic associations with the disease, including one gene variant that was linked to an increase in the risk of death.

17 Apr 2013

Santarus, Pharming Group submit Biologics License Application to FDA for RUCONEST

Santarus, Inc. and Pharming Group NV today announced the submission of a Biologics License Application to the U.S. Food and Drug Administration to obtain marketing approval for RUCONEST (recombinant human C1 esterase inhibitor) 50 U/kg, an investigational drug for the treatment of acute angioedema attacks in patients with hereditary angioedema.

17 Apr 2013

Protein News and Research

Further Reading

Three missense variants of BRCA1 gene linked to breast or ovarian cancer risk, study shows

Research: Gene behind epilepsy syndrome could play a key role in other idiopathic epilepsies

Running or jumping may worsen cartilage damage, MIT engineers find

Study highlights importance of zebrafish as a model organism for human disease research

ARMGO Pharma gets $1 million to support ARM210 preclinical work for DMD treatment

Two abstracts related to Advaxis' ADXS-HPV selected for poster presentation at ASCO meeting

CRISPR helps some bacteria evade mammalian immune system

Preclinical studies show bladder cancers, mesotheliomas respond to treatment with ADI-PEG 20

NCI researchers overcome major impediment to development of effective stem cell therapies

Scientists reveal that stem cells, tissue-specific cells can be grown from mature mammalian cells

UTHealth neuroscientists demonstrate new strategy to overcome memory deficits

Findings hold promise for development of therapies to fight different viral infections

UTMB researchers identify protein that can interfere with the brain's response to leptin

New pre-clinical study suggests novel drug combination therapy for leukemia treatment

Examining function of all genes in zebrafish genome could benefit human health, researchers say

Research findings could lead to novel approaches for eliminating reservoirs of HIV-1

New research reveals how acute stress primes brain for improved performance

Research: Transcription factors regulating oxygen levels in blood play a role in melanoma metastases

Study shows TOLLIP gene variant is linked to increased mortality risk in IPF patients

Santarus, Pharming Group submit Biologics License Application to FDA for RUCONEST

Industry Focus eBook - Protein Analysis (3rd edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics