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Implementation of large-scale genomic tumor profiling viable but faces several challenges

Researchers leading the largest genomic tumor profiling effort of its kind say such studies are technically feasible in a broad population of adult and pediatric patients with many different types of cancer, and that some patients can benefit by receiving precision drugs targeted to their tumors' mutations or being enrolled in clinical trials.

18 Nov 2016

Cigarette smoking may disrupt kidney-protective effects of medications in CKD patients

To improve care for patients with kidney dysfunction, investigators are striving to identify modifiable risk factors that may slow the progression of chronic kidney disease (CKD) to kidney failure.

17 Nov 2016

Study finds link between hypoglycemia and mortality risk in hospitalized patients

In hospitalized patients, low blood sugar—also known as hypoglycemia—is associated with increased short- and long-term mortality risk, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

17 Nov 2016

Study shows menopausal hormone therapy can improve bone mass and structure

Women who undergo hormone therapy for menopausal symptoms such as hot flashes can not only increase bone mass, but also can improve bone structure, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

17 Nov 2016

Dietary sodium restriction may provide kidney and heart benefits for CKD patients

New research indicates that reducing sodium intake may provide kidney and heart benefits for patients with chronic kidney disease (CKD).

17 Nov 2016

BAG3 protein plays protective role by limiting reperfusion injury to the heart

The inability of cells to eliminate damaged proteins and organelles following the blockage of a coronary artery and its subsequent re-opening with angioplasty or medications - a sequence known as ischemia/reperfusion - often results in irreparable damage to the heart muscle.

17 Nov 2016

Johns Hopkins researchers develop new, highly accurate urine test to predict risk for cervical cancer

Johns Hopkins Medicine specialists report they have developed a urine test for the likely emergence of cervical cancer that is highly accurate compared to other tests based on genetic markers derived directly from cervical tissue.

17 Nov 2016

Veterans Affairs researchers discover alleles of certain genes that offer protection from GWI

Veterans Affairs researchers have found that certain forms, or alleles, of a gene known to play a key role in the immune system appear to offer protection from Gulf War illness (GWI). Further, they discovered how such protection is manifested in the brain.

17 Nov 2016

Hepatitis C virus sabotages antiviral defenses of liver cells by blunting effect of immune proteins

The virus that causes hepatitis C protects itself by blocking signals that call up immune defenses in liver cells, according to University of Washington researchers and colleagues reporting Nov. 14 in Nature Medicine.

17 Nov 2016

Biochemists solve puzzle of putrid camel pee to unearth potential target for treating sleeping sickness

Biochemists from Trinity College Dublin have solved an old mystery as to the cause of especially smelly camel urine, with implications for the millions of people affected by African parasites called trypanosomes.

17 Nov 2016

Scientists reveal key details of the body's immune response to fungal infections

Every year, fungal infections threaten thousands of patients -- from those with depressed immune systems to others who have had surgeries or devices such as catheters implanted. Moreover, some anti-fungal medications are beginning to lose their power.

17 Nov 2016

T cell channel could be potential new target for treating head and neck cancers

Researchers at the University of Cincinnati have discovered that an ion channel, active within T cells (white blood cells), could be targeted to reduce the growth of head and neck cancers.

17 Nov 2016

Study finds positive link between later age at last pregnancy and cognitive function after menopause

A new study has found that women have better brainpower after menopause if they had their last baby after age 35, used hormonal contraceptives for more than 10 years or began their menstrual cycle before turning 13.

17 Nov 2016

New mouse model by FDA's scientists provides platform for improving understanding of Zika virus pathology

A new mouse model developed by scientists at the U.S. Food and Drug Administration may help in exploring the potential activity of Zika virus vaccines and therapeutics.

17 Nov 2016

Scientists examine new class of small molecules with potential to improve cryopreservation

Freezing and reanimating your body is still science fiction, but cryopreserving cells and certain tissues for future use is a reality.

17 Nov 2016

Researchers need to know more about proinsulin misfolding to better understand diabetes

According to the World Health Organization, 422 million adults across the globe have diabetes. In fact, the number of adults with the disease continues to grow each year.

17 Nov 2016

Researchers create temporal and spatial atlas that plots development of mouse heart

It's not simple, making a heart. In the womb, the organ begins as a tube, sprouts bead-like lumps, folds in on itself and eventually morphs into the more familiar-looking four-chambered structure.

17 Nov 2016

Researchers developing biomaterial with potential to treat vascular bleeding

Researchers at Mayo Clinic, Harvard Medical School and the Massachusetts Institute of Technology are developing a biomaterial that has potential to protect patients at high risk for bleeding in surgery.

17 Nov 2016

Global high blood pressure has almost doubled over past 40 years, shows study

In the past 40 years, there has been a large increase in the number of people living with high blood pressure worldwide because of population growth and ageing—rising from 594 million in 1975 to over 1.1 billion in 2015.

17 Nov 2016

Epigem challenges Durham University students to develop diagnostic devices for rare anaemic conditions

Epigem, a high-tech British micro engineering company, has issued a blood challenge to students from the Durham University-led SOFI CDT (Centre for Doctoral Training in Soft Matter and Functional Interfaces).

17 Nov 2016

Blood News and Research

Implementation of large-scale genomic tumor profiling viable but faces several challenges

Cigarette smoking may disrupt kidney-protective effects of medications in CKD patients

Study finds link between hypoglycemia and mortality risk in hospitalized patients

Study shows menopausal hormone therapy can improve bone mass and structure

Dietary sodium restriction may provide kidney and heart benefits for CKD patients

BAG3 protein plays protective role by limiting reperfusion injury to the heart

Johns Hopkins researchers develop new, highly accurate urine test to predict risk for cervical cancer

Veterans Affairs researchers discover alleles of certain genes that offer protection from GWI

Hepatitis C virus sabotages antiviral defenses of liver cells by blunting effect of immune proteins

Biochemists solve puzzle of putrid camel pee to unearth potential target for treating sleeping sickness

Scientists reveal key details of the body's immune response to fungal infections

T cell channel could be potential new target for treating head and neck cancers

Study finds positive link between later age at last pregnancy and cognitive function after menopause

New mouse model by FDA's scientists provides platform for improving understanding of Zika virus pathology

Scientists examine new class of small molecules with potential to improve cryopreservation

Researchers need to know more about proinsulin misfolding to better understand diabetes

Researchers create temporal and spatial atlas that plots development of mouse heart

Researchers developing biomaterial with potential to treat vascular bleeding

Global high blood pressure has almost doubled over past 40 years, shows study

Epigem challenges Durham University students to develop diagnostic devices for rare anaemic conditions

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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