Laboratory News and Research

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Morgan Stanley Children's Hospital performs transcatheter pulmonary valve replacement

A breakthrough new procedure may improve quality of life for children and adults with a common type of congenital heart defect that interferes with the body's ability to oxygenate blood through the lungs.

24 Aug 2007

Scientists investigate initial molecular mechanism that triggers neuronal firing

Carnegie Mellon University chemists have solved a decade-long molecular mystery that could eventually help scientists develop drug therapies to treat a variety of disorders, including epilepsy and Alzheimer's disease.

24 Aug 2007

Rapamycin study is first stage in development of new treatment

Rapamycin isn't your ordinary potential anti-cancer drug…It had a long and somewhat exotic history before undergoing preclinical (laboratory-based) studies at St. Jude as part of a national Pediatric Preclinical Testing Program (PPTP) investigation of its anticancer activity.

23 Aug 2007

Global public health security in the 21st century

More than at any previous time in history, global public health security depends on international cooperation and the willingness of all countries to act effectively in tackling new and emerging threats.

23 Aug 2007

Sewage reveals community-wide illegal drug use

Public health officials may soon be able to flush out more accurate estimates on illegal drug use in communities across the country thanks to screening test described at the 234 th national meeting of the American Chemical Society, the world's largest scientific society.

22 Aug 2007

Natural antimicrobial agents for food safety

Two items high on the list of public concerns are the need for greater food safety and a growing demand for natural or organic food products.

22 Aug 2007

Cranberries, chemo and ovarian cancer

Compounds in cranberries may help improve the effectiveness of platinum drugs that are used in chemotherapy to fight ovarian cancer, researchers have found in a laboratory study that will be reported at the 234 th national meeting of the American Chemical Society.

22 Aug 2007

What's making you fat? - the answer could be a virus!

According to researchers in the U.S. a common virus (adenovirus-36), that causes throat and eye infections may play a part in obesity.

21 Aug 2007

Red and blue fruits and veggies the best for fighting cancer

A new study by scientists in the U.S. has found that red and blue foods are the best when it comes to fighting cancer.

20 Aug 2007

Tumors use enzyme to recruit regulatory T-cells and suppress immune response

One way tumors fly under the radar of the immune system is by using IDO, an enzyme used by fetuses to help avoid rejection, to recruit powerful regulatory T cells that turn down the immune response, researchers say.

17 Aug 2007

Reactivating a critical gene lost in kidney cancer reduces tumor growth

Researchers at Mayo Clinic Jacksonville, have found that a key gene is often silenced in clear cell renal cell carcinoma, the most common type of kidney cancer, and when they restored that gene in human kidney cancer cells in culture and animal experiments, tumors stopped growing and many disappeared.

17 Aug 2007

Obesity and aversion to exercise could enhance the risk of pancreatic cancer

Obesity and aversion to exercise have become hallmarks of modern society and a new study suggests that a blood protein linked to these lifestyle factors may be an indicator for an increased risk of developing pancreatic cancer.

17 Aug 2007

Mice use specialized neurons to detect carbon dioxide in the air

For mice, carbon dioxide often means danger - too many animals breathing in too small a space or a hungry predator exhaling nearby.

17 Aug 2007

Scientists describe a new way of creating novel enzymes

The intricate interplay of proteins and other chemicals that underlies most biological activities requires the participation of enzymes, specialized molecules that accelerate chemical reactions between molecules.

17 Aug 2007

New method to detect infection in prosthetic joints

A team of Mayo Clinic researchers has discovered a new, more accurate diagnostic test to detect infection of prosthetic joints, potentially leading to better treatment options and patient outcomes.

17 Aug 2007

First biomarker discovered that predicts prostate cancer outcome

Mayo Clinic researchers have identified the first immune molecule that appears to play a role in prostate cancer development and in predicting cancer recurrence and progression after surgery.

17 Aug 2007

New findings on cholesterol metabolism

A team of researchers investigating cholesterol and lipid transport has performed experiments that cast serious doubt on the dominant hypothesis of how the body rids its cells of "bad" cholesterol (LDL) and increases "good" cholesterol (HDL).

17 Aug 2007

Fibrin may be new target for Alzheimer's drugs

Despite the rapid rise of Alzheimer's disease - the Alzheimer's Association predicts as many as 7.7 million cases by 2030 - there are no preventative treatments available, few in the pharmaceutical pipeline, and those drugs being developed all share the same two molecular targets.

15 Aug 2007

Authorities accused of a cover-up in British foot and mouth scare

The British government has been accused of a cover-up over the foot and mouth outbreak in a research site which houses the government-backed Institute for Animal Health.

14 Aug 2007