Laboratory News and Research

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Researchers engineer adult stem cells derived from human umbilical cord blood to produce insulin

The researchers announced their laboratory finding, which caps nearly four years of research, in the June 2007 issue of the medical journal Cell Proliferation, posted online this week.

28 May 2007

Study challenges conventional wisdom about cancer cells

A team of St. Jude investigators challenged conventional wisdom about the eye cancer retinoblastoma by using a mouse model that allowed them to study the tumors as they develop and grow.

27 May 2007

Hormone therapy and menopause study

When is the best time in a woman's reproductive history to start hormone therapy?

24 May 2007

Researchers find alteration in gene associated with uterine cancer

Researchers at the Translational Genomics Research Institute (TGen) today announced the discovery of previously unrecognized alterations in a gene called FGFR2 in a subset of endometrial cancers, the most common gynecologic cancer in the United States.

24 May 2007

Study of Aripiprazole in adolescents with schizophrenia

In a six-week study in adolescents (13-17 years old) with schizophrenia, the Otsuka Pharmaceutical Co., Ltd. and Bristol-Myers Squibb Company atypical antipsychotic aripiprazole demonstrated significant improvement compared to placebo on the primary efficacy endpoint, Positive and Negative Syndrome Scale (PANSS) Total Score.

24 May 2007

Stem cells may look malignant, not act it

Call it the cellular equivalent of big glasses, a funny nose and a fake mustache.

24 May 2007

New smart pill helps diagnose stomach problems

People with the chronic stomach condition known as gastroparesis, or slow stomach emptying, live in fear that eating will cause an episode of nausea, vomiting and abdominal pain.

24 May 2007

New technique effective in closing accidental colonoscopy wounds

To prevent colon cancer, the second leading cause of United States cancer deaths, the American Cancer Society recommends that after age 50 people undergo colonoscopies every ten years to detect signs of that disease , either actual tumors or precancerous polyps.

24 May 2007

Genetic data overturns long-held theory of limb development

Long before animals with limbs (tetrapods) came onto the scene about 365 million years ago, fish already possessed the genes associated with helping to grow hands and feet (autopods) report University of Chicago researchers in Nature.

24 May 2007

Concentrated radio waves proide new approach to treating precancerous esophagus condition

The use of concentrated radio waves appears to be a safe and effective way to "burn" away abnormal cell growth in the esophagus that can be a precursor of cancer.

24 May 2007

Gene therapy used to reverse heart failure in animals

Heart researchers at the Center for Translational Medicine at Jefferson Medical College have used gene therapy to reverse heart failure in animals.

24 May 2007

Immune antibodies penetrate neurons to clear Alzheimer's-linked amyloid

Researchers at Weill Cornell Medical College have gotten much closer to understanding how immune-based therapies can treat Alzheimer's disease -- by studying how antibodies go inside brain cells to reduce levels of Alzheimer's-linked amyloid peptides that form plaques between neurons.

24 May 2007

Visual short-term memory capacity drops following sleep deprivation

When an air traffic controller at the end of a double shift forgets the location of an aircraft that had recently appeared on his screen, it may be that he did not properly take in the visual information.

24 May 2007

Effects of estrogen therapy with perimenopausal women

When is the best time in a woman's reproductive history to start hormone therapy? How does estrogen therapy affect a woman's cognition and mood? What is the most beneficial form of estrogen?

24 May 2007

Breakthrough in understanding how cancers spread

The University of Manchester study used embryonic stem (ES) cells to investigate how some tumours are able to migrate to other parts of the body, which makes the treatment of cancer much more difficult.

From The University of Manchester 24 May 2007

Groundbreaking research on type 1 congenital myotonic dystrophy

Each year, the parents of an estimated one in 20,000 newborns are shocked to learn their child has type 1 congenital myotonic dystrophy (CDM1), a progressive and crippling genetic disorder.

24 May 2007

New understanding of how immune-based therapies can treat Alzheimer's disease

24 May 2007

Scientists evolve new proteins from scratch

Nature, through the trial and error of evolution, has discovered a vast diversity of life from what can only presumed to have been a primordial pool of building blocks.

24 May 2007

Targeted nanoparticles offer promising techniques for cancer treatment

Researchers in the laboratory of Mark E. Davis at the California Institute of Technology have been using small interfering RNA (siRNA), sometimes known as silencing RNA, to "silence" specific genes that are implicated in certain malignancies.

22 May 2007

Brca2 gene prevents medulloblastoma

Investigators at St. Jude Children's Research Hospital have gained some of the first major insights into how certain genes known to prevent cancer also guide the normal development of the nervous system before birth and during infancy by repairing DNA damage.

22 May 2007