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Patients with hypothyroidism have nagging symptoms despite normal TSH tests, medication use

About 15 percent of the 10-12 million people in the U.S. with hypothyroidism, or an underactive thyroid, continue to feel sick despite following the standard of care recommended by the American Thyroid Association.

13 Oct 2016

IPC PAS researchers develop new polymer that may detect early stages of kidney disease

The advanced phase of acute kidney injury can be fatal in even one in two patients. Fortunately, now it will be possible to detect the disease in its initial stages, when treatment is still relatively simple and the prognosis good.

13 Oct 2016

Minimally-invasive procedure to fix aortic aneurysm linked to increase in long-term complications

A minimally-invasive procedure to fix a life-threatening condition may be associated with an increase in long-term complications, compared to an alternative procedure.

13 Oct 2016

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of affected patients.

12 Oct 2016

Study to investigate clinical impact of new treatment for HFrEF patients

The academic partners in the VerICiguaT GlObal Study in Subjects with Heart Failure with Reduced EjectIon FrAction are pleased to announce that patient enrollment has begun.

12 Oct 2016

Study suggests possibility for small molecule drug/antibody combinatorial therapy to treat neuroblastoma

A study by a multidisciplinary team of researchers from The Saban Research Institute of Children's Hospital Los Angeles sheds further light on the role of the cytokine TGFβ1 in the growth of neuroblastoma, and suggests the possibility for a small molecule drug/antibody combinatorial therapy to treat this cancer.

12 Oct 2016

Research findings raise hope for better treatment of diabetic wounds

Diabetics often have to contend with wounds that heal poorly. Researchers at the Max Planck Institute for Biology of Ageing, the CECAD Excellence Cluster and the Institute of Genetics of the University of Cologne have now gained fresh insights into the underlying cellular mechanisms.

12 Oct 2016

Study identifies mechanistic link between maternal obesity and childhood hypertension

Exposure of babies to high levels of the 'fullness' hormone, leptin, in the womb irreversibly activates receptors in the brain that regulate blood pressure, according to a new study by researchers from King's College London, part-funded by the British Heart Foundation.

12 Oct 2016

Novel method can quantify progression of NAFLD to more advanced fibrosis and cirrhosis

Combining multiple non-invasive measures, researchers at University of California San Diego School of Medicine describe a novel method to quantify the progression of nonalcoholic fatty liver disease (NAFLD) to its more dangerous and deadly states — advanced fibrosis and cirrhosis.

12 Oct 2016

High-protein diet eliminates metabolic benefits of weight loss in obese women

Dieters sometimes consume extra protein to stave off hunger and prevent loss of muscle tissue that often comes with weight loss.

12 Oct 2016

Calcium supplements may raise risk of plaque buildup in arteries and heart damage

After analyzing 10 years of medical tests on more than 2,700 people in a federally funded heart disease study, researchers at Johns Hopkins Medicine and elsewhere conclude that taking calcium in the form of supplements may raise the risk of plaque buildup in arteries and heart damage, although a diet high in calcium-rich foods appears be protective.

12 Oct 2016

New T cell subset may play vital role in development of type 1 diabetes

A study conducted at the University of Eastern Finland revealed that a recently described T cell subset may have a central role in the development of type 1 diabetes.

12 Oct 2016

Novel biomarkers enhance power to predict therapeutic efficacy in LN prognostic models

Results of preclinical studies by investigators at the Medical University of South Carolina reported in the August 2016 issue of Arthritis & Rheumatology demonstrate for the first time that including novel biomarkers in lupus nephritis (LN) prognostic models significantly increases their power to predict therapeutic efficacy.

12 Oct 2016

Scientists use 3-D printing to develop customized biodegradable stents

Most people have heard about personalized medicine. But how about personalized medical devices? Northwestern Engineering's Guillermo Ameer and Cheng Sun have teamed up to use 3-D printing to develop flexible, biodegradable stents that are customized for a specific patient's body.

12 Oct 2016

An inclusive approach to COPD research: an interview with Dr David Leather

About eight years ago the WHO put out a call saying that we needed data that better represented real world patients. Our ambition was to create evidence earlier in the life cycle of medicine that better represented the population that would...

11 Oct 2016

Fighting malaria by altering human flavor

A new study by Johns Hopkins researchers suggests that a specialized area of the mosquito brain mixes tastes with smells to create unique and preferred flavors. The findings advance the possibility, they say, of identifying a substance that makes “human flavor” repulsive to the malaria-bearing species of the mosquitoes, so instead of feasting on us, they keep the disease to themselves, potentially saving an estimated 450,000 lives a year worldwide.

11 Oct 2016

Brain atrophy patterns linked to loss of specific cognitive abilities in patients with Alzheimer's disease

Mathematical modeling of the brain scans of patients with Alzheimer's disease and others at risk for the devastating neurodegenerative disorder has identified specific patterns of brain atrophy that appear to be related to the loss of particular cognitive abilities.

8 Oct 2016

Study of pan-FGFR inhibitor uses mRNA in tumours to identify responders

The first-in-human dose escalation study of the pan-FGFR (fibroblast growth factor receptor) inhibitor BAY 1163877 in patients with treatment-refractory locally advanced or metastatic solid tumours were reported today at the ESMO 2016 Congress in Copenhagen.

8 Oct 2016

Children of mothers with high levels of vitamin D in umbilical blood have fewer symptoms of ADHD

Children of mothers who took vitamin D during pregnancy with resultant high levels of the vitamin in the umbilical blood have fewer symptoms of ADHD at the age of 2½ years.

7 Oct 2016

Study reveals mechanism that regulates fluid intake in the body to prevent fatal water intoxication

A multi-institute study led by Monash University has revealed for the first time the mechanism that regulates fluid intake in the human body and stops us from over-drinking, which can cause potentially fatal water intoxication.

7 Oct 2016

Blood News and Research

Patients with hypothyroidism have nagging symptoms despite normal TSH tests, medication use

IPC PAS researchers develop new polymer that may detect early stages of kidney disease

Minimally-invasive procedure to fix aortic aneurysm linked to increase in long-term complications

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

Study to investigate clinical impact of new treatment for HFrEF patients

Study suggests possibility for small molecule drug/antibody combinatorial therapy to treat neuroblastoma

Research findings raise hope for better treatment of diabetic wounds

Study identifies mechanistic link between maternal obesity and childhood hypertension

Novel method can quantify progression of NAFLD to more advanced fibrosis and cirrhosis

High-protein diet eliminates metabolic benefits of weight loss in obese women

Calcium supplements may raise risk of plaque buildup in arteries and heart damage

New T cell subset may play vital role in development of type 1 diabetes

Novel biomarkers enhance power to predict therapeutic efficacy in LN prognostic models

Scientists use 3-D printing to develop customized biodegradable stents

An inclusive approach to COPD research: an interview with Dr David Leather

Fighting malaria by altering human flavor

Brain atrophy patterns linked to loss of specific cognitive abilities in patients with Alzheimer's disease

Study of pan-FGFR inhibitor uses mRNA in tumours to identify responders

Children of mothers with high levels of vitamin D in umbilical blood have fewer symptoms of ADHD

Study reveals mechanism that regulates fluid intake in the body to prevent fatal water intoxication

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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