Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Study: Patients operated by higher volume mitral surgeons experience lower mortality and reoperations

Surgeons who perform more than 25 mitral valve operations a year are more likely to perform repairs that are durable, and their patients are more likely to be alive a year after the operation, than when operations are performed by lower-volume surgeons, an Icahn School of Medicine at Mount Sinai study has found.

3 May 2017

Infantile spasms and multiple sclerosis relapse data presented at AAN

Mallinckrodt plc, a specialty pharmaceutical company, announced new results from two company-sponsored studies: one study on use of H.P. Acthar® Gel (repository corticotropin injection) in patients with infantile spasms (IS) and a second study on the economic burden of moderate-to-severe multiple sclerosis (MS) relapse.

2 May 2017

Knocking out lipid-modifying enzyme can boost post-heart attack healing, study shows

Two immune responses are important for recovery after a heart attack - an acute inflammatory response that attracts leukocyte immune cells to remove dead tissue, followed by a resolving response that allows healing.

2 May 2017

Scientists aim to offer better treatment for acute heart failure using ultrasound evaluation

A new clinical study of the German Centre for Cardiovascular Research is examining whether an ultrasound evaluation of the inferior vena cava in acute decompensated heart failure with congestion can be implemented in hospitals' everyday routine and also be conducted in a sufficiently large number of patients.

28 Apr 2017

Researchers to create new information technology for helping older adults with heart failure

A team of researchers is creating new information technology to help older adults with chronic heart failure. For the first time, researchers are capturing and working to empower individuals with their own heart health data.

27 Apr 2017

Hospitals may be unfairly penalized for readmission of heart attack patients, study suggests

A program that penalizes hospitals for high early readmission rates of heart attack patients may be unfairly penalizing hospitals that serve a large proportion of African-Americans and those with more severe illness, a study by UT Southwestern Medical Center researchers suggests.

26 Apr 2017

Whole-exome sequencing may routinely miss detecting some disease-causing genes, say researchers

Whole-exome DNA sequencing -- a technology that saves time and money by sequencing only protein-coding regions and not the entire genome -- may routinely miss detecting some genetic variations associated with disease, according to Penn State researchers who have developed new ways to identify such omissions.

24 Apr 2017

Scientists receive $2.8 million federal grant for diabetic cardiomyopathy research

Researchers from Georgia State University's Center for Molecular & Translational Medicine have received a four-year, $2.8 million federal grant to study diabetic cardiomyopathy, diabetes-related changes in the structure and function of the heart muscle.

24 Apr 2017

New article finds rising trend in hospitalization for hypertensive emergency with reduction in mortality

A new article published in the American Journal of Hypertension finds a rising trend in hospitalization for hypertensive emergency with reduction in hospital mortality during the last decade. The presence of acute cardiorespiratory failure, chest pain, stroke, acute chest pain, and aortic dissection were most predictive of higher hospital mortality among other complications.

21 Apr 2017

Drinking beetroot juice before working out makes aging brain look younger

Drinking a beetroot juice supplement before working out makes the brain of older adults perform more efficiently, mirroring the operations of a younger brain, according to a new study by scientists at Wake Forest University.

19 Apr 2017

AATS guidelines offer clear recommendations for treating ischemic mitral regurgitation

Mitral regurgitation can occur in up to 50% of patients with ischemic heart disease and even mild ischemic mitral regurgitation (IMR) has been linked to increased long-term mortality.

18 Apr 2017

Reduced kidney function is major contributor of cardiovascular deaths

A new analysis indicates that by 2013, cardiovascular deaths attributed to reduced kidney function outnumbered kidney failure deaths throughout the world.

17 Apr 2017

Chagas disease confirmed as 'silent killer' in first large-scale US survey

A study of almost 5,000 Latin American-born residents of Los Angeles County found that 1.24% tested positive for Chagas disease, a parasitic infection that can cause life-threatening heart damage if not treated early. Chagas disease is one of the leading causes of heart failure in Latin America.

14 Apr 2017

‘Vertical integration’ of healthcare leads to fewer hospital readmissions

"Vertical integration" of healthcare - closer coordination of care between primary care and hospitals - leads to a lower rate of hospital readmissions, suggests an experience from Portugal reported in the May issue of Medical Care. The journal is published by Wolters Kluwer.

13 Apr 2017

Researchers correct Duchenne muscular dystrophy using gene-editing alternative

Using the new gene-editing enzyme CRISPR-Cpf1, researchers at UT Southwestern Medical Center have successfully corrected Duchenne muscular dystrophy in human cells and mice in the lab.

13 Apr 2017

Investigational device aims to minimize risk of cerebral damage during TAVR

One of the most common, and most serious, heart valve diseases is aortic stenosis. Left untreated, aortic stenosis gradually diminishes quality of life and leads to heart failure and death.

12 Apr 2017

VUMC reaches major milestone by completing 1,000 heart transplantations

Surgeons at Vanderbilt University Medical Center performed five heart transplants in four days to place the institution among an elite group of transplant centers in the country - reaching 1,000 heart transplantations.

7 Apr 2017

Greater body surface area linked to increased risk of atrial fibrillation in women

Big women have a nearly threefold greater risk of atrial fibrillation than small women, according to research presented today at EuroPrevent 2017. The study included 1.5 million women who were followed-up for more than 30 years.

7 Apr 2017

Study compares burden of adverse events in patients implanted with HeartMate 3 and Heartmate II

A six-month analysis of the pivotal MOMENTUM 3 trial found that patients implanted with the new HeartMate 3 left ventricular assist system (LVAS) had fewer adverse clotting and bleeding events than patients implanted with the control, HeartMate II LVAS.

7 Apr 2017

Tumor necrosis factor may help control blood pressure, study suggests

Investigators at the Ted Rogers Centre for Heart Research have discovered a surprising new role for tumor necrosis factor (TNF): namely, that it is a major regulator of small blood vessel function, the key determinant of blood pressure. The study is published online today in Nature Communications.

6 Apr 2017

Heart Failure News and Research

Further Reading

Study: Patients operated by higher volume mitral surgeons experience lower mortality and reoperations

Infantile spasms and multiple sclerosis relapse data presented at AAN

Knocking out lipid-modifying enzyme can boost post-heart attack healing, study shows

Scientists aim to offer better treatment for acute heart failure using ultrasound evaluation

Researchers to create new information technology for helping older adults with heart failure

Hospitals may be unfairly penalized for readmission of heart attack patients, study suggests

Whole-exome sequencing may routinely miss detecting some disease-causing genes, say researchers

Scientists receive $2.8 million federal grant for diabetic cardiomyopathy research

New article finds rising trend in hospitalization for hypertensive emergency with reduction in mortality

Drinking beetroot juice before working out makes aging brain look younger

AATS guidelines offer clear recommendations for treating ischemic mitral regurgitation

Reduced kidney function is major contributor of cardiovascular deaths

Chagas disease confirmed as 'silent killer' in first large-scale US survey

‘Vertical integration’ of healthcare leads to fewer hospital readmissions

Researchers correct Duchenne muscular dystrophy using gene-editing alternative

Investigational device aims to minimize risk of cerebral damage during TAVR

VUMC reaches major milestone by completing 1,000 heart transplantations

Greater body surface area linked to increased risk of atrial fibrillation in women

Study compares burden of adverse events in patients implanted with HeartMate 3 and Heartmate II

Tumor necrosis factor may help control blood pressure, study suggests

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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