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Researcher receives NIH grant to detect increasing Mtb activity in people with HIV

Tuberculosis (TB) is the leading cause of death worldwide among people infected with HIV.

29 Aug 2016

New research may explain why people with blood group O get more severely ill from cholera

People with blood type O often get more severely ill from cholera than people of other blood types. New research from Washington University School of Medicine in St. Louis may explain why.

29 Aug 2016

Fluid-filled sacs that brain cells make to trap amyloid may contribute to Alzheimer's disease

Vesicles, fluid-filled sacs that brain cells make to trap amyloid, a hallmark of Alzheimer's, appear to also contribute to the disease, scientists report.

29 Aug 2016

$Lipoprotein apheresis may have new role in patients with refractory angina$

Lipoprotein apheresis may have new role in patients with refractory angina

Initial investigation of patients with suspected coronary heart disease (CHD) using functional imaging - rather than guideline-directed care - resulted in significantly less unnecessary angiography, according to results of the CE-MARC 2 trial.

29 Aug 2016

Invasive imaging technique can help achieve better outcomes in patients undergoing PCI

An invasive imaging technique called optical coherence tomography (OCT) can visualize the coronary arteries in patients undergoing percutaneous coronary intervention (PCI) and lead to better outcomes compared to standard angiography-guided PCI, according to new findings reported here.

29 Aug 2016

Long-term exposure to combination of lower LDL-C and SBP can reduce cardiovascular risk

Long-term exposure to the combination of even modestly lower LDL cholesterol (LDL-C) and systolic blood pressure (SBP) has the potential to "dramatically reduce" a person's lifetime risk of cardiovascular disease, according to new findings reported at ESC Congress 2016.

29 Aug 2016

PCSK9 inhibitor can reduce need for apheresis treatment in patients with familial hypercholesterolemia

Patients who have heterozygous familial hypercholesterolemia (HeFH), a condition that causes abnormally raised low-density lipoprotein cholesterol (LDL-C) levels and premature cardiovascular disease, can significantly reduce or even eliminate their need for expensive and time-consuming apheresis treatments with the PCSK9 inhibitor alirocumab.

29 Aug 2016

Janssen seeks to extend DARZALEX license to benefit more multiple myeloma patients

Janssen-Cilag International NV has announced the submission of a Type II variation application to the European Medicines Agency (EMA), seeking to broaden the existing marketing authorisation for the immunotherapy DARZALEX® (daratumumab) to include treatment of adult patients with relapsed multiple myeloma who have received at least one prior therapy. The expanded indication is based on daratumumab in combination with lenalidomide (an immmunomodulatory agent) and dexamethasone, or bortezomib (a PI) and dexamethasone.

29 Aug 2016

Boehringer Ingelheim and Duke expand collaboration to create largest patient registry for idiopathic pulmonary fibrosis (IPF)

Boehringer Ingelheim Pharmaceuticals, Inc. and the Duke Clinical Research Institute (DCRI) announced today the expansion of the Idiopathic Pulmonary Fibrosis – PROspective Outcomes (IPF-PRO) Registry, a patient registry developed to uncover insights into IPF, a rare and serious lung disease. The expansion will increase the study enrollment from 300 patients at 18 study sites to 1,500 patients at approximately 45 sites, creating the largest registry of newly diagnosed IPF patients.

29 Aug 2016

Moderate physical activity reduces risk of acute cardiovascular event in older people

Moderate physical activity is associated with a greater than 50% reduction in cardiovascular death in over-65s, according to research presented at ESC Congress 2016 today. The 12 year study in nearly 2500 adults aged 65 to 74 years found that moderate physical activity reduced the risk of an acute cardiovascular event by more than 30%. High levels of physical activity led to greater risk reductions.

27 Aug 2016

Study: Low socioeconomic status linked to higher risk of second heart attack or stroke

Low socioeconomic status is associated with a higher risk of a second heart attack or stroke, according to research presented at ESC Congress 2016 today. The study in nearly 30 000 patients with a prior heart attack found that the risk of a second event was 36% lower for those in the highest income quintile compared to the lowest and increased by 14% in divorced compared to married patients.

27 Aug 2016

Revised FDA guidance recommends universal testing of entire blood supply for Zika virus in the U.S.

As a further safety measure against the emerging Zika virus outbreak, today the U.S. Food and Drug Administration issued a revised guidance recommending universal testing of donated Whole Blood and blood components for Zika virus in the U.S. and its territories.

27 Aug 2016

Penn State dermatologist clarifies common myths about psoriasis

Psoriasis is a much-misunderstood disease, often kept under wraps by sufferers who want to hide their skin lesions.

26 Aug 2016

Study suggests microRNAs may connect inflammation with heart disease risk in obese people

Inflammation likely plays a role in the increased risk of heart disease that comes with obesity, but scientists don't fully understand how obesity leads to heart disease.

26 Aug 2016

Researchers explore molecular mechanisms through which lead exposure may affect neural stem cells

Researchers have identified a potential molecular mechanism through which lead, a pervasive environmental toxin, may harm neural stem cells and neurodevelopment in children.

26 Aug 2016

Anesthetic administered with nasal spray effective in preventing pain during dental treatment

A fear of pain causes many people with dental phobias to avoid or delay needed treatment. In some cases, the injection of a numbing agent can be the most painful part of the visit.

26 Aug 2016

Researchers find new way for early prediction of leukemic relapse

Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a particularly problematic disease that typically afflicts older patients who have often already experienced a bout with cancer.

26 Aug 2016

Paleo diet may be beneficial for heart health

The popular Paleo diet is based on eating foods thought to be available to our ancestors during the Paleolithic era, before the advent of dairy or processed grains.

26 Aug 2016

New drug delivery system slows and controls tumors not aiming for complete elimination

Researchers have created a new drug delivery system that could improve the effectiveness of an emerging concept in cancer treatment - to dramatically slow and control tumors on a long-term, sustained basis, not necessarily aiming for their complete elimination.

26 Aug 2016

IRB Barcelona review article provides insights into emerging field of shuttle peptides

IRB Barcelona researchers publish a review article on the emerging field of drug transporters that have the capacity to reach the brain more efficiently.

26 Aug 2016

Blood News and Research

Researcher receives NIH grant to detect increasing Mtb activity in people with HIV

New research may explain why people with blood group O get more severely ill from cholera

Fluid-filled sacs that brain cells make to trap amyloid may contribute to Alzheimer's disease

Lipoprotein apheresis may have new role in patients with refractory angina

Invasive imaging technique can help achieve better outcomes in patients undergoing PCI

Long-term exposure to combination of lower LDL-C and SBP can reduce cardiovascular risk

PCSK9 inhibitor can reduce need for apheresis treatment in patients with familial hypercholesterolemia

Janssen seeks to extend DARZALEX license to benefit more multiple myeloma patients

Boehringer Ingelheim and Duke expand collaboration to create largest patient registry for idiopathic pulmonary fibrosis (IPF)

Moderate physical activity reduces risk of acute cardiovascular event in older people

Study: Low socioeconomic status linked to higher risk of second heart attack or stroke

Revised FDA guidance recommends universal testing of entire blood supply for Zika virus in the U.S.

Penn State dermatologist clarifies common myths about psoriasis

Study suggests microRNAs may connect inflammation with heart disease risk in obese people

Researchers explore molecular mechanisms through which lead exposure may affect neural stem cells

Anesthetic administered with nasal spray effective in preventing pain during dental treatment

Researchers find new way for early prediction of leukemic relapse

Paleo diet may be beneficial for heart health

New drug delivery system slows and controls tumors not aiming for complete elimination

IRB Barcelona review article provides insights into emerging field of shuttle peptides

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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