Amputations News and Research

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Avinger and PDL BioPharma close structured financing and royalty transaction

Avinger, Inc. and PDL BioPharma, Inc. (PDL) (NASDAQ: PDLI) announced today the closing of a structured financing and royalty transaction on April 18, 2013, in which PDL will provide Avinger with up to $40 million of mezzanine financing.

22 Apr 2013

KineMed renews research collaboration with Pfizer for advancement of novel diabetes pathways

KineMed Inc. today announced the renewal of a non-exclusive research collaboration with Pfizer Inc. for the advancement of novel approaches towards metabolic disease, in particular Type II Diabetes.

From Pfizer, Inc. 28 Mar 2013

MiR-198 controls migration of skin cells necessary for wounds to close and heal

Patients with diseases such as diabetes suffer from painful wounds that take a long time to heal making them more susceptible to infections that could even lead to amputations. A*STAR's discovery paves the way for therapeutics to improve healing of such chronic wounds, which are a significant burden to patients.

11 Mar 2013

New technology for rehabilitation of amputees

For the first time an operation has been conducted, at Sahlgrenska University Hospital, where electrodes have been permanently implanted in nerves and muscles of an amputee to directly control an arm prosthesis. The result allows natural control of an advanced robotic prosthesis, similarly to the motions of a natural limb.

25 Feb 2013

NeuroMetrix fourth quarter total revenues decrease to $1.5 million

NeuroMetrix, Inc., a medical device company focused on the diagnosis and treatment of the neurological complications of diabetes, today reported business and financial highlights for the quarter and twelve months ended December 31, 2012.

19 Feb 2013

Simple interventions can reduce amputations in diabetic patients by more than 50%

Every 30 seconds somebody in the world is amputated as a consequence of foot complication due to diabetes. A new study at Sahlgrenska Academy, University of Gothenburg, Sweden, confirmes that shoe inserts, podiatry, regular checkups and other simple interventions can reduce the number of amputations by more than 50%.

18 Jan 2013

Primary opponensplasty superior to osteosynthesis

Primary opponensplasty in toe transfers provides active restoration of thumb opposition and significantly better restoration of tripod pinch than does static opposition with osteosynthesis , research suggests.

20 Dec 2012

Gene therapy could represent new treatment option for severe orthopaedic injuries

Gene therapy involving modified stem cells obtained from fatty tissue and bone marrow could represent a new option for the treatment of severe orthopaedic injuries to the extremities.

7 Dec 2012

Loyola honors 45 extraordinary rehabilitation patients

Forty-five extraordinary rehabilitation patients were honored during Loyola University Medical Center's 2012 Annual Rehabilitation Patient of the Year celebration.

1 Dec 2012

Arginine and proline supplementation favor wound healing in diabetic rats

Chronic wounds such as foot ulcers are a common problem for diabetics and are the cause of more than 80 percent of the lower leg amputations in these patients. There is currently no effective way to improve healing of these types of wounds, but new research offers hope.

16 Nov 2012

ACOEM provides tools and resources to help employers manage diabetes

In recognition of November as National Diabetes Month, the American College of Occupational and Environmental Medicine (ACOEM) is providing tools and resources to help employers identify and respond to the impact of diabetes on worker health and productivity.

16 Nov 2012

Avinger receives FDA clearance for Ocelot System

Avinger, Inc., a medical device manufacturer of innovative, multi-functional catheters for crossing chronic total occlusions (CTOs) in patients with Peripheral Artery Disease (PAD), announces its Ocelot System has been cleared for sale in the U.S. by the Food and Drug Administration (FDA).

9 Nov 2012

New index can help clinicians assess patients' prosthetic arm progress

Amputees with a new prosthetic arm must learn how to use their device to perform everyday tasks that were once second nature. Taking off a shirt becomes a conscious, multistep effort: grasp the shirt, lift the shirt over the head, pull arms through the sleeves, place the shirt on the table, let go of the shirt.

1 Nov 2012

Geographic variations in US diabetic foot expenditure identified

Researchers report that in the USA, Medicare spending on patients with diabetic foot disease varies significantly between different hospital referral regions.

25 Oct 2012

Empire BlueCross BlueShield introduces Medicare Advantage plans in New York City

Empire BlueCross BlueShield is introducing a number of Medicare Advantage (MA) plans in New York City that include access to the acclaimed CareMore health delivery system, which helps members maintain their health.

15 Oct 2012

Study assesses ethnic disparities among construction workers with injuries

White non-Hispanic construction workers are awarded higher workers' compensation settlements in Illinois than Hispanic or black construction workers with similar injuries and disabilities, according to researchers at the University of Illinois at Chicago School of Public Health.

15 Oct 2012

Type 2 diabetes screening: an interview with Dr Simon Griffin, MRC Epidemiology Unit at Addenbrooke’s Hospital, Cambridge

Type 2 diabetes is a condition in which the body does not make sufficient insulin or the insulin it makes doesn’t work sufficiently well to maintain a normal level of blood glucose and so the blood glucose rises.

12 Oct 2012

Safety tips to avoid common farm injuries

The hectic fall harvest is under way, and that means the dangers of everyday farm work -- one of the nation's most hazardous occupations -- are compounded by the rush to bring in crops on time. Many agricultural injuries can be prevented with basic safety equipment and mindfulness about the need for caution on the job, says emergency medicine physician Howard Schumaker, M.D., of the Mayo Clinic Health System in Sparta.

11 Oct 2012

S100A1 protein critical for endothelial cell function in ischemic angiogenesis

Restoring diminished levels of a protein shown to prevent and reverse heart failure damage could also have therapeutic applications for patients with critical limb ischemia (CLI), suggests a new preclinical study published online October 9 in Circulation Research from researchers at the Center for Translational Medicine at Thomas Jefferson University.

11 Oct 2012

GW to evaluate effectiveness of glucose-lowering drugs against type 2 diabetes

John Lachin, professor of biostatistics, epidemiology and statistics at the George Washington University, has been awarded a five-year, $134 million grant from the National Institute of Health's National Institute of Diabetes and Digestive and Kidney Diseases to conduct a clinical trial examining the long-term effectiveness of several glucose-lowering medications for treatment of people with type 2 diabetes. The grant sets a record as the largest sum award GW has ever received.

27 Sep 2012