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Study to test ability of doxycycline dose to reduce growth of abdominal aortic aneurysms

A new clinical study at the University of Michigan Health System will test the ability of a once daily dose of doxycycline to reduce the growth of small abdominal aortic aneurysms.

29 Aug 2013

Study shows continuous CSF drainage is associated with complications in patients with SAH

Researchers at Duke University conducted a randomized clinical trial in patients with subarachnoid hemorrhage (SAH). In this study, the researchers compared two approaches to intracranial pressure management-continuous and intermittent drainage of cerebrospinal fluid (CSF)-and outcomes associated with those methods, focusing specifically on the incidence of cerebral vasospasm.

21 Aug 2013

Researchers find recurrent genetic mutation linked to deadly thoracic aortic dissections

A multi-institutional team led by Dianna Milewicz, M.D., Ph.D., of The University of Texas Health Science Center at Houston (UTHealth) has found a recurrent genetic mutation that has been linked to deadly thoracic aortic dissections in family members as young as 17 years of age.

16 Aug 2013

Personalized models for preventive health care services

With physicians facing increasing demands on their time, it can be extremely difficult to prioritize which preventive care methods should be used for their patients. Now, two researchers at NYU Langone Medical Center have developed a mathematical model that will save time, lead to enhanced care, and potentially save lives.

6 Aug 2013

Faulty genetic pathway is a potent player in many types of allergies, say researchers

Newly published research by investigators at the Johns Hopkins Children's Center and the Johns Hopkins Institute of Genetic Medicine reveals that a faulty genetic pathway already known for its role in some connective tissue disorders is also a potent player in many types of allergies.

25 Jul 2013

Family and friends' fears of recurrence impact on patient's recovery after SAH

Researchers from Durham University and Kings College London (United Kingdom) and the University of Erlangen-N-rnberg (Germany) found that patients who have suffered a subarachnoid hemorrhage (SAH) may not recover psychosocially as well as expected if their significant other is excessively fearful about the possibility of SAH recurrence.

24 Jul 2013

ACS NSQIP hospitals have consistently better surgical outcomes, new study finds

A new study evaluating surgical outcomes at California hospitals enrolled in the American College of Surgeons National Surgical Quality Improvement Program found surgical patients at ACS NSQIP hospitals had significantly reduced mortality rates compared with non-ACS NSQIP hospitals.

16 Jul 2013

Weekend reading: Doctors who decide, death desires, and decisions

On the last week of April earlier this year, a small committee of doctors met quietly in a midsized ballroom at the Renaissance Hotel in Chicago. There was an anesthesiologist, an ophthalmologist, a radiologist, and so on - thirty-one in all, each representing their own medical specialty society, each a heavy hitter in his or her own field.

12 Jul 2013

Growing brain aneurysms 12 times more likely to burst, says new UCLA study

Brain aneurysms of all sizes—even small ones no larger than a pea—are up to 12 times more likely to rupture if they are growing, according to a new UCLA study.

3 Jul 2013

Cerebral aneurysms are more likely to rupture if they grow in size

Cerebral aneurysms of all sizes-even small ones below seven millimeters-are 12 times more likely to rupture if they are growing in size, according to a new study published online in the journal Radiology.

2 Jul 2013

Edge Therapeutics announces positive preliminary results from EG-1962 study for prevention of DCI

Edge Therapeutics announced today positive preliminary results from the first human use of EG-1962, the Company's novel bioabsorbable nimodipine microparticle formulation for the prevention of delayed cerebral ischemia, a life-threatening complication of subarachnoid hemorrhage, typically resulting from a ruptured brain aneurysm or traumatic brain injury.

27 Jun 2013

Smoking before surgery can lead to morbidity and complications for neurosurgical procedures

The effects of long-term cigarette smoking on morbidity and mortality have long been known. In a more immediate sense, smoking in the days and weeks before surgery can lead to morbidity and complications for many surgical procedures.

19 Jun 2013

Final results of PUFs clinical study of Covidien's Pipeline device published in June issue of Radiology

Covidien, a leading global provider of healthcare products, today announced that the final results of the PUFs (Pipeline for Uncoilable or Failed Aneurysms) clinical study of its Pipeline embolization device have been published in the June issue of Radiology.

17 Jun 2013

Next-generation self-expanding clot removal device from Codman Neuro obtains CE mark

Codman Neuro*, part of DePuy Synthes Companies of Johnson & Johnson, has obtained CE marking for REVIVE SE, a next-generation self-expanding clot removal device for use in treating acute ischemic stroke, the company announced today at the Live Interventional Neuroradiology & Neurosurgery Course (LINNC) in Paris.

13 Jun 2013

Report shows low baseline DBP associated with brain atrophy in patients with arterial disease

Low baseline diastolic blood pressure appears to be associated with brain atrophy in patients with arterial disease, whenever declining levels of blood pressure over time among patients who had a higher baseline BP were associated with less progression of atrophy, according to a report published Online First by JAMA Neurology, a JAMA Network publication.

11 Jun 2013

Edge Therapeutics announces FDA acceptance of IND application for EG-1962

Edge Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products for acute, fatal or debilitating conditions, announced today that the U.S. Food and Drug Administration has accepted the Company's Investigational New Drug application for EG-1962, a novel bio-absorbable nimodipine microparticle formulation.

10 Jun 2013

Mayo Clinic research shows that revascularization has reduced need for amputations by 40%

Peripheral arterial disease is a common circulation problem in which reduced blood flow can lead to complications that jeopardize the limbs, possibly even requiring amputation. Procedures known as revascularization have reduced the need for amputations 40 percent over two decades, Mayo Clinic research shows.

1 Jun 2013

Ongoing clinical study to evaluate benefits of high-dose simvastatin for patients with SAH

Can treatment with high doses of a cholesterol-lowering statin drug improve outcomes for patients with stroke caused by rupture and bleeding of brain aneurysms? An ongoing clinical trial will soon find out, according to an article in the May issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

22 May 2013

New study identifies risk factors for rupture or bleeding in children with arachnoid cysts

Arachnoid cysts are a common type of brain lesion that is usually harmless, but with a risk of rupture or bleeding. A new study identifies risk factors for rupture or bleeding in children with "incidentally" detected arachnoid cysts, reports the May issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.