Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Alzheimer’s blood biomarkers predict faster muscle strength loss in older adults

A large Swedish cohort study found that elevated blood biomarkers associated with Alzheimer’s disease—including p-tau217, p-tau181, neurofilament light chain, and GFAP—predict accelerated muscle strength decline over 12 years in dementia-free older adults. These findings suggest that early identification of Alzheimer’s-related biomarkers could help clinicians intervene sooner to prevent sarcopenia and related adverse outcomes in aging populations.

27 May 2025

Blood test pinpoints early Alzheimer’s risk with high accuracy

Researchers evaluated a fully automated plasma biomarker panel to detect early amyloid-β accumulation in cognitively unimpaired adults at risk for Alzheimer’s disease. Plasma p-tau217/Aβ42 emerged as the most robust and accurate blood-based marker for identifying preclinical amyloid pathology.

26 May 2025

Study uncovers new molecular mechanisms linked to Alzheimer's cognitive decline

A research team at the University of Barcelona's Institute of Neurosciences (UBneuro) has discovered new molecular mechanisms related to the cognitive decline associated with Alzheimer's disease, the most common dementia.

26 May 2025

Autophagy-based mechanism provides insight into Parkinson’s disease protein secretion

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells.

23 May 2025

Unlocking the secrets of human longevity and healthy aging

Human healthy aging and longevity are complex phenomena influenced by a dynamic interplay of genetic, epigenetic, metabolic, immune, and environmental factors.

22 May 2025

Insulin resistance in the brain may link Alzheimer’s and epilepsy

Researchers at the University of São Paulo (USP) in Brazil have succeeded in showing, in an animal model, that the process of insulin resistance in the brain affects both Alzheimer's disease and epilepsy and may be a linking factor between the two diseases.

22 May 2025

How innovation in dried blood spot testing is transforming neurological disease monitoring

In this interview, NewsMedical speaks with Quanterix about blood spot testing for neurological applications.

From Quanterix 21 May 2025

Exploring the link between microbial balance and aging mechanisms

Aging is a multifaceted process driven by interconnected biological mechanisms, among which genomic instability and telomere attrition stand as primary hallmarks.

20 May 2025

MIT researchers discover new potential drug targets for Alzheimer’s disease

By combining information from many large datasets, MIT researchers have identified several new potential targets for treating or preventing Alzheimer's disease.

20 May 2025

Ground-breaking discovery reveals common master switch for brain-related diseases

The 21st edition of Sustainability Through Science and Technology Summit 2025 (SIPS 2025), dedicated to Prof. Aaron Ciechanover, Nobel Laureate in Chemistry, to be held in Cebu, Philippines, from 17-20 November 2025, has confirmed the participation of Davis Joseph as an invited summit plenary lecturer for his recent ground-breaking discovery of the common master switch for numerous brain-related diseases.

19 May 2025

Dementia patients in poorer areas of Quebec face unequal access to care

A new study has found stark differences in the dementia care received by people in richer and poorer neighborhoods in Quebec, despite the universal health-care system.

19 May 2025

New fruit fly study shows the whole-body impact of Alzheimer’s disease

While Alzheimer's disease is mostly considered a disorder of the brain, emerging evidence suggests that the condition also affects other organs of the body.

16 May 2025

New drug candidate disrupts the link between herpes virus and Alzheimer’s disease

Studies suggesting that certain viral infections may influence the onset of Alzheimer's diseases are gaining attention. In this context, a domestic research team has succeeded in breaking the link between viral infection and Alzheimer's disease using a new treatment candidate.

16 May 2025

Peptide nanostructures block amyloid buildup and boost neuron survival in lab tests

Researchers developed trehalose-functionalized peptide amphiphiles (TPAs) that self-assemble into supramolecular nanostructures and demonstrated these TPAs can inhibit amyloid beta aggregation. In vitro, TPAs significantly improved survival of human neurons exposed to amyloid-induced neurotoxicity, suggesting therapeutic potential for neurodegenerative diseases.

15 May 2025

Study finds fewer H. pylori infections among Parkinson’s patients

A large case-control study from China found that people with Parkinson’s disease were significantly less likely to test positive for Helicobacter pylori infection compared to controls. The findings suggest a potential protective link between this common stomach bacterium and Parkinson’s disease, though causality remains unproven.

15 May 2025

Sedentary behavior linked to increased Alzheimer's risk in older adults

Over 6 million Americans are impacted by Alzheimer's disease, and researchers from Vanderbilt University Medical Center and the University of Pittsburgh are discovering how lifestyle habits can impact the likelihood of developing the disease.

13 May 2025

Mitochondrial DNA editing offers new hope for neurodegenerative disease treatment

Mitochondrial DNA (mtDNA) editing has emerged as a revolutionary approach in the fight against neurodegenerative diseases (NDDs).

12 May 2025

CAR-T cell therapy linked to brain fog in cancer patients

After treatment with CAR-T cells - immune cells engineered to attack cancer - patients sometimes tell their doctors they feel like they have "brain fog," or forgetfulness and difficulty concentrating.

12 May 2025

High intake of ultra processed foods linked to early signs of Parkinson's

People who eat more ultra processed foods like cold breakfast cereal, cookies and hot dogs are more likely to have early signs of Parkinson's disease when compared to those who eat very few ultra processed foods, according to a study published in the May 7, 2025, online in Neurology, the medical journal of the American Academy of Neurology.

7 May 2025

Boosting glucose metabolism in glial cells reduces neurodegeneration in fruit flies

Researchers from Tokyo Metropolitan University have discovered that impaired glucose metabolism in glial cells, a type of cell in our nervous system, plays a key role in the degeneration caused by Alzheimer's disease.

5 May 2025