Phosphorylation News and Research

RSS

Researchers investigate the roles of STAT3α and STAT3β isoforms in aggressive breast cancer

A new research paper was published in Oncotarget's Volume 14 on April 24, 2023, entitled, "Differential silencing of STAT3 isoforms leads to changes in STAT3 activation."

26 Apr 2023

Study hints at the potential of sleep pills to slow or stop Alzheimer's disease progression

Sleep disturbances can be an early sign of Alzheimer's disease. Many people eventually diagnosed with Alzheimer's start experiencing difficulty falling and staying asleep years before cognitive problems such as memory loss and confusion emerge.

20 Apr 2023

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

A recent study reveals that DCAF1 is overexpressed and phosphorylates EZH2 in colon cancer cells.

18 Apr 2023

Ecological and evolutionary implications of the sharing of metabolites between different microbes in the gut microbiome

The researchers provide important insights into the cross-feeding mechanisms of nutrients in the gut microbiome and their impacts on host health.

18 Apr 2023

The interaction between white adipose tissue mitochondria and gut microbiota in obesity

Researchers explored the interaction of white adipose tissue mitochondria with gut microbiota in obesity.

4 Apr 2023

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

A recent review published in Biochemical Pharmacology summarized the ongoing research, providing insights into pathophysiology and emerging drugs for Alzheimer’s disease (AD).

31 Mar 2023

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Study outlines molecular mechanisms to aid the development of new therapies to manage obesity and associated health disorders.

29 Mar 2023

Grape polyphenols reduce angiogenesis in adipose tissue during overfeeding weight gain

A study published in the Journal of Nutritional Biochemistry investigated the changes in gene expressions during an overfeeding episode. It demonstrated that supplementation of grape polyphenols in healthy lean men modulates the expression of genes related to adipose tissue angiogenesis.

28 Mar 2023

Capsaicin and its health benefits

Researchers examine the health benefits associated with capsaicin, with a particular focus on how this compound impacts cognition and cardiovascular health.

28 Mar 2023

Pneumolysin toxin holds promise for developing therapies against Streptococcus pneumoniae

In a recent study published in the journal PLoS ONE, researchers in Spain performed a systematic review of pneumolysin (PLY) toxin as a molecular target to develop novel therapeutics against Streptococcus pneumoniae.

27 Mar 2023

How does soy consumption affect the risk of type 2 diabetes and cardiovascular diseases?

A higher intake of plant protein could effectively improve metabolic health and lower CVD mortality. Recently, scientists in China reviewed existing literature and conducted a meta-analysis to understand the association between increased soy consumption and the risk of T2D and CVDs. This review is available in the journal Nutrients.

15 Mar 2023

Research reveals the modulatory effect of anti-inflammatory metabolite on immune cells

Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which may lead to new therapeutic approaches to treating some autoimmune diseases.

15 Mar 2023

An emerging target for chronic kidney disease treatment - DNA-PKcs

A recent Nature Communications study suggested that DNA-PKcs could be a potential target for treating chronic kidney disease.

15 Mar 2023

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Researchers assessed the association between SARS-CoV-2 infection and DNA damage and cellular senescence.

14 Mar 2023

Inhibition of ACLY by 326E represents a promising strategy for treatment of hypercholesterolemia

This new article publication from Acta Pharmaceutica Sinica B, discusses the development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia.

9 Mar 2023

Study identifies a potential new treatment approach for acute myeloid leukemia

A team of researchers has discovered a potential therapeutic that can synergize with existing drugs to more effectively kill certain leukemia cells.

8 Mar 2023

Breaking apart certain proteins may offer a pathway to treat Alzheimer's diease

Certain diseases, including Alzheimer's, are currently considered "undruggable" because traditional small molecule drugs can't interfere with the proteins responsible for the illnesses.

1 Mar 2023

Apolipoprotein E4 promotes the development of Alzheimer’s disease

Researchers characterize the effects of neuronal apolipoprotein E4 on Alzheimer’s disease-associated pathology.

23 Feb 2023

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Researchers presented eight hallmarks of neurodegenerative diseases (NDDs), their in vivo biomarkers, and interactions to help categorize NDDs and specify patients within a specific NDD.

21 Feb 2023

Five teams awarded funding from the Starr Cancer Consortium to advance cancer research

Five teams led by Weill Cornell Medicine scientists have been awarded funding from the Starr Cancer Consortium in its 16th annual grant competition.

10 Feb 2023

Phosphorylation News and Research

Researchers investigate the roles of STAT3α and STAT3β isoforms in aggressive breast cancer

Study hints at the potential of sleep pills to slow or stop Alzheimer's disease progression

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

Ecological and evolutionary implications of the sharing of metabolites between different microbes in the gut microbiome

The interaction between white adipose tissue mitochondria and gut microbiota in obesity

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Grape polyphenols reduce angiogenesis in adipose tissue during overfeeding weight gain

Capsaicin and its health benefits

Pneumolysin toxin holds promise for developing therapies against Streptococcus pneumoniae

How does soy consumption affect the risk of type 2 diabetes and cardiovascular diseases?

Research reveals the modulatory effect of anti-inflammatory metabolite on immune cells

An emerging target for chronic kidney disease treatment - DNA-PKcs

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Inhibition of ACLY by 326E represents a promising strategy for treatment of hypercholesterolemia

Study identifies a potential new treatment approach for acute myeloid leukemia

Breaking apart certain proteins may offer a pathway to treat Alzheimer's diease

Apolipoprotein E4 promotes the development of Alzheimer’s disease

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Five teams awarded funding from the Starr Cancer Consortium to advance cancer research

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News