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Scientists revive diabetic beta cells, revealing a new path to restore insulin function

Researchers demonstrated that pancreatic β cells from type 2 diabetes donors can partially regain glucose responsiveness when cultured outside the diabetic environment. This recovery, driven by specific gene expression changes, identifies JAK inhibitors as potential therapeutic candidates to restore β-cell function.

14 Oct 2025

CN Bio launches all-in-one Organ-on-a-chip system

CN Bio, a leading provider of benchtop Organ-on-a-chip (OOC) solutions that accelerate drug discovery and development, today announced the launch of PhysioMimix® Core.

14 Oct 2025

Study uncovers key protein complex controlling sperm motility and male fertility

Infertility affects about one in six couples, and male factors account for roughly half of all cases-often because sperm don't swim well.

13 Oct 2025

Study offers new models for understanding the causes of chemo brain

Cancer is a challenging enough diagnosis, but many patients are dealt a second blow, even as they heal: "chemo brain."

13 Oct 2025

Discovery of unique brain cells sheds light on progressive multiple sclerosis

Scientists have identified an unusual type of brain cell that may play a vital role in progressive multiple sclerosis (MS), likely contributing to the persistent inflammation characteristic of the disease.

10 Oct 2025

How much caffeine is safe during pregnancy? New review finds no clear threshold

Caffeine's impact on pregnancy is nuanced; moderate consumption may not lead to major complications, but risks to fetal growth persist without a safe threshold.

10 Oct 2025

Obesity-linked fat vesicles accelerate amyloid aggregation in Alzheimer’s disease

Researchers discuss the role of extracellular vesicles as a potential link between obesity and Alzheimer’s disease.

9 Oct 2025

Decades of exercise found to train the immune system for better defense

In addition to strengthening the muscles, lungs, and heart, regular physical exercise also strengthens the immune system.

8 Oct 2025

State-of-the-art microchips help understand how sepsis and neurodegenerative diseases damage the brain

In lieu of animal experiments, researchers from the University of Rochester are using state-of-the-art microchips with human tissue to better understand how the brain operates under healthy conditions and is damaged through neurodegenerative diseases or conditions like sepsis.

7 Oct 2025

Azelastine nasal spray prevents COVID-19 and rhinovirus infections

Researchers discuss the effects of azelastine nasal spray on the rate of SARS-CoV-2 infection as compared to placebo.

6 Oct 2025

Zika virus exposure during pregnancy permanently shapes offspring's frontline immune cells

A Wayne State University study published in the Oct. 3, 2025, issue of Nature Communications revealed that Zika virus exposure during pregnancy causes long-term, sex-specific changes to a baby's immune system, particularly affecting the frontline immune cells that fight infection.

6 Oct 2025

Newly discovered mechanism helps leukemia cells to evade the immune system

A research team at Lund University in Sweden has discovered a mechanism that helps acute myeloid leukemia cells to evade the body's immune system.

3 Oct 2025

Tagomics publishes a new approach to genome-wide epigenomic profiling

Tagomics Ltd., a pioneering biomarker discovery and diagnostics company, today announced the publication of a peer-reviewed study in Cell Reports Methods, underpinning its epigenomic profiling technology, Active-Seq, the basis of Tagomics' Activace™ platform.

30 Sep 2025

Novel biosensing platform provides quantitative graded evaluation of mild to severe liver injury

Real-time monitoring of key biomarkers is a critical prerequisite for early disease diagnosis and personalized therapy. Early detection of liver function impairment particularly relies on the measurement of serum alanine aminotransferase (ALT).

29 Sep 2025

Precision probiotics lower blood sugar and cholesterol in mice

Researchers developed a precision probiotic cocktail comprising three Lactobacillus strains that improved glucose control, reduced weight gain, and lowered cholesterol levels in mice fed a high-fat diet. Metabolomic and microbiome analyses revealed host metabolic adaptations and beneficial shifts in gut bacteria, highlighting translational potential for future clinical trials.

28 Sep 2025

Clinical trial disproves claims that antioxidant supplement boosts male fertility

A large Dutch randomized clinical trial (SUMMER) found that a widely marketed antioxidant supplement (Impryl) did not improve ongoing pregnancy rates in men seeking fertility care. Instead, pregnancy success was significantly lower in the critical 4–6 month treatment window, raising safety concerns.

28 Sep 2025

Gut probiotic Christensenella tenuis reduces endotoxemia and improves metabolism in obese mice

This study is reported by the team of Professor Shuang-jiang Liu from Shandong University. The study reveals that the gut probiotic Christensenella tenuis significantly alleviates endotoxemia and metabolic disorders in a diet-induced obesity (DIO) mouse model by modulating gut bile acids (BAs) metabolism and suppressing lipopolysaccharide (LPS) translocation across the gut barrier.

26 Sep 2025

in vitro News and Research

Scientists revive diabetic beta cells, revealing a new path to restore insulin function

CN Bio launches all-in-one Organ-on-a-chip system

Study uncovers key protein complex controlling sperm motility and male fertility

Study offers new models for understanding the causes of chemo brain

Discovery of unique brain cells sheds light on progressive multiple sclerosis

How much caffeine is safe during pregnancy? New review finds no clear threshold

Obesity-linked fat vesicles accelerate amyloid aggregation in Alzheimer’s disease

Decades of exercise found to train the immune system for better defense

State-of-the-art microchips help understand how sepsis and neurodegenerative diseases damage the brain

Azelastine nasal spray prevents COVID-19 and rhinovirus infections

Zika virus exposure during pregnancy permanently shapes offspring's frontline immune cells

Newly discovered mechanism helps leukemia cells to evade the immune system

Tagomics publishes a new approach to genome-wide epigenomic profiling

Novel biosensing platform provides quantitative graded evaluation of mild to severe liver injury

Precision probiotics lower blood sugar and cholesterol in mice

Clinical trial disproves claims that antioxidant supplement boosts male fertility

Gut probiotic Christensenella tenuis reduces endotoxemia and improves metabolism in obese mice

Researchers develop tool to predict how patients will respond to common multiple sclerosis drug

Patient-derived organoids advance cancer therapy and vaccines

UPR modulators show promise in treating cancer-related bone disease

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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