Microbiology News and Research

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Scientists study cell’s reaction to Salmonella by visualizing protein chains at near-molecular level

With drug resistance being on the rise worldwide, bacterial infections pose one of the greatest global threats to human health. By deciphering the host-pathogen interaction on a molecular level, researchers hope to pave the way for new therapies.

10 May 2017

Study findings shed new light on evolution and interaction of ancient proteins

How did protein interactions arise and how have they developed? In a new study, researchers have looked at two proteins which began co-evolving between 400 and 600 million years ago.

9 May 2017

Despite availability of life-saving medicaiton, annual deaths due to fungal meningitis are still over 180,000

International HIV experts have reported approximately 250,000 fungal meningitis cases annually, in the AIDS report, sub-Saharan Africa contributing 73% of cases. Cryptococcus fungus causes fungal meningitis and usually affects individuals who are above 35 years old, affecting the tissues covering the brain and the spinal cord

8 May 2017

Study shows how influenza A hijacks human cellular machinery to replicate

Much is known about flu viruses, but little is understood about how they reproduce inside human host cells, spreading infection. Now, a research team headed by investigators from the Icahn School of Medicine at Mount Sinai is the first to identify a mechanism by which influenza A, a family of pathogens that includes the most deadly strains of flu worldwide, hijacks cellular machinery to replicate.

5 May 2017

Researchers show how Epstein-Barr virus manages to persist inside immune system's B cells

Viruses are notorious for taking over their host's operations and using them to their own advantage. But few human viruses make themselves quite as cozy as the Epstein-Barr virus, which can be found in an estimated nine out of ten humans without causing any ill effects.

3 May 2017

Study shows how probiotic improves integrity of the GI epithelial cell wall in HIV patients

A newly released study published in the Journal of Immunity, Inflammation and Disease and conducted by the Sapienza University of Rome, Italy, found a multi-strain, high concentration, probiotic formulation that helped reconstitute the physical and immunological integrity of the gastrointestinal lining in HIV-1-positive patients on antiretroviral therapy.

3 May 2017

New study shows that gene editing technology can shut down HIV-1 replication in animals

A permanent cure for HIV infection remains elusive due to the virus's ability to hide away in latent reservoirs. But now, in new research published in print May 3 in the journal Molecular Therapy, scientists at the Lewis Katz School of Medicine at Temple University and the University of Pittsburgh show that they can excise HIV DNA from the genomes of living animals to eliminate further infection.

2 May 2017

Penn State establishes new $2.4-million Biomedical Big Data to Knowledge Training Program

A new $2.4-million program for graduate students seeking to contribute to breakthrough discoveries in medicine and biology has been established at Penn State University with nearly $1.4 million in funding from the National Library of Medicine of the U.S. National Institutes of Health and more than $1 million from Penn State.

28 Apr 2017

Researchers find persistence of Zika virus in cerebrospinal fluid, lymph nodes of rhesus monkeys

Zika virus can persist in cerebrospinal fluid (CSF), lymph nodes and colorectal tissue of infected rhesus monkeys for weeks after the virus has been cleared from blood, urine and mucosal secretions, according to a study published online in Cell.

28 Apr 2017

New class of drugs offers hope against antibiotic resistance

Polyphor today presented promising data for their novel class of antibiotics, the Outer Membrane Protein Targeting Antibiotics (OMPTA). This is the first new class of antibiotic against Gram-negative pathogens to reach advanced clinical development in over 40 years.

26 Apr 2017

Combination of genetics and experience gives each individual a unique sense of smell, study finds

Researchers from the Wellcome Trust Sanger Institute and their collaborators have shown that receptors in the noses of mice exposed to certain smells during life are different to genetically similar mice that lived without those smells.

25 Apr 2017

New test can quickly and accurately diagnose dangerous colistin-resistant bacteria

New research suggests it is possible to quickly and accurately diagnose some the most dangerous and drug-resistant types of bacterial infections, using equipment already owned by most hospitals.

24 Apr 2017

Testing for molecular markers in urine could reveal early signs of kidney transplant failure

Testing for molecular markers in the urine of kidney transplant patients could reveal whether the transplant is failing and why, according to research presented at the 27th European Congress of Clinical Microbiology and Infectious Diseases.

24 Apr 2017

Research findings may help doctors to better treat bloodstream infections with fewer side effects

Patients with bloodstream infections could avoid treatment with a combination of antimicrobial therapies if they are given the right drug as early as possible and if they are classified as at low risk of death.

24 Apr 2017

Antibiotic-resistant bacteria in patients’ urine or stools linked to increased risk of drug-resistant sepsis

People who have recently been found to have drug-resistant bacteria in their urine or stool samples have a greatly increased risk of developing a bloodstream infection that is also resistant to certain antibiotics, according to a study presented at the 27th European Congress of Clinical Microbiology and Infectious Diseases.

24 Apr 2017

Mice study yields important clues about protective role of Clostridia strains

Hundreds of thousands of babies worldwide die every year from infections that ravage their digestive systems – including those caused by Salmonella and E. coli bacteria. Millions more get sick.

21 Apr 2017

Fungi have immense potential for production of pharmaceutical compounds

Fungi are a potential goldmine for the production of pharmaceuticals. This is shown by researchers at Chalmers University of Technology, who have developed a method for finding new antibiotics from nature's own resources.

20 Apr 2017

Researchers report new evidence that defective HIV proviruses distract immune system

Researchers at Johns Hopkins and George Washington universities report new evidence that proteins created by defective forms of HIV long previously believed to be harmless actually interact with our immune systems and are actively monitored by a specific type of immune cell, called cytotoxic T cells.

19 Apr 2017

Researchers show how dengue virus employs multiple tactics to evade immune detection

For the human body to mount an immune response to a viral infection, host cells must identify the viral invader and trigger a signaling pathway. This signal then prompts the immune system to attack and subdue the pathogen.

19 Apr 2017

Bacteriophages may help combat antibiotic-resistant 'superbugs'

Viruses that specifically kill bacteria, called bacteriophages, might one day help solve the growing problem of bacterial infections that are resistant to antibiotic treatment.

18 Apr 2017

Microbiology News and Research

Scientists study cell’s reaction to Salmonella by visualizing protein chains at near-molecular level

Study findings shed new light on evolution and interaction of ancient proteins

Despite availability of life-saving medicaiton, annual deaths due to fungal meningitis are still over 180,000

Study shows how influenza A hijacks human cellular machinery to replicate

Researchers show how Epstein-Barr virus manages to persist inside immune system's B cells

Study shows how probiotic improves integrity of the GI epithelial cell wall in HIV patients

New study shows that gene editing technology can shut down HIV-1 replication in animals

Penn State establishes new $2.4-million Biomedical Big Data to Knowledge Training Program

Researchers find persistence of Zika virus in cerebrospinal fluid, lymph nodes of rhesus monkeys

New class of drugs offers hope against antibiotic resistance

Combination of genetics and experience gives each individual a unique sense of smell, study finds

New test can quickly and accurately diagnose dangerous colistin-resistant bacteria

Testing for molecular markers in urine could reveal early signs of kidney transplant failure

Research findings may help doctors to better treat bloodstream infections with fewer side effects

Antibiotic-resistant bacteria in patients’ urine or stools linked to increased risk of drug-resistant sepsis

Mice study yields important clues about protective role of Clostridia strains

Fungi have immense potential for production of pharmaceutical compounds

Researchers report new evidence that defective HIV proviruses distract immune system

Researchers show how dengue virus employs multiple tactics to evade immune detection

Bacteriophages may help combat antibiotic-resistant 'superbugs'

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