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Glycome shift in epidermal stem cells could serve as potential biomarker of aging

Age shows nowhere better than on the skin. The ravages of time on skin and the epidermal stem cells that differentiate to replenish its outer layer have been hypothesized, but there has been no method to evaluate their aging at the molecular level.

21 Jul 2020

Antibody profile and estimated seroprevalence in COVID-19 infection

A new Swedish study published on the preprint server medRxiv in July 2020 describes the results of using highly sensitive and specific anti-spike antibody tests in a cohort of patients with COVID-19 over a range of disease severity.

21 Jul 2020

Researchers receive $1.3 million grant to develop better treatments for Alzheimer's disease

Innovators at Purdue University have received new support as they work to develop solutions to what U.S. military officials call an alarming trend in dementia among wounded soldiers. The same researchers also seek solutions to better treat Alzheimer's disease.

21 Jul 2020

Reproductive outcomes predicted by label-free imaging technique

Researchers at the Beckman Institute for Advanced Science and Technology and the Department of Animal Sciences have collaborated to develop a new technique that can be used to determine the fertility of sperm samples.

20 Jul 2020

Study: Luminescent substance enables accurate observation of different areas of the organism

A luminescent fluid made up of nanoparticles that allows more accurate observation of different areas of the organism has been developed by a research team from the Colloidal Materials group of the Institute of Materials Science of Seville (a CSIC-University of Seville joint centre) in collaboration with the Institute of Materials Science of Aragon, the Andalusian Centre of Medicine and Biotechnology (BIONAND) and the Spanish National Accelerator Centre (CNA).

20 Jul 2020

SARS-CoV-2 protein effectively shuts down production of proteins in the host, study shows

A detailed study of a SARS-Cov-2 protein, Nsp1, with a central role in weakening the host anti-viral immune response shows that it effectively shuts down production ofproteins in the host.

17 Jul 2020

Groundbreaking technology could enhance therapeutic efficiency of nanomedicines

Researchers from the Moscow Institute of Physics and Technology and their colleagues from Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry and Prokhorov General Physics Institute of the Russian Academy of Sciences have developed a breakthrough technology to resolve a key problem that has prevented the introduction of novel drugs into clinical practice for decades.

17 Jul 2020

Blood vessels communicate with sensory neurons to regulate their proliferation

Researchers at Pompeu Fabra University have shown for the first time that blood vessels communicate with neurons in the peripheral nervous system, regulating their proliferation and differentiation.

16 Jul 2020

Compelling study shows heparin may protect against COVID-19

A compelling new study conducted by an international team of researchers has demonstrated that the widely used blood-thinning medication - heparin - can block infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

16 Jul 2020

Selective statins may reduce SARS-CoV-2 cell entry and inhibit infection

Statins are a class of drugs often used to control high cholesterol levels in obesity. Now, a study published on the preprint server medRxiv* in July 2020 suggests that statins do not aggravate the risk of COVID-19 infection and may have a small beneficial effect in some cases.

16 Jul 2020

Nanotechnology plays major role in COVID-19 vaccine development

From mRNA vaccines entering clinical trials, to peptide-based vaccines and using molecular farming to scale vaccine production, the COVID-19 pandemic is pushing new and emerging nanotechnologies into the frontlines and the headlines.

15 Jul 2020

Strong evidence several FDA approved drugs block SARS-CoV-2 in relevant cell-lines and human organoids

Now, a new study describes how compounds that restore the normal transcriptional conditions following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be used to reduce viral load without neutralizing the virus entry into the host cell.

15 Jul 2020

Llama nanobodies block SARS-CoV-2 infection in vitro

Now, a team of scientists at the United Kingdom's Rosalind Franklin Institute may have a surprising solution for the coronavirus pandemic, which has killed more than 574,000 people worldwide.

14 Jul 2020

Absolute Antibody and University of Zurich partner to offer novel SARS-CoV-2 sybodies

Absolute Antibody Ltd., an industry-leading provider of recombinant antibody products and services, today announced a partnership with University of Zurich to offer synthetic nanobodies against the receptor binding domain (RBD) of SARS-CoV-2, the coronavirus that causes COVID-19.

From Absolute Antibody Ltd 14 Jul 2020

Vav3 protein promotes cystic fibrosis, shows study

Cystic fibrosis, one of the most common genetic diseases in Switzerland, causes severe respiratory and digestive disorders.

14 Jul 2020

New theranostic agents show efficacy for precision diagnosis, treatment of prostate cancer

Researchers have developed a new pair of agents that show exceptional effectiveness for precision diagnosis and treatment of prostate cancer in preclinical studies.

13 Jul 2020

EKF introduces novel molecular transport media for dual COVID-19 and influenza sampling

EKF Diagnostics the global in vitro diagnostics company, announces that it has added a novel viral transport media for the safe sample handling and testing of multiple infectious diseases from a single swab to its product range.

From EKF Diagnostics 13 Jul 2020

FIND and Unitaid launch call for EOI to fill major diagnostic gaps in COVID-19 detection

The Foundation for Innovative New Diagnostics and Unitaid announced today that the organizations have launched a call for expressions of interest to accelerate the availability and manufacturing scale-up of rapid diagnostic tests for the detection of SARS-CoV-2 antigens. Reliable, affordable Ag RDTs have been identified as key tools in the global response to COVID-19, as they could enable robust detection of active SARS-CoV-2 infection for both patient management and contact tracing purposes in decentralized settings.

10 Jul 2020

LGC acquires The Native Antigen Company, strengthening its offer to the IVD sector

Today, LGC announced the acquisition of The Native Antigen Company (NAC), one of the world’s leading suppliers of high quality infectious disease antigens and antibodies.

9 Jul 2020

Tracing adaptation to ACE2 use in sarbecoviruses

A detailed study published on the preprint server bioRxiv in July 2020 argues that recombination accounts for the appearance of the ability of both SARS-CoV and SARS-CoV-2 to use the human angiotensin-converting enzyme (hACE) 2 as the binding receptor mediating viral infection of human cells.

8 Jul 2020

in vitro News and Research

Glycome shift in epidermal stem cells could serve as potential biomarker of aging

Antibody profile and estimated seroprevalence in COVID-19 infection

Researchers receive $1.3 million grant to develop better treatments for Alzheimer's disease

Reproductive outcomes predicted by label-free imaging technique

Study: Luminescent substance enables accurate observation of different areas of the organism

SARS-CoV-2 protein effectively shuts down production of proteins in the host, study shows

Groundbreaking technology could enhance therapeutic efficiency of nanomedicines

Blood vessels communicate with sensory neurons to regulate their proliferation

Compelling study shows heparin may protect against COVID-19

Selective statins may reduce SARS-CoV-2 cell entry and inhibit infection

Nanotechnology plays major role in COVID-19 vaccine development

Strong evidence several FDA approved drugs block SARS-CoV-2 in relevant cell-lines and human organoids

Llama nanobodies block SARS-CoV-2 infection in vitro

Absolute Antibody and University of Zurich partner to offer novel SARS-CoV-2 sybodies

Vav3 protein promotes cystic fibrosis, shows study

New theranostic agents show efficacy for precision diagnosis, treatment of prostate cancer

EKF introduces novel molecular transport media for dual COVID-19 and influenza sampling

FIND and Unitaid launch call for EOI to fill major diagnostic gaps in COVID-19 detection

LGC acquires The Native Antigen Company, strengthening its offer to the IVD sector

Tracing adaptation to ACE2 use in sarbecoviruses

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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