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Novel computational tool helps analyze complex genetic regions

GeneDx (Nasdaq: WGS), a leader in delivering improved health outcomes through genomic and clinical insights, today published a paper in Nature Methods, titled "Multiscale analysis of pangenomes enables improved representation of genomic diversity for repetitive and clinically relevant genes," in which researchers developed a new computational tool, the PanGenome Research-Tool Kit (PGR-TK), for scalable analysis of clinically relevant genes that were previously too complex to analyze.

27 Jun 2023

Study: Cancer patients with unmet supportive care needs more likely to experience worse outcomes

Cancer patients with unmet supportive care needs are more likely to experience worse clinical outcomes, including more emergency department (ED) visits and hospitalizations, according to new research from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine.

26 Jun 2023

Dairy milk is a key source of important nutrients, but has environmental trade-offs

Along with all global sectors, the dairy industry is working to reduce its environmental impact as we look toward a shared 2050 net zero future.

26 Jun 2023

New study offers clues on how to future-proof covid-19 vaccines

New research examining how frequently our bodies produce broadly neutralizing antibodies (bnAbs) capable of thwarting a range of SARS-CoV-2 variants offers clues on the strategy tweaks that could potentially future-proof COVID-19 vaccines.

26 Jun 2023

Mediation may not be effective in resolving disputes over child's medical treatment

The role of mediation in preventing disputes between parents and doctors about a seriously ill child's medical treatment from escalating to litigation may be more limited than hoped for, suggests an analysis of rulings, published online in the Archives of Disease in Childhood.

26 Jun 2023

New study shows promise for diphenyl ditelluride as anti-cancer drug

A new research paper was published in Oncotarget's Volume 14 on June 21, 2023, entitled, "Diphenyl ditelluride anticancer activity and DNA topoisomerase I poisoning in human colon cancer HCT116 cells."

26 Jun 2023

Sense of purpose in life can offer protection against loneliness

A new study co-authored by Patrick Hill, associate professor of psychological and brain sciences, offers an important message for our times: A sense of purpose in life - whether it's a high-minded quest to make a difference or a simple hobby with personal meaning - can offer potent protection against loneliness.

26 Jun 2023

Anchoring bias in emergency medicine leads to missed diagnosis of pulmonary embolism

Finding evidence of what is known as "anchoring bias," UCLA-led research suggests that patients with congestive heart failure experiencing shortness of breath are less likely to be tested in the emergency department for a potentially fatal pulmonary embolism, or a blood clot in the lung, when the reason for the visit noted during the initial emergency department check-in process specifically mentions congestive heart failure instead of the broader "shortness of breath".

26 Jun 2023

Novel biomaterials approach reveals how mechanical forces shape T cell fate

The successful campaign of adoptive T cell therapies, a type of immunotherapy in which immune T cells are collected from a patient, enhanced outside of the body, and reinfused back into the same patient, especially against blood cancers is well under way.

26 Jun 2023

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

Researchers at The University of Texas MD Anderson Cancer have engineered a new model of aggressive renal cell carcinoma (RCC), highlighting molecular targets and genomic events that trigger chromosomal instability and drive metastatic progression.

26 Jun 2023

Personalized dosing improves outcomes for men with metastatic castration-resistant prostate cancer

By monitoring early-response biomarkers in men undergoing 177Lu-PSMA prostate cancer treatment, physicians can personalize dosing intervals, significantly improving patient outcomes.

26 Jun 2023

New computational technique shows promise for identifying different subtypes of Alzheimer's disease

A new computational technique that combines genomic and tau PET imaging data promises a more personalized approach for subtyping Alzheimer's disease.

26 Jun 2023

Researchers pinpoint a key feature that leads to aggressive spread of colon cancer

In a significant development in the fight against fatal cancers, University of Otago researchers have pinpointed a key feature that leads to the aggressive spread of colon cancer.

26 Jun 2023

Lean body mass and age predict how quickly women eliminate alcohol

The rate at which women eliminate alcohol from their bloodstream is largely predicted by their lean body mass, although age plays a role, too, scientists found in a new study.

26 Jun 2023

World-renowned researcher receives top award for contributions to clinical psychopharmacology

Dennis Charney, MD, the Anne and Joel Ehrenkranz Dean of the Icahn School of Medicine at Mount Sinai and President for Academic Affairs of the Mount Sinai Health System, has received the prestigious Donald Klein Lifetime Achievement Award from the American Society for Clinical Psychopharmacology (ASCP).

26 Jun 2023

Research News and Research

Novel computational tool helps analyze complex genetic regions

Study: Cancer patients with unmet supportive care needs more likely to experience worse outcomes

Dairy milk is a key source of important nutrients, but has environmental trade-offs

New study offers clues on how to future-proof covid-19 vaccines

Mediation may not be effective in resolving disputes over child's medical treatment

New study shows promise for diphenyl ditelluride as anti-cancer drug

Sense of purpose in life can offer protection against loneliness

Anchoring bias in emergency medicine leads to missed diagnosis of pulmonary embolism

Novel biomaterials approach reveals how mechanical forces shape T cell fate

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

Personalized dosing improves outcomes for men with metastatic castration-resistant prostate cancer

New computational technique shows promise for identifying different subtypes of Alzheimer's disease

Researchers pinpoint a key feature that leads to aggressive spread of colon cancer

Lean body mass and age predict how quickly women eliminate alcohol

World-renowned researcher receives top award for contributions to clinical psychopharmacology

UCalgary researchers discover how Leishmania parasites hide within the body

Researchers identify a potential new drug for NASH-related fibrosis

Smart Cuff: A single device to measure multiple cardiac functions

Research unveils crucial insights into the brain's potential ability to regulate fentanyl consumption

Study sheds new light on the relationship between gut microbiome and autism

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

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