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Low-salt diets may increase CVD risk and death compared to average salt consumption

A large worldwide study has found that, contrary to popular thought, low-salt diets may not be beneficial and may actually increase the risk of cardiovascular disease (CVD) and death compared to average salt consumption.

23 May 2016

New study may contribute to ongoing debate on fortification program

Fortifying the U.S. food supply with folic acid was not associated with a decline in certain birth defects that researchers expected to see in California, according to a new study from the Stanford University School of Medicine.

23 May 2016

Robotic-assisted radical prostatectomy may reduce risk of blood loss, prolonged hospital stays in obese men

In obese prostate cancer patients, robotic-assisted surgery to remove the prostate reduces the risk of blood loss and prolonged hospital stays, a Loyola Medicine study has found.

23 May 2016

ULK1, ULK2 enzymes play key role in maintaining cellular homeostasis

Researchers at St. Jude Children's Research Hospital have uncovered how two enzymes, ULK1 and ULK2, which are best known for their role in the degradation and recycling of proteins, control the trafficking of specific proteins.

23 May 2016

New microfluidic device helps extract rare target cells from background cells

A team of researchers from University of Cincinnati in Cincinnati, OH have developed a novel microfluidic device, which combines the inertial effect of fluid and microscale vortices generated in microchambers, to achieve simultaneous double sorting of rare target cells and removal of background cells.

23 May 2016

New, easy-to-use method for rapid testing of neutrophil chemotaxis

A team of researchers from the University of Manitoba in collaboration with local clinical scientists in Winnipeg, Canada, have developed a new method for rapid neutrophil chemotaxis test directly from a small drop of whole blood using a microfluidic system.

23 May 2016

Pre-procedural use of antiplatelet therapy becoming less routine in heart attack treatment

Doctors worried about dangerous blood clots in patients undergoing a coronary artery procedure— such as angioplasty to treat a heart attack — will often administer antiplatelet therapy to head off complications.

22 May 2016

Administering TXA through IV and IA can reduce blood loss following total knee replacement

A new study appearing in the Journal of Bone and Joint Surgery found that administering tranexamic acid (TXA) both intravenously (IV) and injected at the surgical site (intra-articular administration, or IA) reduced blood loss by 37 percent, compared to IV alone, following total knee replacement (TKR).

22 May 2016

Phase I study of triple drug combination shows promise in multiple myeloma patients

PharmaMar announces the positive results from a Phase I study of plitidepsin in combination with bortezomib and dexamethasone in patients with relapsed and/or refractory multiple myeloma.

21 May 2016

Intensive blood pressure lowering therapies can cut heart disease risk in older adults

Intensive therapies to reduce high blood pressure can cut the risk of heart disease in older adults without increasing the risk for falls, according to doctors at Wake Forest Baptist Medical Center.

21 May 2016

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Prediabetes is associated with increased risk of diabetes, cardiovascular disease, dementia and cancer. However, the disease risk considerably varies among subjects.

21 May 2016

SPRINT supports stringent BP goals for elderly

Analysis of SPRINT participants older than 75 years shows that they too benefitted from an intensive blood pressure target of 120 mmHg.

20 May 2016

Breakthrough technique removes potentially harmful additives from common injectable drugs

Bring the drugs, hold the suds. That summarizes a promising new drug-making technique designed to reduce serious allergic reactions and other side effects from anti-cancer medicine, testosterone and other drugs that are administered with a needle.

20 May 2016

AstraZeneca, MedImmune to provide update on extensive oncology pipeline at ASCO 2016

AstraZeneca and its global biologics research and development arm, MedImmune, will provide an update on their extensive oncology pipeline at the annual meeting of the American Society of Clinical Oncology in Chicago, USA, on 3-7 June 2016.

20 May 2016

Researchers identify single RCAN1 gene responsible for onset of type 2 diabetes

RESEARCHERS have identified the gene they believe is responsible for the onset of type 2 diabetes, sparking hope for treatments to prevent and possibly reverse the progressive condition.

20 May 2016

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Chronix Biomedical, Inc., a developer of blood-based molecular diagnostics, today announces positive data from a blinded proof of concept clinical study, assessing the utility of tumor cell-free DNA as a predictor of therapeutic response to immunotherapy after the first cycle of treatment in eight different types of cancer.

20 May 2016

Study examines effects of ultra-low doses of glyphosate on gene expression profiles

Glyphosate, often sold under the brand name of Roundup, is the world's most widely used weed-killer. While Glyphosate has approval from regulatory bodies worldwide, there are growing concerns about its possible adverse health effects.

20 May 2016

Older, frail hypertensive adults could benefit from intensive lowering of blood pressure

Adults with hypertension who are age 75 years and older, including those who are frail and with poor overall health, could benefit from lowering their blood pressure below current medical guidelines.

20 May 2016

Combined public health intervention could help manage CKD in developing countries

A simple and inexpensive public health intervention helped prevent many cases of chronic kidney disease (CKD) in Pakistan. The intervention, which is described in a study in the Clinical Journal of the American Society of Nephrology, will be especially helpful for protecting the kidney health of people living in developing countries.

20 May 2016

Study finds that ACS NSQIP Surgical Risk Calculator has excellent calibration

The American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator accurately estimates the chance of a patient experiencing postoperative complications, and its performance can improve with recalibration of the tool according to research findings appearing online in the Journal of the American College of Surgeons in advance of print publication.

20 May 2016

Blood News and Research

Low-salt diets may increase CVD risk and death compared to average salt consumption

New study may contribute to ongoing debate on fortification program

Robotic-assisted radical prostatectomy may reduce risk of blood loss, prolonged hospital stays in obese men

ULK1, ULK2 enzymes play key role in maintaining cellular homeostasis

New microfluidic device helps extract rare target cells from background cells

New, easy-to-use method for rapid testing of neutrophil chemotaxis

Pre-procedural use of antiplatelet therapy becoming less routine in heart attack treatment

Administering TXA through IV and IA can reduce blood loss following total knee replacement

Phase I study of triple drug combination shows promise in multiple myeloma patients

Intensive blood pressure lowering therapies can cut heart disease risk in older adults

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

SPRINT supports stringent BP goals for elderly

Breakthrough technique removes potentially harmful additives from common injectable drugs

AstraZeneca, MedImmune to provide update on extensive oncology pipeline at ASCO 2016

Researchers identify single RCAN1 gene responsible for onset of type 2 diabetes

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Study examines effects of ultra-low doses of glyphosate on gene expression profiles

Older, frail hypertensive adults could benefit from intensive lowering of blood pressure

Combined public health intervention could help manage CKD in developing countries

Study finds that ACS NSQIP Surgical Risk Calculator has excellent calibration

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