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Protein synaptotagmin-IV helps maintain an efficient brain

The instruction manual for maintaining an efficient brain may soon include a section on synaptotagmin-IV (Syt-IV), a protein known to influence learning and memory, thanks to a study by University of Wisconsin-Madison researchers.

18 May 2009

The impact of third hand smoke on risk for genetic mutations wins Addiction Science Award

A resourceful study into the effect of third hand smoke upon the risk for genetic mutations in fruit flies won the top Addiction Science Award at this year's Intel International Science and Engineering Fair (ISEF), the world's largest science competition for high school students.

18 May 2009

New system to deliver siRNA into primary cells

In technology that promises to one day allow drug delivery to be tailored to an individual patient and a particular cancer tumor, researchers at the University of California, San Diego School of Medicine, have developed an efficient system for delivering siRNA into primary cells.

17 May 2009

Genetic signature may predict patient response to GIST therapy

Researchers at Fox Chase Cancer Center uncovered a genetic pattern that may help predict how gastrointestinal stromal tumor (GIST) patients respond to the targeted therapy imatinib mesylate (Gleevec). Moreover, their findings point to genes that could be suppressed in order to make these tumors respond more readily to imatinib.

15 May 2009

Old diabetes drug Metformin teaches experts new tricks

Research from the Johns Hopkins Children's Center reveals that the drug most commonly used in type 2 diabetics who don't need insulin works on a much more basic level than once thought, treating persistently elevated blood sugar - the hallmark of type 2 diabetes - by regulating the genes that control its production.

15 May 2009

Many Americans support increased domestic funding to address HIV/AIDS, report says

Many Americans support increased funding to address HIV/AIDS in the U.S. according to a report released Wednesday for the National AIDS Coordinating Committee with support from the MAC AIDS Fund, Reuters Health reports.

14 May 2009

Eliminating Rhode Island's HIV test signature requirement would boost prevention, treatment efforts

Rhode Island's legislature currently is considering a bill (H.B. 5415) that would eliminate a requirement that a person sign his or her name before undergoing an HIV test, which "would essentially make getting an HIV test more like getting any other medical test," Brian Alverson, assistant pediatrics professor at Brown University's Alpert Medical School and head of the Section of Pediatric Hospitalists at Hasbro Children's Hospital, writes in a Providence Journal opinion piece.

5 May 2009

Imiquimod, a topical cream, may help treat skin cancer

In a case study of a type of melanoma skin cancer typically found on chronically sun-exposed skin, Saint Louis University researchers found that imiquimod, a topical cream, produced good results for patients when used together with surgery to treat the cancer, potentially helping doctors cut less.

30 Apr 2009

Women with epilepsy should avoid taking the drug valproate during pregnancy

New guidelines developed by the American Academy of Neurology and the American Epilepsy Society show it's relatively safe for women with epilepsy to become pregnant, but caution must be taken, including avoiding one particular epilepsy drug that can cause birth defects.

27 Apr 2009

Organic biosensor detects onset of acute myocardial ischemia

Engineering researchers at the University of Arkansas have fabricated and tested a unique biosensor that measures concentrations of potassium and hydrogen ions in the human heart with high specificity.

22 Apr 2009

Discovery of genetic pattern that may predict response to Gleevec in GIST

22 Apr 2009

Ardea Biosciences announces positive results from a phase 1 study of lead candidate for hyperuricemia and gout

Ardea Biosciences, Inc. has announced positive results from a Phase 1 study in normal, healthy volunteers of RDEA594, its lead product candidate for the treatment of hyperuricemia and gout, and a pilot Phase 2a proof-of-concept study in gout patients of RDEA594's prodrug, RDEA806 (RDEA806 is converted to RDEA594 in the body).

20 Apr 2009

Discovery of new chemical reaction for DNA production in bacteria and viruses

A team of researchers has discovered a new chemical reaction for producing one of the four nucleotides, or building blocks, needed to build DNA.

16 Apr 2009

Births by Cesarean section rose by more than 40 percent in 10 years

The percentage of pregnant women undergoing a repeat Cesarean section (C-section) delivery jumped from 65 percent to 90 percent between 1997 and 2006, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

16 Apr 2009

A good midwife makes giving birth at home as safe as in hospital

Researchers in the Netherlands say giving birth at home with a midwife is as safe as doing so in hospital.

16 Apr 2009

New updated clinical guidelines for HIV-associated opportunistic infections

The first complete update in five years of the U.S. guidelines for preventing and treating HIV-associated opportunistic infections has been released by the National Institutes of Health and the Centers for Disease Control and Prevention in cooperation with the HIV Medicine Association of the Infectious Diseases Society of America (IDSA).

16 Apr 2009