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EvOx Therapeutics raises £10m to target new therapeutic system for untreatable diseases

Oxford spinout EvOx Therapeutics will harness the body’s own precision communications system to deliver drugs to specific parts of the body, with the aim of treating conditions which are currently untreatable including those affecting the brain, as well as autoimmune diseases and cancers.

11 May 2016

Chronic use of antacid drugs may speed up aging of blood vessels

Chronic use of some drugs for heartburn and gastroesophageal reflux (GERD) speeds up the aging of blood vessels, according to a published paper in Circulation Research, an American Heart Association journal.

11 May 2016

Non-invasive 3-D virtual heart assessment tool can help predict arrhythmia risk in patients

When electrical waves in the heart run amok in a condition called arrhythmia, sudden death can occur. To save the life of a patient at risk, doctors currently implant a small defibrillator to sense the onset of arrhythmia and jolt the heart back to a normal rhythm.

11 May 2016

Oral regimens could offer simple solution for severe hyperglycaemia

Study findings indicate that oral treatments could offer a simpler alternative to upfront insulin for patients who have severe hyperglycaemia at the time of diagnosis with Type 2 diabetes.

10 May 2016

Potential new intraocular treatment based on RAS manipulation can prevent or reverse diabetic retinopathy

Pathologic changes of the retina caused by diabetes is the leading cause of blindness in working adults. Diabetic retinopathy has no known cure, treatment options are inadequate, and prevention strategies offer limited protection. In the first of its kind, a report in The American Journal of Pathology describes a potential new intraocular treatment based on manipulating the renin angiotensin system (RAS) that both prevents and reverses some characteristics of diabetic retinopathy in a mouse model.

10 May 2016

Sophisticated technology helps model and simulate optimal dose for pediatric ependymoma patients

St. Jude Children's Research Hospital scientists have used sophisticated pharmacologic modeling and simulation to translate preclinical findings into a successful phase I clinical trial of a chemotherapy agent for treatment of ependymoma. The research marked the first time the approach has been used to calculate drug doses for a clinical trial in pediatric brain tumor patients.

10 May 2016

Scientists discover new genetic information about development of breast cancer

SCIENTISTS have unearthed crucial new genetic information about how breast cancer develops and the genetic changes which can be linked to survival, according to a Cancer Research UK-funded study published in Nature Communications today (Tuesday).

10 May 2016

UCLA neurologist highlights steps that can help Americans reduce stroke risk

Getting more exercise, giving up cigarettes and monitoring cholesterol and blood pressure are a few steps Americans can take to reduce their risk of stroke, says Doojin Kim, MD, a neurologist at UCLA Medical Center, Santa Monica who often treats patients who have suffered a stroke, the No. 4 cause of death and the No. 1 cause of adult disability in the U.S.

10 May 2016

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

In most cases, tumors of the thymus gland are removed by surgical resection. However, they recur after a few years in up to one third of patients. A research team headed up by thoracic surgeon Bernhard Moser of the Thoracic Surgery Department at MedUni Vienna has successfully demonstrated that these tumors form heat-shock proteins. The lower the concentration of these proteins, the more quickly tumors recur. The study has been published in the leading journal Scientific Reports.

10 May 2016

Digital health: putting patients at the center. An interview with Roz Davies

In England alone the NHS sees 1 million patients every 36 hours and there are 3 million volunteers across health and social care many of whom are motivated by their personal experience of healthcare services.

10 May 2016

Videogame addiction may impact sleep habits, obesity and cardio-metabolic health among children and teens

Some children and youth with high videogame addiction tendencies may be at risk of sleep deprivation and disorders associated with obesity and poor cardio-metabolic health, Hamilton researchers have found.

10 May 2016

Experimental vaccine protects healthy U.S. adults from malaria infection for more than one year

An experimental malaria vaccine protected a small number of healthy, malaria-naïve adults in the United States from infection for more than one year after immunization, according to results from a Phase 1 trial described in the May 9th issue of Nature Medicine.

10 May 2016

Caltech researchers discover new potential cause for Crohn's disease

The community of beneficial bacteria that live in our intestines, known as the gut microbiome, are important for the development and function of the immune system. There has been growing evidence that certain probiotics--therapies that introduce beneficial bacteria into the gut--may help alleviate some of the symptoms of intestinal disorders such as Crohn's disease.

10 May 2016

CoSTREAM project aims to find common mechanisms, pathways in stroke and Alzheimer's disease

Stroke and Alzheimer's disease are major diseases imposing a huge burden on aging societies. It has long been recognized that stroke and Alzheimer's disease often co-occur, and it has been speculated that the two disorders have an overlapping pathogenesis.

10 May 2016

New set of practice guidelines from WMS may help in treatment, prevention of drowning

Drowning is a global threat to human health. Each year, more than 372,000 people die as a result of drowning, with many of those deaths being preventable by simple water safety measures. In order to arm professionals with the most up-to-date clinical protocols, the Wilderness Medical Society has issued a new set of practice guidelines for both the treatment and prevention of drowning, published in the society's official journal, Wilderness and Environmental Medicine.

10 May 2016

Food deprivation may help treat fatty liver disease

Scientists at Helmholtz Zentrum München have new information on what happens at the molecular level when we go hungry. Working with the Deutsches Zentrum für Diabetesforschung and the Deutsches Krebsforschungszentrum they were able to show that upon deprivation of food a certain protein is produced that adjusts the metabolism in the liver.

9 May 2016

Research shows spleen MZ B cells produce signaling proteins involved in inflammatory responses

The inability to adequately respond to infection can cause a whole-body state of inflammation known as sepsis. This can eventually lead to systemic inflammatory response syndrome (SIRS), and even death.

9 May 2016

Controlling heart cells using a laser: an interview with Prof. Konstantin Agladze

We control their electrical activity. Cardiac cells are capable of producing and transmitting electric signals through changes in a cell membrane potential.

9 May 2016

Scientists develop low-cost, easy-to-use diagnostic platform to detect Zika virus

University of Toronto Assistant Professor of Pharmacy Keith Pardee and an international team of collaborators, including scientists from the Wyss Institute at Harvard University, have developed a low-cost, easy-to-use diagnostic platform for detecting the Zika virus.

9 May 2016

Researchers find way to selectively deliver drugs to placenta without harming fetus

Nearly 10 percent of babies born in the United States are born premature, according to the March of Dimes. The underlying cause of many complications during pregnancy is often a poorly functioning placenta, the organ that nourishes and maintains the fetus.

9 May 2016

Blood News and Research

EvOx Therapeutics raises £10m to target new therapeutic system for untreatable diseases

Chronic use of antacid drugs may speed up aging of blood vessels

Non-invasive 3-D virtual heart assessment tool can help predict arrhythmia risk in patients

Oral regimens could offer simple solution for severe hyperglycaemia

Potential new intraocular treatment based on RAS manipulation can prevent or reverse diabetic retinopathy

Sophisticated technology helps model and simulate optimal dose for pediatric ependymoma patients

Scientists discover new genetic information about development of breast cancer

UCLA neurologist highlights steps that can help Americans reduce stroke risk

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

Digital health: putting patients at the center. An interview with Roz Davies

Videogame addiction may impact sleep habits, obesity and cardio-metabolic health among children and teens

Experimental vaccine protects healthy U.S. adults from malaria infection for more than one year

Caltech researchers discover new potential cause for Crohn's disease

CoSTREAM project aims to find common mechanisms, pathways in stroke and Alzheimer's disease

New set of practice guidelines from WMS may help in treatment, prevention of drowning

Food deprivation may help treat fatty liver disease

Research shows spleen MZ B cells produce signaling proteins involved in inflammatory responses

Controlling heart cells using a laser: an interview with Prof. Konstantin Agladze

Scientists develop low-cost, easy-to-use diagnostic platform to detect Zika virus

Researchers find way to selectively deliver drugs to placenta without harming fetus

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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