Laboratory News and Research

RSS

Fine tuning drug levels in neuroblastoma patients is effective

Monitoring and fine tuning the levels of the cancer drug topotecan in children with neuroblastoma holds promise for maximizing the drug's effectiveness while reducing its toxicity, according to investigators at St. Jude Children's Research Hospital.

16 Jun 2005

Scientists have tracked down the biological trigger that gives rise to Van Buchem disease

...a hereditary, disfiguring bone disorder that can cause blindness and deafness. The findings provide insight into long-range gene regulation and could lead to new treatments for osteoporosis and other crippling bone disorders.

16 Jun 2005

Columbia University launches multi-year campaign to support stem cell researc

Columbia University Medical Center (CUMC) has announced that it is halfway toward realizing the first phase of a multi-year campaign to build upon the university’s groundbreaking stem cell research and lead the effort to fully realize the therapeutic potential of stem cells.

16 Jun 2005

Wonder drug attacks range of cancers

A team of cancer research scientists from the Royal Marsden Hospital in London say the drug 17AAG has shown in early trials, promising signs of fighting a range of cancers.

16 Jun 2005

First human case of bird flu found in Indonesia

The World Health Organization (WHO) has reported that the first human case of bird flu has been diagnosed in Indonesia.

16 Jun 2005

USDA still not coming clean on reasons for new mad cow tests

The U.S. Agriculture Department's inspector general is still not coming clean on why new tests were ordered unexpectedly on brain tissue from a cow declared free of mad cow disease seven months ago.

16 Jun 2005

Jumping genes help detemine uniqueness of individual brains

Scientists at the Salk Institute for Biological Studies may have found one explanation for the puzzling variety in brain organization and function: mobile elements, pieces of DNA that can jump from one place in the genome to another, randomly changing the genetic information in single brain cells.

15 Jun 2005

Walking more slowly, obese individuals can burn more calories per mile and may reduce the risk of arthritis or joint injury

Leisurely walking for distance combined with low-impact cardiovascular activity appears to be the best formula for obese people seeking to get into shape and stay healthy, according to a University of Colorado at Boulder study.

15 Jun 2005

Nanotechnology used to smuggle a powerful chemotherapeutic drug inside tumor cells

University of Michigan scientists have created the nanotechnology equivalent of a Trojan horse to smuggle a powerful chemotherapeutic drug inside tumor cells - increasing the drug's cancer-killing activity and reducing its toxic side effects.

15 Jun 2005

Arteries bio-engineered from elderly cells

Researchers from Duke University's Medical Center and Pratt School of Engineering have demonstrated that they can grow new human blood vessels from cells taken from patients who especially need such assistance – older adults with cardiovascular disease.

14 Jun 2005

Holographic movies show promise for medical applications

In a small research laboratory at UT Southwestern Medical Center, a grainy, red movie of circling fighter jets emerges from a table-top black box, while nearby, a video of a rotating human heart hangs suspended in a tank of gooey gel.

14 Jun 2005

The most frequently used drugs for treating chronic insomnia have never been approved for that purpose

Vaughn McCall, M.D., M.S., professor and chairman of the Department of Psychiatry and Behavioral Medicine, told a special consensus panel at the National Institutes of Health (NIH) that he could find no evidence that randomized controlled clinical trials had ever been conducted for five of the 10 pharmaceuticals prescribed most often for chronic insomnia.

14 Jun 2005

Two common gene variations are associated with the risk for developing chronic kidney disease

Two common gene variations are associated with the risk for developing chronic kidney disease, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions. One variant increases risk and the other decreases risk with a similar effect in whites, African-Americans, diabetic and non-diabetic individuals.

14 Jun 2005

Tetanus toxin may help fight depression, anxiety, anorexia and Parkinson's

A team of researchers from the Department of Biochemistry and Molecular Biology and the Institute of Neuroscience at the Universitat Autònoma de Barcelona has discovered that tetanus toxin, which causes tetanus, could be extremely useful as a therapy against psychological disorders such as depression, anxiety and anorexia, and to slow the progress of neurodegenerative disorders such as Parkinson's disease.

14 Jun 2005

Invasive treatment including stenting may be more effective for heart attack patients who arrive late at hospital

Invasive treatment including stenting may have better outcomes than conventional treatments for heart attack patients who arrive at the hospital more than 12 hours after symptoms began, according to a study in the June 15 issue of JAMA.

14 Jun 2005

Causes, consequences and clinical implications of alcohol-related brain shrinkage

Previous studies have demonstrated that the brains of alcoholics are smaller, lighter and "shrunken" when compared to nonalcoholic brains.

14 Jun 2005

Reasons for delay in re-testing for mad cow disease still causes concern

According to the U.S. Department of Agriculture (USDA), it now appears that the animal suspected of having mad cow disease was born before the implementation of the 1997 feed ban that prohibits cattle remains in animal feed.

14 Jun 2005

US scientists find "mother of all brain stem cells"

Scientists at the University of Florida have been able grow brain cells in the laboratory.

14 Jun 2005

Anti-cancer drug may help prevent premature births

A team from University of Newcastle upon Tyne in the UK have found that the anti-cancer drug Trichostatin A (TSA), has the potential to control early labour contractions. They are optimistic the work, which is still in the early stages, will help to reduce the 70,000 premature births in the UK each year.

14 Jun 2005

Anti-cancer drug could be the first effective treatment for premature births

An anti-cancer drug could potentially be the first effective treatment for the many thousands of premature births that occur worldwide each year, scientific tests have found.

13 Jun 2005