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Use of positron emission tomography may eliminate more strenuous drug development trials with animals

A number of articles explore the use of positron emission tomography (PET) and small animal imaging—nonsurgical techniques that open the door to understanding and treating human diseases—in the April issue of the Society of Nuclear Medicine’s Journal of Nuclear Medicine.

26 Apr 2005

Fickle enzyme helps protect, but also can promote heart failure

Enzymes that make the gas nitric oxide (NO) not only protect the heart from damage due to high blood pressure or a heart attack, but also promote heart failure through overgrowth and enlargement of the muscle tissue, say animal researchers at Johns Hopkins.

26 Apr 2005

Gene therapy for Alzheimer's disease shows promise

In the first clinical trial of gene therapy for Alzheimer's disease researchers have produced preliminary evidence that gene therapy may slow the decline in mental functioning associated with Alzheimer's disease.

25 Apr 2005

H7 strain of the bird flu outbreak in North Korea contained

The recent outbreak of avian influenza in North Korea (DPRK) has been successfully contained, FAO said today, urging the country to continue surveillance on the affected farms and elsewhere to ensure that no residual infection remains.

25 Apr 2005

Important new finding about the brain and its stem cells

A family's bravery and generosity in the face of their son's death three years ago has enabled researchers to make an important new finding about the brain and its stem cells.

25 Apr 2005

Study sheds light on why normal prion proteins may experience age-related mutations in inherited diseases

A new study sheds light on why normal prion proteins may experience age-related mutations in inherited diseases. Researchers at the Case Western Reserve University School of Medicine studied a previously discovered mutation in the prion protein in members of an extended family in Indiana who inherited the prion disease Gerstmann-Straussler-Sheinker (GSS).

25 Apr 2005

As syphilis rates increase in Los Angeles County, new study suggests the disease is increasing HIV rates

The syphilis epidemic among men who have sex with men in Los Angeles County may be contributing to rates of HIV in this population, according to a new report published in the Journal of Acquired Immune Deficiency Syndrome.

23 Apr 2005

How Ebola virus infects cells - discovery

Ebola virus reproduction in laboratory-grown cells is severely hampered by enzyme-inhibiting chemicals, and these chemicals deserve further study as possible treatments for Ebola virus infections in humans, report scientists supported in part by the National Institute of Allergy and Infectious Diseases (NIAID).

23 Apr 2005

Ensuring patient safety at fertility clinics

In the years since the birth of the first ‘test-tube’ baby in 1978, in-vitro fertilisation (IVF) has grown to become an accepted mainstream medical technique, with more than 25,000 treatments carried out every year.

23 Apr 2005

UK plan for influenza pandemic

The HPA Influenza Pandemic Contingency Plan outlines the Health Protection Agency’s plan for responding to an influenza pandemic. It replaces the Public Health Laboratory Service Pandemic Influenza Plan of July 2001.

23 Apr 2005

Canadian Diabetes Association, UBC partner on funding for childhood diabetes research

A new partnership announced by the Canadian Diabetes Association and the University of British Columbia (UBC) will help fund research in childhood diabetes. Not only will this research further investigate type 1 diabetes, it will also explore the areas of type 2 diabetes and obesity in children, a problem of growing concern and proportions.

23 Apr 2005

Scientists have, for the first time, induced a state of reversible metabolic hibernation in mice

Scientists at Fred Hutchinson Cancer Research Center have, for the first time, induced a state of reversible metabolic hibernation in mice. This achievement, the first demonstration of "hibernation on demand" in a mammal, ultimately could lead to new ways to treat cancer and prevent injury and death from insufficient blood supply to organs and tissues.

23 Apr 2005

Using light under your skin

You have a tiny wound on your hand that doesn’t heal, a bad burn on your chest – or an injured retina. Your doctor cannot tell how serious the injuries are below the surface. He needs tissue samples. That means using a scalpel, which again equals pain, perhaps even a risk. Soon there may be hope for an improved and totally harmless method to peer under the surface of the skin: light.

23 Apr 2005

Could diabetes drug prevent cancer?

A well known drug which is commonly used to treat Type 2 diabetes may prevent cancer tumours, according to researchers at the University of Dundee.

23 Apr 2005

Rare surgery performed to remove pancreas, prevent diabetes and ease pain of chronic pancreatitis

In a 12-hour, dual-stage surgery known to be performed at only two other centers in the U.S., doctors at the University of Alabama at Birmingham (UAB) on Tuesday returned a patient's own insulin-producing cells to him after surgically removing his pancreas to eliminate constant, severe pain from chronic pancreatitis.

22 Apr 2005

Almost all killer flu bug kits destroyed

99 percent of the kits containing a killer flu bug that mistakenly ended up in thousands of laboratories around the world, sparking fears of a pandemic, have been destroyed, according to top U.S. health official Dr. Julie Gerberding, director of the Centers for Disease Control and Prevention (CDC).

22 Apr 2005

Golfers "yips" possibly a movement disorder

Researchers have found that a not uncommon condition among some golfers, Yips, a term used to denote a strong tendency to flinch or twitch during putting, may be a task-specific movement disorder akin to writer's cramp and musician's cramp.

21 Apr 2005

Meat Institute defends hot dogs in recent pancreatic cancer study

In response to the report released today at the American Association for Cancer Research in Anaheim, California, attempting to link processed meats to pancreatic cancer, James L. Hodges, President of the American Meat Institute Foundation made the following comment:

20 Apr 2005

RNA interference permanently silences key breast cancer gene

In laboratory mouse experiments, researchers at The University of Texas M. D. Anderson Cancer Center have developed a way to use RNA interference (RNAi) so that it permanently hampers breast cancer development. The technique permanently silences activated STAT3, a crucial gene found in some human breast tumors, thus reducing the cancer's ability to become invasive.

20 Apr 2005

Green tea appears to prevent cancer in men

After a year's oral administration of green tea catechins (GTCs), only one man in a group of 32 at high risk for prostate cancer developed the disease, compared to nine out of 30 in a control, according to a team of Italian researchers from the University of Parma and University of Modena and Reggio Emilia led by Saverio Bettuzzi, Ph.D.

20 Apr 2005