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Two established atrial fibrillation ablation techniques show similar effects, safety outcomes

Two established techniques for correcting the root cause of the heart rhythm disorder atrial fibrillation show similar effects and safety outcomes, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

5 Apr 2016

New implantable medical device fails to reduce rates of heart failure-related hospitalization

A new implantable medical device intended to help patients with heart failure by stimulating the vagus nerve did not significantly reduce rates of heart failure-related hospitalization or death from any cause in a study presented at the American College of Cardiology's 65th Annual Scientific Session.

5 Apr 2016

Adding liraglutide to diet and exercise plan may help people lose weight, reduce diabetes risk

For people with prediabetes who are overweight or obese, adding 3.0 mg of liraglutide for three years to a diet and exercise plan may lead to major health improvements, new industry-sponsored research suggests. The results will be presented Monday, April 4, at ENDO 2016, the annual meeting of the Endocrine Society, in Boston.

5 Apr 2016

Investigational stem cell therapy improves outcomes in patients with severe heart failure

An investigational stem cell therapy derived from patients' own blood marrow significantly improved outcomes in patients with severe heart failure, according to a study from the Cedars-Sinai Heart Institute.

5 Apr 2016

Tests used for diagnosing heart disease appear to function differently for women and men

Tests used to diagnose and assess the severity of coronary artery disease appear to function differently for women and men who have stable symptoms, according to researchers from Duke Clinical Research Institute.

5 Apr 2016

Edema Guard Monitor appears to reduce heart failure-related hospitalizations by more than half

In patients with heart failure, use of an investigational device that monitors the accumulation of fluid in the lungs appeared to cut heart failure-related hospitalizations by more than half, meeting the study's primary endpoint, and reduced deaths from any cause by 39 percent per year compared with standard assessment and treatment, researchers reported at the American College of Cardiology's 65th Annual Scientific Session.

5 Apr 2016

Inhalable form of Ambrisentan drug could offer faster-acting treatment option for pulmonary edema

In a new study, researchers show an aerosolized, inhalable form of the drug Ambrisentan could offer a faster-acting treatment option for pulmonary edema, a life-threatening condition in which fluid accumulates in the lungs. Pulmonary edema is a significant risk for anyone spending time at high altitudes, and also affects people with chronic conditions including congestive heart failure and sickle cell anemia.

5 Apr 2016

Blocking blood supply of small cell lung cancer tumors may help delay cancer relapse

A study by researchers at Marshall University Joan C. Edwards School of Medicine has found that blocking the blood supply of small cell lung cancer tumors may help reduce their growth and delay the regrowth process after treatment. Small cell lung cancer is considered the most lethal of all lung cancers.

5 Apr 2016

Study evaluates long-term outcomes of TAVR with SAPIEN 3 in intermediate-risk patients

To account for baseline differences, TAVR patients were compared by a propensity score analysis with patients randomized to receive surgical intervention in a precursor study, PARTNER 2A. Propensity scoring analysis is a statistical technique used to reduce bias from potential confounding variables, which in this case was used to identify surgical patients from a previous study who would be comparable to TAVR patients in this study.

4 Apr 2016

Magnesium could be safe, cost-effective therapeutic intervention for genetic coagulation disorder

An international team of scientists was able to demonstrate in mouse and patient studies, how magnesium affects the production of blood platelets and that the TRPM7 channel function plays a key role in this process. Scientists of the Rudolf Virchow Center and the Hospital of the University of Würzburg were primarily involved in this study. Their results were published in the current journal "Nature Communications".

4 Apr 2016

Researchers find pathway to prevent emergence of zoonosis into human population

The parasite responsible for a form of malaria now spreading from macaques to humans in South Asia could evolve to infect humans more efficiently, a step towards enhanced transmission between humans, according to a new study from Harvard T.H. Chan School of Public Health. The researchers say that defining the means by which the Plasmodium knowlesi parasite invades red blood cells could lead to interventions to prevent the emergence of the zoonosis into the human population.

4 Apr 2016

Ischemic postconditioning for STEMI patients shows no clinical outcomes

A large randomized controlled trial of ischemic postconditioning in patients who had experienced the deadliest form of heart attack—ST-segment elevation myocardial infarction (STEMI)—failed to show that this procedure significantly reduces death from any cause or hospitalization for heart failure, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Prostatic artery embolization improves sleep, quality of life for men with enlarged prostates

An innovative interventional radiology treatment for men with enlarged prostates decreases the number of times they wake to urinate in the night, according to research presented at the Society of Interventional Radiology's 2016 Annual Scientific Meeting. Researchers said the majority of men with enlarged prostates and lower urinary tract symptoms reported better sleep that resulted in an improved quality of life after they underwent a treatment called prostatic artery embolization (PAE).

4 Apr 2016

Society of Interventional Radiology honors outstanding achievers with annual awards

Renan Uflacker, M.D., FSIR, was honored posthumously on April 3 with the Society of Interventional Radiology Foundation Leaders in Innovation Award. The award was announced during the Society of Interventional Radiology's Annual Scientific Meeting in Vancouver, British Columbia.

4 Apr 2016

Evolocumab could be more effective than ezetimibe in lowering cholesterol in statin-intolerant patients

In the first major trial of its kind, Cleveland Clinic researchers used a blinded rechallenge with atorvastatin or placebo to objectively confirm the presence of muscle-related symptoms in patients with a history of intolerance to multiple statins and found that evolocumab (a PCSK9 inhibitor) was a more effective option to lower cholesterol than ezetimibe in these patients.

4 Apr 2016

MedUni Vienna researchers identify reason for chemoresistance in small cell lung cancer

Small cell lung cancer is not usually detected until it is at an advanced stage, when metastases have already formed. Chemotherapy is very effective initially but, within a year, cancer recurs and this time does not respond to a course of chemotherapy. The research group headed by Gerhard Hamilton, University Department of Surgery at MedUni Vienna, has now managed to identify the reason for this chemoresistance.

4 Apr 2016

Intravenous beta blockers offer no clinical benefit to patients with STEMI

Giving intravenous beta blockers before performing a coronary angioplasty in patients who had experienced the deadliest form of heart attack—ST-segment elevation myocardial infarction (STEMI)—was safe but did not reduce heart attack severity or improve blood flow from the heart's main pumping chamber, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Bariatric arterial embolization safe, effective in sustaining weight loss in severely obese people

Findings from the early phase of a clinical trial led by Johns Hopkins investigators indicates that a new, minimally invasive weight loss treatment known as bariatric arterial embolization is safe and effective in sustaining weight loss in severely obese people.

4 Apr 2016

Combining aromatase inhibitors with growth hormone may help short adolescent boys grow taller

Aromatase inhibitors, when used for up to three years in combination with growth hormone, may effectively and safely help very short adolescent boys grow taller, new research suggests. The study results will be presented Sunday, April 3, at ENDO 2016, the annual meeting of the Endocrine Society in Boston.

4 Apr 2016

Oral Salmonella-based vaccine could prevent Type 1 diabetes

A combined vaccine therapy including live Salmonella is a safe and effective way to prevent diabetes in mice and may point to future human therapies, a new study finds. The results will be on Sunday, April 3, at ENDO 2016, the annual meeting of the Endocrine Society, in Boston.

4 Apr 2016

Blood News and Research

Two established atrial fibrillation ablation techniques show similar effects, safety outcomes

New implantable medical device fails to reduce rates of heart failure-related hospitalization

Adding liraglutide to diet and exercise plan may help people lose weight, reduce diabetes risk

Investigational stem cell therapy improves outcomes in patients with severe heart failure

Tests used for diagnosing heart disease appear to function differently for women and men

Edema Guard Monitor appears to reduce heart failure-related hospitalizations by more than half

Inhalable form of Ambrisentan drug could offer faster-acting treatment option for pulmonary edema

Blocking blood supply of small cell lung cancer tumors may help delay cancer relapse

Study evaluates long-term outcomes of TAVR with SAPIEN 3 in intermediate-risk patients

Magnesium could be safe, cost-effective therapeutic intervention for genetic coagulation disorder

Researchers find pathway to prevent emergence of zoonosis into human population

Ischemic postconditioning for STEMI patients shows no clinical outcomes

Prostatic artery embolization improves sleep, quality of life for men with enlarged prostates

Society of Interventional Radiology honors outstanding achievers with annual awards

Evolocumab could be more effective than ezetimibe in lowering cholesterol in statin-intolerant patients

MedUni Vienna researchers identify reason for chemoresistance in small cell lung cancer

Intravenous beta blockers offer no clinical benefit to patients with STEMI

Bariatric arterial embolization safe, effective in sustaining weight loss in severely obese people

Combining aromatase inhibitors with growth hormone may help short adolescent boys grow taller

Oral Salmonella-based vaccine could prevent Type 1 diabetes

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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