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New ideas for creating a new generation of oral medications to treat infertility

Researchers now have a much better picture of how follicle-stimulating hormone (FSH), one of the most frequently used fertility drugs, works, and with it new ideas for creating a new generation of oral medications to treat infertility.

20 Jan 2005

Sildenafil restores cognitive function in rats after liver failure

A study involving rats reveals the mechanism responsible for learning impairment due to liver failure and shows that sildenafil restores cognitive function.

19 Jan 2005

Clopidogrel (Plavix®) responses appear normal in largest data set

Although individual patients respond differently to treatment with the anti-platelet medication clopidogrel (brand name Plavix®), those variations appear normal and may not indicate important differences in the effectiveness of treatment, according to a new study (PDF file) in the Jan. 18, 2005 issue of the Journal of the American College of Cardiology.

19 Jan 2005

Cellular fuel gauge could hold clue to diabetes

A molecule in the body could hold the key to explaining why people who exercise regularly are less likely to have illnesses such as type 2 diabetes.

19 Jan 2005

Survey finds that many recover from alcoholism

More than one-third (35.9 percent) of U.S. adults with alcohol dependence (alcoholism) that began more than one year ago are now in full recovery, according to an article in the current issue of Addiction.

19 Jan 2005

Scientists identify fat gene

UCLA/VA scientists have identified a new gene that controls how the body produces and uses fat. Called lipin, the gene may provide a new target for therapies to control obesity, diabetes and other weight-related disorders. The first issue of the new journal Cell Metabolism publishes the findings in its January 2005 edition.

19 Jan 2005

Screening tests find colorectal cancer in its earliest stages when it can be treated more successfully

Colorectal cancer (CRC) is second only to lung cancer as the leading cause of cancer-related death in the United States. In 2004, it’s estimated that CRC caused nearly 57,000 deaths.

18 Jan 2005

Home HIV-AIDS test could be a reality within two years

A portable device similar to a home pregnancy test that can quickly detect the presence of infectious diseases, including HIV-AIDS and measles as well as biological agents such as Ricin and anthrax, is the goal of a new joint research project

17 Jan 2005

Damp and mould in homes causes asthma

Researchers at the University of Birmingham's Institute for Occupational and Environmental Medicine are citing damp and mould in homes as a cause of asthma. The study is published in the Environmental Health Perspectives journal and links the University of Birmingham with the University of Helsinki, Finland and the Diwan College, Taiwan.

17 Jan 2005

Molecular pathway turns a juvenile heart into an adult heart

Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered the molecular sequence of events in mice that turn a juvenile heart into an adult heart capable of responding to increased workloads.

17 Jan 2005

Missing sequence of the human Y chromosome may contain genes controlling stature and tumor development

Scientists have reported in the journal Genome Research that they have successfully cloned and characterized a previously intractable DNA sequence: a 554-kilobase-pair genomic segment near the centromere of the human Y chromosome. This sequence contains eight putatively active genes that could be implicated in sex-associated height differences and gonadal tumor development.

16 Jan 2005

Virtual pain relief for children

Children who have the distraction of a virtual reality game while undergoing post-operative physiotherapy, report a significant decrease in their experience of pain, new research at the University of South Australia has found.

12 Jan 2005

Research breakthrough in treatment of TB and MDR-TB

FASgen Inc.'s compound, FAS20013, has emerged from an intense multi-year program of pre-clinical studies that clearly validate its potential as an ideal new drug for the treatment of tuberculosis and MDR-TB, the disease caused by organisms that are resistant to the drugs now commonly used to treat TB. Initial clinical trials in both TB and MDR-TB are scheduled for later this year.

12 Jan 2005

Screening for malaria necessary for U.S. soldiers returning from Afghanistan

Nearly 40 U.S. Army Rangers returning from Afghanistan in 2002 may have contracted malaria because of inadequate use of preventive measures, according to a study in the January 12 issue of JAMA.

12 Jan 2005

Infants have much to say if adults will only listen

A baby's first sounds, other than crying, may baffle parents. Is that soft "coo" the sound of contentment? Boredom? Nothing more than a reflex?

12 Jan 2005

Molecular Devices introduces fatty acid uptake assay to target metabolic diseases

Molecular Devices Corporation announced the launch of its QBT Fatty Acid Uptake Assay Kit, the first assay kit that addresses the need for a single-step, homogenous in vitro assay for fatty acid uptake for use in high- throughput screening and metabolic disease research.

12 Jan 2005

Lack of sleep could make you fat

Lack of sleep could make you fat. In an editorial published in the Jan. 10 issue of the Archives of Internal Medicine, two Northwestern University researchers stress the need to better understand the growing epidemic of obesity in the United States by studying how loss of sleep alters the complex metabolic pathways that control appetite, food intake and energy expenditure.

10 Jan 2005

New portable infectious disease detector

A portable device similar to today's home pregnancy tests that can quickly detect the presence of infectious diseases, including HIV-AIDS and measles, as well as biological agents such as ricin and anthrax, is the object of a new joint university/industry research project.

10 Jan 2005

Scientists identify a protein that regulates alcohol-withdrawal seizures

Seizures are the most life-threatening, as well as disconcerting, symptoms of withdrawal in people who are alcoholics and who abruptly stop drinking. Heavy consumption of alcohol, or ethanol, the substance in beer, wine and liquor that is addictive, leads to changes in the brain.

10 Jan 2005

Why the Mediterranean diet appers to protect against breast cancer

U.S. researchers have uncovered reasons why the Mediterranean diet, with its high intake of oleic acid-rich olive oil, seems to protect against breast cancer. They have also found evidence that oleic acid may have a future role in treatment. The findings are reported (Monday 10 January) in Annals of Oncology.

9 Jan 2005