Laboratory News and Research

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Nicotine absorption is much lower from second-hand vaping than from second-hand smoking

Children exposed to vaping indoors absorb less than one seventh the amount of nicotine as children who are exposed to indoor smoking, but more than those exposed to neither, according to a new study led by UCL researchers.

11 Jul 2024

New study reveals the genetic cause of Parkinson's disease

According to Science Alert, neuroscientists from Johns Hopkins University have recently discovered a new treatment for Parkinson's disease using an FDA-approved cancer drug.

11 Jul 2024

CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma

CAR-T cell therapy, which targets a specific protein on the surface of cancer cells, causes tumors to shrink or disappear in about half of patients with large B-cell lymphoma who haven't experienced improvement with chemotherapy treatments.

11 Jul 2024

Novel Co-STAR cells show promise in targeting and eradicating cancer

Using genetic engineering techniques, investigators at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center, the Lustgarten Laboratory and Bloomberg~Kimmel Institute for Cancer Immunotherapy have designed a novel type of cell to recognize and fight cancer.

11 Jul 2024

Group of small molecules exclusive to liver tumors could be key to developing cancer vaccines

A study led by the Hospital del Mar Research Institute, with Cima University of Navarra and Pompeu Fabra University, has identified a group of small molecules exclusive to liver tumors that could be key to developing cancer vaccines.

11 Jul 2024

Finland is offering farmworkers bird flu shots. Some experts say the US should, too.

As bird flu spreads among dairy cattle in the U.S., veterinarians and researchers have taken note of Finland's move to vaccinate farmworkers at risk of infection. They wonder why their government doesn't do the same.

11 Jul 2024

Researchers identify shared molecular mechanism in cancer and pregnancy that suppresses immune system

Researchers elucidated the shared immune tolerance mechanisms in cancer and pregnancy, focusing on the role of an immune checkpoint protein as an onco-fetal immune tolerance checkpoint.

11 Jul 2024

Advanced imaging reveals hidden vision loss in AMD

New research by the University Hospital Bonn (UKB) in cooperation with the University of Bonn has shown for the first time that certain early changes in patients with age-related macular degeneration (AMD) can lead to a measurable local loss of vision. This discovery could help to improve the treatment and monitoring of this eye disease in older patients, which otherwise slowly leads to central blindness, and to test new therapies.

11 Jul 2024

Existing drug shows promise for treating common liver disease

The University of Barcelona has led a study that suggests using the drug known as pemafibrate to treat liver disease associated with metabolic disorders, the most common liver pathology in the world, which affects one in four people. The drug has long been marketed in Japan for another use: improving blood lipid levels in patients with hyperlipidaemia, a common condition in diabetics. Now, however, it could help address this serious liver disease, which still has no specific treatment.

11 Jul 2024

Repurposing pemafibrate to treat liver disease associated with metabolic disorders

10 Jul 2024

Cryo-EM reveals structural dynamics of RNAP-DNA interactions during transcription initiation

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one exposed DNA strand can be copied into a complementary RNA strand.

10 Jul 2024

Exploring the benefits of miniaturizing NGS library preparation

In this interview, Huw Rees, a field application scientist at SPT Labtech, discusses the benefits of miniaturization in NGS library preparation and how using mosquito® can give you more value for your money.

From SPT Labtech 10 Jul 2024

KNAUER’s top-selling HPLC systems now ACT Ecolabel certified

The environmental impact of KNAUER's top-selling HPLC systems has now been evaluated by My Green Lab with the assignment of its ACT Ecolabel.

10 Jul 2024

Tirzepatide outperforms semaglutide in weight loss for overweight and obese adults

Tirzepatide leads to significantly greater weight loss than semaglutide in overweight or obese adults, with no significant difference in gastrointestinal adverse effects.

10 Jul 2024

Novel device uses a simple blood test to detect early stage lung cancer

University of Queensland researchers have designed a device that uses a simple blood test to detect early stage lung cancer.

10 Jul 2024

Bovine H5N1 flu virus in cow milk poses significant health risks, study shows

Study characterizes the pathogenicity and transmission dynamics of the H5N1 influenza virus in bovine milk, highlighting significant public health risks and potential mammalian transmission.

10 Jul 2024

Pregnancy loss risk heightened by family history of endocrine diseases

Women who have close family members with endocrine diseases, including type 2 diabetes, thyroid diseases and polycystic ovary syndrome (PCOS), are at higher risk of pregnancy loss, a new study has found.

9 Jul 2024

Study examines the frequency and preventability of adverse drug events in outpatient settings

Rachel L. Wasserman, PharmD, of the Department of General Internal Medicine at Brigham and Women's Hospital, is the lead author and David W. Bates, MD, medical director of Clinical and Quality Analysis for Mass General Brigham and Co-Director of the Center for Artificial Intelligence and BioInformatics for Mass General Brigham, is the senior author of a new study published in BMJ Quality & Safety, "Frequency and preventability of adverse drug events in the outpatient setting."

9 Jul 2024

New platform developed to probe the function of genes involved in metabolism

A multidisciplinary research team has developed a discovery platform to probe the function of genes involved in metabolism - the sum of all life-sustaining chemical reactions.

9 Jul 2024

Cow's milk may spread H5N1 flu, but airborne transmission is limited

While H5N1 avian influenza virus taken from infected cow's milk makes mice and ferrets sick when dripped into their noses, airborne transmission of the virus between ferrets - a common model for human transmission - appears to be limited.

9 Jul 2024

Laboratory News and Research

Nicotine absorption is much lower from second-hand vaping than from second-hand smoking

New study reveals the genetic cause of Parkinson's disease

CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma

Novel Co-STAR cells show promise in targeting and eradicating cancer

Group of small molecules exclusive to liver tumors could be key to developing cancer vaccines

Finland is offering farmworkers bird flu shots. Some experts say the US should, too.

Researchers identify shared molecular mechanism in cancer and pregnancy that suppresses immune system

Advanced imaging reveals hidden vision loss in AMD

Existing drug shows promise for treating common liver disease

Repurposing pemafibrate to treat liver disease associated with metabolic disorders

Cryo-EM reveals structural dynamics of RNAP-DNA interactions during transcription initiation

Exploring the benefits of miniaturizing NGS library preparation

KNAUER’s top-selling HPLC systems now ACT Ecolabel certified

Tirzepatide outperforms semaglutide in weight loss for overweight and obese adults

Novel device uses a simple blood test to detect early stage lung cancer

Bovine H5N1 flu virus in cow milk poses significant health risks, study shows

Pregnancy loss risk heightened by family history of endocrine diseases

Study examines the frequency and preventability of adverse drug events in outpatient settings

New platform developed to probe the function of genes involved in metabolism

Cow's milk may spread H5N1 flu, but airborne transmission is limited

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