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CHLA cardiologists perform rare fetal cardiac intervention procedure

Last August, when Children's Hospital Los Angeles cardiologists confirmed that the heart of a 27-week-old fetus suffered from a critical cardiac condition that prevented blood returning from the fetus's lungs from circulating back into the body, they told the parents that their child faced certain open-heart surgery after birth. Even worse, babies born with this very rare condition—hypoplastic left heart syndrome (HLHS) with restrictive atrial septum—have a 50 percent neonatal mortality rate.

27 Feb 2016

Discovery highlights need to improve patient education about genomics

An overwhelming majority of people with incurable cancer want to hear findings from DNA sequencing of their own tumors and normal cells, and to learn how those results may affect their health and treatment options, Dana Farber Cancer Institute scientists report.

27 Feb 2016

PCSK9-inhibitor drugs: A game-changer for individuals with extremely high cholesterol levels

A 59-year-old heart patient with dangerously high levels of cholesterol that could not be adequately reduced by statin drugs now has near-normal cholesterol levels, thanks to a new class of drugs that grew out of work done by UT Southwestern Medical Center researchers.

27 Feb 2016

Changes in use of anemia drugs affects risk of death or cardiovascular events in dialysis patients

A new study examines whether recent changes in the use of anemia drugs for patients on dialysis have contributed to changes in rates of death or cardiovascular events. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology, indicate that these risks appear to be decreasing for patients on dialysis as well as for older adults (Medicare beneficiaries) who are not on dialysis.

27 Feb 2016

Vanderbilt to lead Direct Volunteers Pilot Studies under Precision Medicine Initiative Cohort Program

Federal officials with the White House and National Institutes of Health announced today that Vanderbilt University Medical Center will lead the Direct Volunteers Pilot Studies under the first grant to be awarded in the federal Precision Medicine Initiative Cohort Program.

27 Feb 2016

Research unveils standard front-line treatment for advanced ovarian cancer

Research led by a Dignity Health St. Joseph's Hospital and Medical Center physician on ovarian cancer was published in the Feb. 24, 2016 issue of New England Journal of Medicine. The research was directed by Bradley J. Monk, M.D. and researchers at 12 other medical facilities around the nation.

27 Feb 2016

WRAIR researchers publish results from Plasmodium vivax malaria vaccine study

Walter Reed Army Institute of Research researchers recently published the results of testing a Plasmodium vivax malaria vaccine candidate in a human challenge model.

27 Feb 2016

Muscle-sparing abdominal flaps can reduce complications in women undergoing breast reconstruction

In women undergoing breast reconstruction using their own (autologous) tissue, newer "muscle-sparing" abdominal flaps can reduce complications while improving some aspects of quality of life, reports a study in the March issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

27 Feb 2016

Understanding range of neurological disease linked with Zika virus is urgent priority, warn researchers

Understanding the scale and range of neurological disease associated with Zika virus infection is an urgent priority, warn researchers from the University of Liverpool's Institute of Infection and Global Health.

27 Feb 2016

Insecticide-treated nets help prevent spread of malaria

Insecticide-treated nets may still help prevent malaria despite mosquitoes developing resistance, according to a new study published in Parasites & Vectors.

27 Feb 2016

Researchers find way to boost the body's natural cancer-killing cells

The immune cells, called natural killer cells, hunt and destroy foreign cells in the body, including cancer cells that spread and form tumours.

27 Feb 2016

Researchers conduct study of Ebola survivors in Sierra Leone

Researchers from the University's Institute of Translational Medicine have conducted a study of Ebola survivors to describe the medical problems they continue to have after recovering from the acute disease.

27 Feb 2016

Brains have different traits that affect anatomical and cognitive factors

Everyone has a different mixture of personality traits: some are outgoing, some are tough and some are anxious. A new study suggests that brains also have different traits that affect both anatomical and cognitive factors, such as intelligence and memory.

27 Feb 2016

Penn State researchers develop self-powered enzyme pumps

A new way to use the chemical reactions of certain enzymes to trigger self-powered mechanical movement has been developed by a team of researchers at Penn State University and the University of Pittsburgh. A paper describing the team's research, titled "Convective flow reversal in self-powered enzyme micropumps," is published this week in the journal Proceedings of the National Academy of Sciences.

27 Feb 2016

TTR protein causes autoimmune reaction in joints of juvenile idiopathic arthritis patients

Juvenile idiopathic arthritis, or JIA, is the most common form of childhood arthritis. It appears to be an autoimmune disease, caused by antibodies attacking certain proteins in a person's own tissue. But no "autoantigens" -- the proteins triggering an immune attack -- have been linked to JIA.

27 Feb 2016

New drug shows promise against Huntington's disease

A drug that would be the first to target the cause of Huntington's disease (HD) is effective and safe when tested in mice and monkeys, according to data released today that will be presented at the American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.

27 Feb 2016

Novartis announces FDA approval of Afinitor for progressive, nonfunctional neuroendocrine tumors of GI

Novartis today announced that the United States Food and Drug Administration approved Afinitor (everolimus) tablets for the treatment of adult patients with progressive, well-differentiated, nonfunctional neuroendocrine tumors (NET) of gastrointestinal (GI) or lung origin that are unresectable, locally advanced or metastatic.

26 Feb 2016

Homeless adults have more geriatric conditions than those living in homes

Homeless people in their fifties have more geriatric conditions than those living in homes who are decades older, according to researchers at UC San Francisco who are following 350 people who are homeless and aged 50 and over, in Oakland.

26 Feb 2016

EMA grants Orphan Drug Designation to venetoclax for treatment of acute myeloid leukemia

AbbVie, a global biopharmaceutical company, today announced the European Medicines Agency has granted Orphan Drug Designation to venetoclax, an investigational, oral B-cell lymphoma-2 (BCL-2) inhibitor, for the treatment of acute myeloid leukemia (AML).

26 Feb 2016

Out-of-towners using marijuana in Colorado end up in emergency room

Out-of-towners using marijuana in Colorado -- which has legally allowed sales of the drug in retail dispensaries since 2014 -- are ending up in the emergency room at an increasing rate, reports a new study from Northwestern Medicine and the University of Colorado School of Medicine.

26 Feb 2016

Blood News and Research

CHLA cardiologists perform rare fetal cardiac intervention procedure

Discovery highlights need to improve patient education about genomics

PCSK9-inhibitor drugs: A game-changer for individuals with extremely high cholesterol levels

Changes in use of anemia drugs affects risk of death or cardiovascular events in dialysis patients

Vanderbilt to lead Direct Volunteers Pilot Studies under Precision Medicine Initiative Cohort Program

Research unveils standard front-line treatment for advanced ovarian cancer

WRAIR researchers publish results from Plasmodium vivax malaria vaccine study

Muscle-sparing abdominal flaps can reduce complications in women undergoing breast reconstruction

Understanding range of neurological disease linked with Zika virus is urgent priority, warn researchers

Insecticide-treated nets help prevent spread of malaria

Researchers find way to boost the body's natural cancer-killing cells

Researchers conduct study of Ebola survivors in Sierra Leone

Brains have different traits that affect anatomical and cognitive factors

Penn State researchers develop self-powered enzyme pumps

TTR protein causes autoimmune reaction in joints of juvenile idiopathic arthritis patients

New drug shows promise against Huntington's disease

Novartis announces FDA approval of Afinitor for progressive, nonfunctional neuroendocrine tumors of GI

Homeless adults have more geriatric conditions than those living in homes

EMA grants Orphan Drug Designation to venetoclax for treatment of acute myeloid leukemia

Out-of-towners using marijuana in Colorado end up in emergency room

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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