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EMA grants Orphan Drug Designation to venetoclax for treatment of acute myeloid leukemia

AbbVie, a global biopharmaceutical company, today announced the European Medicines Agency has granted Orphan Drug Designation to venetoclax, an investigational, oral B-cell lymphoma-2 (BCL-2) inhibitor, for the treatment of acute myeloid leukemia (AML).

26 Feb 2016

Out-of-towners using marijuana in Colorado end up in emergency room

Out-of-towners using marijuana in Colorado -- which has legally allowed sales of the drug in retail dispensaries since 2014 -- are ending up in the emergency room at an increasing rate, reports a new study from Northwestern Medicine and the University of Colorado School of Medicine.

26 Feb 2016

Kansas State researchers develop 3-D printed device that quickly detect anemia from blood

Identifying a blood disorder may be as easy as running a blood sample from a finger prick under a smartphone. That is the concept behind a new biomedical device being developed by Kansas State University researchers.

26 Feb 2016

Low-sodium intake has little impact on bone health in postmenopausal women

A low-salt diet does not necessarily translate to stronger bones in postmenopausal women, physician-scientists report.

26 Feb 2016

Digital health: the future for medicine?

"The best way to predict the future is to invent it," these were the words of Alan Kay quoted by Dr Euan Ashley at the Recent Developments in Digital Health 2016 event at the Royal Society of Medicine. No one exemplified this inspirational message further than Professor Tony Young, National Clinical Director for Innovation, NHS England.

26 Feb 2016

NUS scientists formulate recipe for making healthier bread

A team of food scientists from the National University of Singapore has successfully formulated a recipe for making healthier bread by adding a natural plant pigment, called anthocyanin, extracted from black rice. This new bread option gets digested at a slower rate - hence improving blood glucose control - and is high in antioxidants, among other health benefits.

26 Feb 2016

Medical scientists examine potential new tool for helping prevent stroke, heart attack

Medical scientists just vetted a potentially powerful new tool for helping prevent stroke and heart attack. In a study recently published in the New England Journal of Medicine, researchers show that a drug reduced the risk of stroke or heart attack by almost a quarter in patients who had previously suffered a stroke or mini-stroke.

26 Feb 2016

Ohio State study evaluates trans-catheter interatrial shunt device for diastolic heart failure

For the first time in the U.S., a clinical trial is underway that's evaluating a device designed to treat diastolic heart failure. The first patient enrolled in the randomized, blinded study is being treated at The Ohio State University Wexner Medical Center.

26 Feb 2016

Acute mesenteric ischemia can be treated with balloon angioplasty

Acute mesenteric ischemia (AMI) can be successfully treated with endovascular therapy such as balloon angioplasty, according to research from the University of Eastern Finland. The study also found that AMI is a more common cause of abdominal pain among the elderly than generally thought; however, it is difficult to diagnose before bowel damage develops.

26 Feb 2016

Neurosurgeons use laser probe to deliver chemotherapy drugs to patients with glioblastoma

Using a laser probe, neurosurgeons at Washington University School of Medicine in St. Louis have opened the brain's protective cover, enabling them to deliver chemotherapy drugs to patients with a form of deadly brain cancer.

26 Feb 2016

New Notre Dame research may lead to a therapy for Niemann-Pick Type C disease

Niemann-Pick Type C (NPC) disease is a rare, fatal neurodegenerative disease for which there is currently no cure. NPC primarily strikes children before and during adolescence and affects one in every 150,000 children. The disease causes cholesterol and other lipids to build up in the body's cells, which results in symptoms such as delayed motor development, deterioration of memory and balance, and seizures.

26 Feb 2016

Antidepressant paroxetine suppresses inflammation in people with HIV-related cognitive impairment

In a small, placebo-controlled clinical trial, Johns Hopkins physicians report that the antidepressant paroxetine modestly improves decision-making and reaction time, and suppresses inflammation in people with HIV-associated cognitive impairment. The researchers say they believe this is the first time that a SSRI (selective serotonin reuptake inhibitor) has been shown to improve key measures of cognition in people with HIV in a controlled study.

26 Feb 2016

Allergan receives FDA approval to market ACZONE (dapsone) Gel, 7.5% for acne treatment

Allergan plc, a leading global pharmaceutical company, today announced that the Company has received approval from the U.S. Food and Drug Administration to market ACZONE (dapsone) Gel, 7.5%, a new prescription topical treatment for acne in patients 12 years of age and older.

26 Feb 2016

China Biologic's total sales increase by 22.6% in RMB terms to $68.3 million in Q4 2015

China Biologic Products, Inc., a leading fully integrated plasma-based biopharmaceutical company in China, today announced its financial results for the fourth quarter and fiscal year of 2015.

26 Feb 2016

Baxalta seeks FDA approval for ADYNOVATE to treat children with hemophilia A and for use in surgical settings

Baxalta Incorporated, a global biopharmaceutical leader dedicated to delivering transformative therapies to patients with orphan diseases and underserved conditions, announced today that it has submitted supplemental Biologics License Applications (sBLAs) to the U.S. Food and Drug Administration seeking approval for the use of ADYNOVATE [Antihemophilic Factor (Recombinant), PEGylated] to treat children under the age of 12 with hemophilia A and for use in surgical settings.

26 Feb 2016

Immune-suppressing drug can improve cognitive ability of patients with schizophrenia

A recent study of a handful of patients supports mounting evidence that targeted suppression of inflammation packaged with standard therapy can improve the cognitive ability of patients with schizophrenia, physician-scientists report.

25 Feb 2016

Insulet partners with Mode AGC to develop OmniPod Artificial Pancreas system

Insulet Corporation, the leader in tubeless insulin pump technology with its OmniPod Insulin Management System (OmniPod System), today announced a license agreement and partnership with Mode AGC (Automated Glucose Control LLC), to develop and incorporate the advanced artificial pancreas algorithm created by renowned researchers Francis Doyle PhD, Eyal Dassau PhD, and Howard Zisser MD.

25 Feb 2016

Rigel begins fostamatinib Phase 2 trial for treatment of patients with autoimmune hemolytic anemia

Rigel Pharmaceuticals Inc. today announced that it has initiated a Phase 2 clinical trial to evaluate fostamatinib, its oral SYK inhibitor, as a potential treatment for autoimmune hemolytic anemia (AIHA).

25 Feb 2016

Moffitt researchers develop novel therapeutic strategy to keep resistant cells in check

Despite numerous advances in oncology since the War on Cancer began, many patients develop resistance to standard therapies and eventually relapse. Moffitt Cancer Center researchers hope to improve treatment outcomes with development of a novel therapeutic strategy, called adaptive therapy, which is based on evolutionary principals and aims to keep resistant cells in check by maintaining a population of chemo-sensitive cells.

25 Feb 2016

New study allows researchers to see how insulin in islets responds to sugar

"Scientists and doctors have wanted to know how much insulin a person has in their body, but haven't been able to know the exact amount without the patient being deceased and actually removing the pancreas," says Peter Arvan, division chief of Metabolism, Endocrinology & Diabetes at the University of Michigan.

25 Feb 2016

Blood News and Research

EMA grants Orphan Drug Designation to venetoclax for treatment of acute myeloid leukemia

Out-of-towners using marijuana in Colorado end up in emergency room

Kansas State researchers develop 3-D printed device that quickly detect anemia from blood

Low-sodium intake has little impact on bone health in postmenopausal women

Digital health: the future for medicine?

NUS scientists formulate recipe for making healthier bread

Medical scientists examine potential new tool for helping prevent stroke, heart attack

Ohio State study evaluates trans-catheter interatrial shunt device for diastolic heart failure

Acute mesenteric ischemia can be treated with balloon angioplasty

Neurosurgeons use laser probe to deliver chemotherapy drugs to patients with glioblastoma

New Notre Dame research may lead to a therapy for Niemann-Pick Type C disease

Antidepressant paroxetine suppresses inflammation in people with HIV-related cognitive impairment

Allergan receives FDA approval to market ACZONE (dapsone) Gel, 7.5% for acne treatment

China Biologic's total sales increase by 22.6% in RMB terms to $68.3 million in Q4 2015

Baxalta seeks FDA approval for ADYNOVATE to treat children with hemophilia A and for use in surgical settings

Immune-suppressing drug can improve cognitive ability of patients with schizophrenia

Insulet partners with Mode AGC to develop OmniPod Artificial Pancreas system

Rigel begins fostamatinib Phase 2 trial for treatment of patients with autoimmune hemolytic anemia

Moffitt researchers develop novel therapeutic strategy to keep resistant cells in check

New study allows researchers to see how insulin in islets responds to sugar

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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