Laboratory News and Research

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Discovery might improve design, effectiveness of anti-cancer drugs

Working with an enzyme that degrades anti-cancer drugs in humans, University of North Carolina at Chapel Hill biochemists and colleagues have made a discovery that they believe eventually could help improve such drugs’ design and effectiveness.

18 Oct 2004

Comprehensive study raises questions about "demethylation" agents

Agents believed to selectively "restart" genes that limit cancer's growth -- a potential treatment option already in early clinical studies -- instead turn off as many genes as they turn on, a team of researchers from the National Cancer Institute and Johns Hopkins has discovered.

18 Oct 2004

Benitec receives exclusive rights to use DNA technology pioneered at Stanford University for all RNAi therapeutic uses

Benitec has announced an exclusive licensing deal with Stanford University. Under the license, Benitec receives exclusive rights to use the Minicircle DNA technology pioneered at Stanford University for all RNAi therapeutic uses, with sub-licensing rights.

18 Oct 2004

Cyclopamine, derived from the corn lily may treat and prevent basal cell carcinoma

Researchers at the University of Texas Medical Branch at Galveston (UTMB) have demonstrated in laboratory animals that a compound derived from a common plant can be used to treat and prevent the most widespread form of cancer in people

18 Oct 2004

Collaborative research will help bring hope to Americans who are losing their sight to degenerative retinal diseases

A collaborative research and development agreement signed today between the U.S. Department of Energy (DOE) and Second Sight LLC will help bring hope to hundreds of thousands of Americans who are losing their sight to degenerative retinal diseases.

18 Oct 2004

People who drank alcohol on a regular basis appeared to have less cardiovascular disease

Many previous studies have shown a link between moderate alcohol consumption, versus abstinence or heavy consumption, and decreased mortality from cardiovascular disease.

16 Oct 2004

We are at the very beginning of 'gene finding' for alcohol response

Alcoholism is a complex, genetically influenced disorder. Multiple phenotypes – measurable and/or observable traits or behavior – contribute to the risk of developing alcoholism, particularly disinhibition, alcohol metabolizing patterns, and a low level of response (LR) to alcohol.

16 Oct 2004

Significant steps to fight a deadly childhood muscle cancer

University of Utah scientists have taken significant steps to fight a deadly childhood muscle cancer by identifying some of the genetic events that cause the disease and then engineering mice that develop the tumors.

16 Oct 2004

Single protein appears central to the formation of the long-term memories

Researchers at the National Institute of Child Health and Human Development have discovered that a single protein appears central to the formation of the long-term memories.

16 Oct 2004

Laboratory test of evolutionary theory confirms the importance of connections between populations

Researchers studying the evolutionary dynamics of bacteria and viruses in bubbling glass tubes have confirmed an evolutionary theory of central importance to ecologists studying more familiar flora and fauna in the wild.

13 Oct 2004

PAHO reports on the care and treatment of people with HIV in the Americas

The Pan American Health Organization (PAHO) has issued reports on the first seven of 47 countries and territories with new and specific data on the care and treatment of people with HIV in the Americas.

13 Oct 2004

Wisconsin has identified its first laboratory confirmed case of influenza this season

Public health officials in the department said the case, confirmed by the Wisconsin State Laboratory of Hygiene to be influenza type A (H3 subtype), involves an adult female from Waupaca County.

13 Oct 2004

Research shows brain cells move like a two-stroke engine

Following the often-quoted advice of Yogi Berra — "You can observe a lot by just watching" — Rockefeller University scientists show that nerve cells in the developing brains of humans and other mammals move in a two-part "step" led by a structure within the cell called the centrosome.

13 Oct 2004

Low dose aspirin dosages trigger the body to generate its own anti-inflammatory compounds

Researchers at Brigham and Women’s Hospital (BWH) and colleagues have demonstrated for the first time in humans in a randomized clinical trial that low-dose aspirin - dosages equivalent to one baby aspirin (81 mg) - trigger the body to generate its own anti-inflammatory compounds that help fight unwanted inflammation.

13 Oct 2004

Infections among injecting drug users are a growing public health concern in the UK

New figures published by the UK's Health Protection Agency show that infections among injecting drug users (IDUs) are a growing public health concern.

13 Oct 2004

Options for women experiencing hair loss

Each year, women spend countless hours and dollars on their hair. It can play a major role in a woman’s self-confidence and self-esteem, making female pattern hair loss a potentially debilitating condition, socially and emotionally. But it doesn’t have to be.

13 Oct 2004

Research findings represents a step toward understanding the machinery by which the brain processes decisions

While neurobiologists have long suspected that certain regions of the brain are specifically involved in making decisions, the challenge has been to develop rigorous laboratory behavioral experiments that could pinpoint those areas.

13 Oct 2004

Melanin is not only good for you, it also can be bad

Blondes and redheads not only are more susceptible to skin cancer, but the source of their skin and hair pigmentation, melanin, actually magnifies the damaging effects of ultraviolet (UV) rays, according to a study published online this week in the Proceedings of the National Academy of Sciences.

13 Oct 2004

A new approach to controlling blood cholesterol levels may be a potential treatment for Alzheimer's disease

A new approach to controlling blood cholesterol levels that is already being investigated to prevent cardiovascular disease also may be a potential treatment for Alzheimer's disease.

13 Oct 2004

Technique for genetically modifying blood stem cells brings cure for blood diseases closer

The condition of mice with a genetic blood disease called beta-thalassemia improved significantly following treatment of their blood forming cells with a gene that enabled them to produce the type of hemoglobin normally found only in the fetus.

12 Oct 2004

Laboratory News and Research

Discovery might improve design, effectiveness of anti-cancer drugs

Comprehensive study raises questions about "demethylation" agents

Benitec receives exclusive rights to use DNA technology pioneered at Stanford University for all RNAi therapeutic uses

Cyclopamine, derived from the corn lily may treat and prevent basal cell carcinoma

Collaborative research will help bring hope to Americans who are losing their sight to degenerative retinal diseases

People who drank alcohol on a regular basis appeared to have less cardiovascular disease

We are at the very beginning of 'gene finding' for alcohol response

Significant steps to fight a deadly childhood muscle cancer

Single protein appears central to the formation of the long-term memories

Laboratory test of evolutionary theory confirms the importance of connections between populations

PAHO reports on the care and treatment of people with HIV in the Americas

Wisconsin has identified its first laboratory confirmed case of influenza this season

Research shows brain cells move like a two-stroke engine

Low dose aspirin dosages trigger the body to generate its own anti-inflammatory compounds

Infections among injecting drug users are a growing public health concern in the UK

Options for women experiencing hair loss

Research findings represents a step toward understanding the machinery by which the brain processes decisions

Melanin is not only good for you, it also can be bad

A new approach to controlling blood cholesterol levels may be a potential treatment for Alzheimer's disease

Technique for genetically modifying blood stem cells brings cure for blood diseases closer

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