Laboratory News and Research

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Complete laparoscopic skills training curriculum based entirely in the laboratory

A pilot in training doesn’t fly a plane at his first lesson. And so it goes for surgeons in training. To learn such complex skills, it’s safer and more effective to practice first on a simulator.

29 Sep 2004

Trial shows which brain cancer patients benefit from temozolomide

An international team of scientists and cancer specialists has identified which patients with the deadly form of brain tumours called glioblastomas are likely to live longer if they are treated with temozolomide, and which patients are likely to get only marginal, if any, benefit.

28 Sep 2004

Microfluidics help lab-on-a-chip development skyrocket

Lab-on-a-chip (LOC) development has skyrocketed in the last couple of years due to constant efforts in harnessing microfluidics and µTAS to improve the LOC design and function. The distinct advantages that they bestow on applications are pushing the commercial potential of LOCs.

28 Sep 2004

Research shows specific damage to nervous system in veterans with Gulf War syndrome

UT Southwestern researchers report that damage to the parasympathetic nervous system may account for nearly half of the typical symptoms - including gallbladder disease, unrefreshing sleep, depression, joint pain, chronic diarrhea and sexual dysfunction - that afflict those with Gulf War syndrome. Their findings will be published in the October issue of the American Journal of Medicine and are currently available online.

27 Sep 2004

Researchers have integrated heart cells grown from human embryonic stem cells into a host heart

Researchers at the Technion-Israel Institute of Technology and Rambam Medical Center have demonstrated that heart cells grown from human embryonic stem cells can integrate into the host heart and help regulate its activity, becoming in effect a biological pacemaker.

27 Sep 2004

50,000 women whose sisters had breast cancer needed for nationwide study

Women who know the angry, helpless feeling of watching a sister face breast cancer have gained a new, active, and personal way to fight the disease with the nationwide launch of The Sister Study.

26 Sep 2004

Study is the first to show that lowering the levels of lipid in nerve terminals affects the efficiency of neurotransmission

Yale researchers demonstrate the crucial role of a membrane lipid called phosphatidylinositol-4,5-bisphosphate (PtdIns (4,5)P2) in the communication of information between synapses in the brain, according to a study published this week in Nature.

26 Sep 2004

Researchers have successfully targeted an HIV protein that has eluded existing therapies

Researchers targeted Nef, a protein responsible for accelerating the development of acquired immunodeficiency syndrome, or AIDS. Nef was targeted with small molecules synthesized by the researchers – molecules that disrupted Nef’s interaction with other proteins.

26 Sep 2004

Study presents multiple lines of evidence against the proposed link between SV40 and human mesotheliomas

Mesothelioma is an aggressive cancer of the chest cavity that kills about 2000 people a year in the United States.

26 Sep 2004

Discovery of how protein in teeth controls bone-like crystals to form steely enamel

Bone and enamel start with the same calcium-phosphate crystal building material but end up quite different in structure and physical properties.

26 Sep 2004

Lassa Fever, not seen in US for 15 years re-emerges

The New Jersey Department of Health and Senior Services reported today that a 38-year-old Mercer County man died on August 28 from an acute viral disease called Lassa fever, a condition that is rare in the U.S., but endemic to West Africa.

23 Sep 2004

First generation of human retinal cells in the laboratory from human embryonic stem cells

Some of these retinal tissues such as Retinal Pigment Epithelium (RPE) may provide a novel therapeutic strategy for such devastating diseases as macular degeneration, retinitis pigmentosa, and other retinal degenerative diseases.

23 Sep 2004

Promising lead in developing anti-viral drugs with the potential to fight HIV and HSV

Dr Norelle Daly, from UQ’s Institute for Molecular Bioscience, is looking at the molecular structure of retrocyclin, a molecule with the ability to protect human cells from HIV infection.

23 Sep 2004

Research may lead to alternatives to antibiotic drugs for treating bacterial diseases

UCLA microbiologists report the discovery of a new class of genetic elements, similar to retroviruses, that operate in bacteria, allowing them to diversify their proteins to bind to a large variety of receptors.

23 Sep 2004

Females are predisposed to succumb to the temptation to overeat

It is well known that obesity has reached epidemic proportions. As waistbands expand, so do the number of health gurus heralding the benefits of portion control and exercise to keep obesity at bay.

23 Sep 2004

Potential new way to control drug-resistant bacteria

The researchers, who encountered this genetic property while working on an unrelated project, believe that this discovery could lead to the use of genetically engineered phages to treat bacterial infections that have become resistant to antibiotics.

23 Sep 2004

Four or more glasses of red wine per week may reduce risk of prostate cancer by 50 percent

Drinking a glass of red wine a day may cut a man's risk of prostate cancer in half, and the protective effect appears to be strongest against the most aggressive forms of the disease

23 Sep 2004

A naturally occurring chemical that may repel yellow fever mosquitoes can now be made in the laboratory

Gaur acid is a natural skin secretion of the gaur, an Asian wild ox. Preliminary evidence suggests that this chemical discourages the landing and feeding of Aedes aegypti, a common mosquito that carries and transmits the yellow fever virus in some parts of the world.

23 Sep 2004

Nanowires could be used to sense thousands of different viruses

Harvard University scientists have found that ultra-thin silicon wires can be used to electrically detect the presence of single viruses, in real time, with near-perfect selectivity.

22 Sep 2004

THC in marijuana may block the spread of forms of cancer causing herpes viruses

The compound in marijuana that produces a high, delta-9 tetrahydrocannbinol or THC, may block the spread of several forms of cancer causing herpes viruses, University of South Florida College of Medicine scientists report.

22 Sep 2004

Laboratory News and Research

Complete laparoscopic skills training curriculum based entirely in the laboratory

Trial shows which brain cancer patients benefit from temozolomide

Microfluidics help lab-on-a-chip development skyrocket

Research shows specific damage to nervous system in veterans with Gulf War syndrome

Researchers have integrated heart cells grown from human embryonic stem cells into a host heart

50,000 women whose sisters had breast cancer needed for nationwide study

Study is the first to show that lowering the levels of lipid in nerve terminals affects the efficiency of neurotransmission

Researchers have successfully targeted an HIV protein that has eluded existing therapies

Study presents multiple lines of evidence against the proposed link between SV40 and human mesotheliomas

Discovery of how protein in teeth controls bone-like crystals to form steely enamel

Lassa Fever, not seen in US for 15 years re-emerges

First generation of human retinal cells in the laboratory from human embryonic stem cells

Promising lead in developing anti-viral drugs with the potential to fight HIV and HSV

Research may lead to alternatives to antibiotic drugs for treating bacterial diseases

Females are predisposed to succumb to the temptation to overeat

Potential new way to control drug-resistant bacteria

Four or more glasses of red wine per week may reduce risk of prostate cancer by 50 percent

A naturally occurring chemical that may repel yellow fever mosquitoes can now be made in the laboratory

Nanowires could be used to sense thousands of different viruses

THC in marijuana may block the spread of forms of cancer causing herpes viruses

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Industry Focus eBook - Analytical Chemistry (3rd edition)

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Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo