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Scientists identify origins of anaplastic large cell lymphoma

Anaplastic large cell lymphoma (ALCL) is a very aggressive cancer of the blood, which usually occurs as a tumour in lymph nodes, the skin, the lungs, the liver, and in soft tissue, and mainly affects children and young adults.

18 Jan 2016

Large-scale clinical trial to evaluate dengue vaccine launched in Brazil

A large-scale clinical trial to evaluate whether a candidate vaccine can prevent the mosquito-borne illness dengue fever has been launched in Brazil. The vaccine, TV003, was developed by scientists in the laboratory of Stephen Whitehead, Ph.D., at NIH's National Institute of Allergy and Infectious Diseases (NIAID).

17 Jan 2016

Researchers find association between obesity and VTE in pediatric populations

Researchers at Wake Forest Baptist Medical Center have found an association between obesity and the formation of blood clots in the veins of children and adolescents.

17 Jan 2016

Troponin T test provides possible one hour diagnosis of heart attack

Results from the TRAPID-AMI clinical study have been published online by the Annals of Emergency Medicine, confirming a novel approach for a more rapid diagnosis of heart attack in patients with acute chest pain.

From Roche Sequencing and Life Science 15 Jan 2016

NHS Organ Donor Register failing transplant patients

The organs of over 500 individuals who had stated their wish for their organs to be used in transplants, and were included on the NHS Organ Donor Register, could not be used after relatives refused to allow organ donation.

15 Jan 2016

Help beat the blues this Monday with a B12 Boost

Boost your mood and energy levels this Blue Monday (18 January) by topping up your vitamin B12, say natural health pioneers BetterYou.

From BetterYou Ltd 14 Jan 2016

Determining Ectopeptidase Activity: An Interview with Professor Stephen Weber, University of Pittsburgh

The scope of the activity of neuropeptides is remarkably broad. For example, neuropeptides are involved in pain control, mood/depression/eating disorders, social and emotional behaviour, body weight, drug abuse, stress, reproduction, motor control, memory, and in maintaining neuronal health when they are stressed.

From Pittcon 14 Jan 2016

IQWiG finds no added benefit for pomalidomide drug in multiple myeloma

Pomalidomide (trade name: Imnovid) has been approved since 2013 for the treatment of multiple myeloma that has returned and is difficult to treat. The drug is an option for adults who have received two or more prior treatment regimens, including treatment with the drugs lenalidomide and bortezomib, and in whom the last treatment had no sufficient effect.

13 Jan 2016

Simple paper test could confirm presence of illnesses even before patients feel symptoms

A multi-disciplinary team of researchers has developed a new diagnostic test that can change the medical landscape by making it possible for patients to quickly determine if they are infected with an illness, using a simple paper test sensitive enough to detect markers of various illnesses using minute amounts of blood, sweat, or other biological material.

13 Jan 2016

First patient enrolled in ThromboGenics' Phase II CIRCLE study of ocriplasmin in NPDR patients

ThromboGenics NV, an integrated biopharmaceutical company focused on developing and commercializing innovative treatments for diabetic eye disease, today announces that the first patient has been enrolled in its Phase II CIRCLE study evaluating the efficacy and safety of multiple doses of ocriplasmin in inducing total posterior vitreous detachment (PVD) in patients with non-proliferative diabetic retinopathy (NPDR).

13 Jan 2016

Selenium supplementation may have positive and negative effects on immune system

A more thorough evaluation of selenium supplementation is needed, to better understand its benefits to our immune system, and the risks.

13 Jan 2016

Middle-aged patients undergoing AVR may fare better with tissue-based valves rather than metal-based valves

Patients between the ages of 40 and 70 who undergo aortic valve replacement (AVR) may fare better with tissue-based valves rather than metal-based valves, according to a review article posted online today by The Annals of Thoracic Surgery.

13 Jan 2016

Inflammation associated with elevated glutamate in the brain could guide depression treatments

Psychiatrists investigating depression have been energized in recent years by reports of rapid, successful treatment with drugs that interfere with the brain chemical glutamate, such as the anesthetic ketamine.

13 Jan 2016

Cornell researchers identify potent cancer-killing proteins that can kill tumors in bloodstream

Cornell researchers have discovered potent cancer-killing proteins that can travel by white blood cells to kill tumors in the bloodstream of mice with metastatic prostate cancer. The breakthrough study will be published Feb. 10 as the cover article in the Journal of Controlled Release.

13 Jan 2016

Sedentary behavior associated with poor cardiovascular health, diabetes in people with severe obesity

Sedentary behavior is associated with poor cardiovascular health and diabetes in adults with severe obesity, independent of how much exercise they perform, a University of Pittsburgh Graduate School of Public Health-led study showed for the first time.

13 Jan 2016

High doses of vitamin D may increase risk of falls

According to new research summarized by California Pacific Medical Center Research Institute senior scientist Steven Cummings, MD, and colleagues at the University of California, San Francisco and Harvard Medical School, contrary to common beliefs, relatively high doses of vitamin D may increase the risk of falls.

13 Jan 2016

New mechanism of differentiation may offer novel therapeutic approaches to blood malignancies, solid tumors

In humans the differentiation of stem cells into hundreds of specialized cell types is vital. Differentiation drives development from fertilized egg to a newborn, and it underlies the continuous replacement of the 5 billion cells that die every hour in an adult. On the downside, mutations in differentiation pathways of different cell types can be drivers of cancers.

13 Jan 2016

Young children in deep poverty fare worse on health and development indicators

Young children in deep poverty, whose family income is below 50 percent of the federal poverty line, fare even worse on health and development indicators than children in poverty, according to a study released by the National Center for Children in Poverty at Columbia University's Mailman School of Public Health.

12 Jan 2016

Pre-existing nutritional deficits, immune dysfunction may increase hepatitis E risk during pregnancy

Researchers from the Johns Hopkins Bloomberg School of Public Health have found a link between pre-existing nutritional deficits and immune dysfunction and the risk of hepatitis E infection during pregnancy.

12 Jan 2016

Researchers discover molecular target for DNA repair defects behind Fanconi anemia

Researchers have identified a molecular target and experimental treatment strategy for DNA repair defects behind Fanconi anemia – a complex genetic disorder responsible for birth anomalies, organ damage, anemia and cancer.

12 Jan 2016

Blood News and Research

Scientists identify origins of anaplastic large cell lymphoma

Large-scale clinical trial to evaluate dengue vaccine launched in Brazil

Researchers find association between obesity and VTE in pediatric populations

Troponin T test provides possible one hour diagnosis of heart attack

NHS Organ Donor Register failing transplant patients

Help beat the blues this Monday with a B12 Boost

Determining Ectopeptidase Activity: An Interview with Professor Stephen Weber, University of Pittsburgh

IQWiG finds no added benefit for pomalidomide drug in multiple myeloma

Simple paper test could confirm presence of illnesses even before patients feel symptoms

First patient enrolled in ThromboGenics' Phase II CIRCLE study of ocriplasmin in NPDR patients

Selenium supplementation may have positive and negative effects on immune system

Middle-aged patients undergoing AVR may fare better with tissue-based valves rather than metal-based valves

Inflammation associated with elevated glutamate in the brain could guide depression treatments

Cornell researchers identify potent cancer-killing proteins that can kill tumors in bloodstream

Sedentary behavior associated with poor cardiovascular health, diabetes in people with severe obesity

High doses of vitamin D may increase risk of falls

New mechanism of differentiation may offer novel therapeutic approaches to blood malignancies, solid tumors

Young children in deep poverty fare worse on health and development indicators

Pre-existing nutritional deficits, immune dysfunction may increase hepatitis E risk during pregnancy

Researchers discover molecular target for DNA repair defects behind Fanconi anemia

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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