Analgesia News and Research

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UQ's new research center aims to improve lives of people living with pain

One of the world's foremost pain experts has highlighted the risks of bypassing established processes for assessing the safety and effectiveness of medicines at the launch of a research center at the University of Queensland.

10 Apr 2025

Coaxial silicone drains reduce pain after VATS lobectomy without compromising efficacy

Chest drains are routinely used after video-assisted thoracoscopic surgery (VATS) lung resections to evacuate fluid and air from the pleural space.

10 Apr 2025

Rubber hand illusion can decrease pain intensity

Researchers conducted an experiment in which test subjects felt like a rubber hand was part of their own body. As a result, their own hand became less sensitive to pain.

18 Mar 2025

Strong synthetic opioids linked to poor postoperative pain experience

The use of powerful synthetic opioids, such as sufentanil and remifentanil, during surgery is linked to a subsequent poor 'pain experience'---a composite of emotional, cognitive, and physical aspects of pain- suggests research published in the open access journal Regional Anesthesia & Pain Medicine.

26 Feb 2025

Menarini Group signs licensing deal with Insilico for promising cancer treatment

The Menarini Group ("Menarini"), a leading international pharmaceutical and diagnostics company, and Stemline Therapeutics, Inc. ("Stemline"), a wholly-owned subsidiary of the Menarini Group focused on bringing transformational oncology treatments to cancer patients, and Insilico Medicine ("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, today announced that the companies have entered into an exclusive licensing agreement granting Stemline the global rights to develop and commercialize a preclinical small molecule targeting high unmet needs in oncology.

10 Jan 2025

Study offers a potential pathway for safer, non-addictive pain management

Researchers from the National University of Singapore (NUS), in collaboration with Peking University, China, have made a discovery regarding the TRPV1 (transient receptor potential vanilloid 1) ion channel and its role in pain perception.

11 Dec 2024

Boosting endocannabinoids could reduce opioid addiction risk

Increasing the levels of chemicals naturally produced in the body called endocannabinoids may thwart the highly addictive nature of opioids such as morphine and oxycodone while maintaining the drugs' ability to relieve pain, according to Weill Cornell Medicine investigators working with researchers from The Center for Youth Mental Health at NewYork-Presbyterian.

2 Dec 2024

Study reveals racial bias in postsurgical analgesia

While recovering from major surgery, Black patients may be less likely to receive certain multimodal analgesia options and more likely to receive oral opioids than white patients, according to research being presented at the ANESTHESIOLOGY® 2024 annual meeting.

21 Oct 2024

It's official! Men and women experience and manage pain differently

Researchers uncover sex-specific pain management mechanisms, revealing men rely on endogenous opioids while women use alternative pathways for pain relief.

21 Oct 2024

Advancements in AI-driven sensors transform pain management

A review paper by scientists at the Indiana University Bloomington summarized recent engineering eﬀorts in developing various sensors and devices for addressing challenges in the personalized treatment of pain.

27 Sep 2024

Study highlights inequities in emergency care for unintentional ingestions in children

Unintentional injuries like falls, drownings and poisonings are the leading cause of death in patients ages 1-4, and a significant portion of these deaths are linked to unintentional ingestions - such as swallowing a drug or poison.

27 Sep 2024

New study challenges dopamine's role in placebo effects and pain relief

New findings argue against a direct causal role for dopamine during the experience of a treatment effect in the establishment of positive treatment expectations and placebo analgesia in healthy volunteers, according to a study published September 24th in the open-access journal PLOS Biology by Ulrike Bingel from University Hospital Essen, Germany, and colleagues.

24 Sep 2024

Study finds flurbiprofen ester effective for pain relief during transvaginal 4D hysterosalpingography

Announcing a new article publication for BIO Integration journal. The purpose of this study was to determine the analgesic effect of a flurbiprofen ester injection via continuous intravenous drip during transvaginal 4-dimensional hysterosalpingography (TVS 4D-HyCoSy).

25 Jul 2024

Study: Iron infusions superior to blood transfusions for surgical patients with anemia

In a rigorous medical records study covering tens of thousands of patients, Johns Hopkins Medicine researchers conclude that some patients with preoperative anemia have better outcomes if they get iron infusions before surgery rather than standard red blood cell transfusions.

25 Jul 2024

Neuroscientists discover a key piece of the placebo effect puzzle

The placebo effect is very real. This we've known for decades, as seen in real-life observations and the best double-blinded randomized clinical trials researchers have devised for many diseases and conditions, especially pain.

24 Jul 2024

New brain targets for GLP1-based obesity drugs may reduce weight without nausea

Researchers identified distinct hindbrain GLP1R neurons driving satiety and aversion, offering new targets for effective, side-effect-free obesity treatments.

14 Jul 2024

UCLA study finds insomnia drug suvorexant prevents opioid addiction in mice

New research led by UCLA Health has found a drug that treats insomnia works to prevent the addictive effects of the morphine opioids in mice while still providing effective pain relief.

9 Jul 2024

Labor epidurals linked to lower risk of severe maternal morbidity

Having an epidural during labor is associated with a marked reduction in serious complications in the first few weeks after giving birth, finds a study published by The BMJ today.

22 May 2024

Esketamine after childbirth cuts risk of postnatal depression by three-quarters

Low-dose esketamine administered post-labor significantly reduced depressive symptoms in women with prenatal depression within 42 days, despite an increase in short-lived neuropsychiatric side effects.

14 Apr 2024

Study links social inequality to lower pain relief during labor

In a study of women in labor in the U. S., social inequity was associated with lower use of neuraxial analgesia -- an epidural or spinal pain reliever-- among non-Hispanic White women and, to a greater extent, among African American women, according to research at Columbia University Mailman School of Public Health and Columbia Vagelos College of Physicians and Surgeons (P&S).

2 Feb 2024