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Mount Sinai researchers identify the structure of a special red blood cell transporter

Researchers at the Icahn School of Medicine at Mount Sinai have identified the structure of a special transporter found in red blood cells and how it interacts with drugs.

8 Sep 2023

CBD and THC: promising remedies for aluminum-related neurological damage

Researchers assessed the protective effect of CBD and THC oils against aluminum toxicity.

20 Jun 2023

Experts identify a novel fucosylated heparan sulfate from the midgut gland of the Japanese scallop

Glycosaminoglycans (GAGs), including chondroitin sulfate (CS), heparan sulfate (HS), heparin, and hyaluronan are linear and acidic polysaccharides found in the extracellular matrix of all animal tissues. GAGs are widely used as functional ingredients in health products, pharmaceuticals, and cosmetics, and are prepared from biological samples such as shark cartilage and porcine intestinal mucosa. Consequently, the demand for new sources of GAGs is ever-present. For example, the supply source of the anticoagulant heparin - generally prepared from porcine intestinal mucosa in China - was threatened by African swine fever in 2018.

15 Jun 2023

To what extent does prenatal folate status modify associations between early pregnancy perfluoroalkyl and polyfluoroalkyl substance exposure and birth outcomes?

Researchers evaluated the relationship between PFAS exposure during pregnancy and birth outcomes.

2 Jun 2023

High-fat diets' eye-opening impact: Study reveals link to retinal damage and bisretinoid accumulation

In this study, the effects of a high-fat diet on the formation of bisretinoids in photoreceptor cells were explored. The results showed that mice on a high-fat diet had increased levels of bisretinoids and retinol-binding protein 4, which are associated with metabolic dysregulation.

8 May 2023

Researchers elucidate how a single mutation causes episodic ataxia type 6

Worldwide, only a handful of patients are known to suffer from episodic ataxia type 6, a neurological disease that causes transient loss of muscle control.

3 Apr 2023

Study may pave way for a more nuanced understanding of taste perception

Humans perceive five basic taste sensations: sweet, umami, bitter, salty, and sour. Specific foods trigger taste recognition of these sensations through the activation of different receptors in our taste buds.

23 Mar 2023

Understanding the structure of CFTR could help design more effective therapies for cystic fibrosis

Scientists at St. Jude Children's Research Hospital and Rockefeller University have combined their expertise to gain a better understanding of the cystic fibrosis transmembrane conductance regulator (CFTR).

23 Mar 2023

The immunometabolic regulatory mechanisms for the pathogenesis of COVID-19

A new study aimed to analyze the immunometalobism BALF cells from mild to severe COVID-19 patients using computational algorithms that quantified metabolic fluxes and metabolic pathways.

13 Oct 2022

The risk of adverse reactions when herbal medications are taken with cancer drugs

A new study discusses phytovigilance initiatives based on the real-world use of herbal drugs in cancer along with conventional chemotherapy.

24 Aug 2022

Study tests equine polyclonal antibodies against SARS-CoV-2 variants

A recent study published tested equine polyclonal antibodies against SARS-CoV-2.

8 Aug 2022

Probenecid shows activity against respiratory syncytial virus

A new study describes the antiviral activity of the approved drug probenecid against respiratory syncytial virus.

29 Apr 2022

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated the potent neutralizing ability of a polyclonal equine antibody (Ab), FBR-002, against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs), including Omicron.

28 Feb 2022

Anion News and Research

Mount Sinai researchers identify the structure of a special red blood cell transporter

CBD and THC: promising remedies for aluminum-related neurological damage

Experts identify a novel fucosylated heparan sulfate from the midgut gland of the Japanese scallop

To what extent does prenatal folate status modify associations between early pregnancy perfluoroalkyl and polyfluoroalkyl substance exposure and birth outcomes?

High-fat diets' eye-opening impact: Study reveals link to retinal damage and bisretinoid accumulation

Researchers elucidate how a single mutation causes episodic ataxia type 6

Study may pave way for a more nuanced understanding of taste perception

Understanding the structure of CFTR could help design more effective therapies for cystic fibrosis

The immunometabolic regulatory mechanisms for the pathogenesis of COVID-19

The risk of adverse reactions when herbal medications are taken with cancer drugs

Study tests equine polyclonal antibodies against SARS-CoV-2 variants

Probenecid shows activity against respiratory syncytial virus

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

Study reports of receptor-binding domain multimer capable of enhancing the immune response against SARS-CoV-2

Study suggests algal polysaccharide may be a promising anti-COVID-19 candidate

Green seaweed extract exhibits anti-SARS-CoV-2 activity in vitro

Using self-assembled drugs to achieve a breakthrough in cancer therapy

Nitrogen-doped fluorescent carbon dots for detecting iodide ion, curcumin in biological and food samples

Study paves the way to a new drug design concept

Enterprise Therapeutics doses first subjects in Phase I trial for novel cystic fibrosis therapy ETD001

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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