Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Skull bone marrow contains immune hubs that fight brain cancer

Researchers at Washington University School of Medicine in St. Louis have discovered lymph node-like structures in the skull bone marrow of mice for the first time and demonstrated that they act as rapid first responders against brain cancer before distant lymph nodes get the signal that abnormal cells are present.

19 Aug 2026

$Muscle cells play a vital role in repairing fractured bones$

Muscle cells play a vital role in repairing fractured bones

Bone healing is a complex process that depends on the coordinated activity of many different cell types.

14 Aug 2026

Würzburg researchers discover alternative approach to preventing thrombosis

Glycoprotein VI, or GPVI for short, is a surface receptor found exclusively on platelets and their precursor cells, megakaryocytes in the bone marrow.

14 Aug 2026

Coral-inspired scaffold enhances bone repair by reprogramming immune cells

SONFH is one of the leading causes of non-traumatic osteonecrosis. Reported in up to 9%–40% of patients receiving prolonged or high-dose glucocorticoid therapy, the condition progressively weakens the femoral head and can eventually lead to joint collapse, making effective bone repair a major clinical challenge.

13 Aug 2026

New study uncovers metabolic vulnerability in high-risk myelodysplastic syndromes

Researchers at the University of Colorado Anschutz Cancer Center have identified a previously unknown metabolic weakness in the stem cells that drive high-risk myelodysplastic syndromes (MDS), a discovery that could lead to more targeted treatments for this aggressive blood cancer.

10 Aug 2026

New gene signature predicts immunotherapy success for bone marrow cancers

A team led by researchers from the German Cancer Research Center (DKFZ), the HI-STEM Stem Cell Institute, and Medical Clinic V at Heidelberg University Hospital (UKHD) has characterized T cells in the bone marrow in cases of multiple myeloma and acute myeloid leukemia: A specific group of tumor-reactive T cells can recognize and, in principle, fight cancer cells, but is often not sufficiently activated.

10 Aug 2026

Scientists map key differences in stem cell potency for treating knee osteoarthritis

Knee osteoarthritis (KOA) affects more than 1 in 10 people over 40 years of age, impairing patients' mobility and quality of life.

7 Aug 2026

New study reveals genetic drivers of inherited bone marrow failure syndrome

Inherited bone marrow failure syndrome, or IBMFS, describes a group of disorders in which inherited genetic abnormalities impair the bone marrow's ability to produce sufficient healthy blood cells.

6 Aug 2026

Scalable education program protects transplant survivors from elevated skin cancer risk

Experts at City of Hope, one of the nation's largest and most advanced cancer research and treatment organizations, are shining a spotlight on the risk of skin cancer faced by hematopoietic cell transplant (HCT) survivors, as well as the need for early detection.

6 Aug 2026

Risk-adapted frameworks reshape pediatric neuroblastoma care

Neuroblastoma is the most common solid tumor outside the brain in children younger than five years old and accounts for about 15% of pediatric cancer deaths.

6 Aug 2026

Researchers map how blood cells cross into the brain during aging

The brain's immune system has long been thought to exist independently from the rest of the body, complete with its own specialized immune cells and a blood-brain barrier that limits what can travel into the brain.

6 Aug 2026

Malaria infection causes permanent damage to the spleen immune cells

Macrophages formed in the bone marrow can only assume the function of embryonal phagocytes, or "scavenger cells," to a certain degree according to a study by the University of Bonn and the Peter Doherty Institute for Infection and Immunity at the University of Melbourne.

4 Aug 2026

Child-friendly lung test identifies subtle abnormalities before stem cell transplant

As spirometry requires coordinated deep breathing and can be challenging for children to perform, researchers from the USA, as part of the TRANSPIRE study investigating lung complications in children undergoing hematopoietic stem cell transplantation (HSCT), explored the potential of oscillometry, a simple and child-friendly lung function test.

3 Aug 2026

QUANTUM trial tests immune-targeting approach for primary plasma cell leukemia

The Alliance for Clinical Trials in Oncology today announced the activation of The QUANTUM Trial (Alliance A062401), a clinical study designed to test a novel, immune-targeting approach for patients newly diagnosed with primary plasma cell leukemia (PCL).

30 Jul 2026

Medical breakthrough allows kidney transplant for patient with zero options

An international research team led by the Medical University of Vienna reports on a new treatment strategy that has made a kidney transplant possible for a patient with no realistic chance of receiving a suitable donor organ.

30 Jul 2026

Study reveals how gum disease drives systemic inflammation

A recent study revealed that periodontitis reprograms bone marrow neutrophils through a Chac2-driven glutathione metabolic pathway, promoting a highly inflammatory N1 state that fuels systemic inflammation.

28 Jul 2026

Landmark study identifies new genetic risk factors linked to fibromyalgia syndrome

In a landmark study published in Nature Medicine, an international team of researchers has identified new genetic risk factors associated with fibromyalgia syndrome.

28 Jul 2026

Too little or too much iodine may push immunity off balance

This narrative review finds that adequate iodine supports thyroid hormone signaling, leukocyte metabolism, antioxidant defenses, and antimicrobial activity in humans and domesticated mammals. Both deficiency and sustained excess may impair immunity or promote thyroid inflammation, but precise immune-specific intake thresholds remain uncertain.

27 Jul 2026

Iowa State study identifies potential new target for leukemia treatment

In leukemia's most aggressive forms, the blood cell factories in our bone marrow falter. Instead of dividing and multiplying at their usual prolific pace, generating hundreds of billions of new cells daily, some precursor cells stall out at an immature stage.

24 Jul 2026

Thymulin curbs age-related inflammation and slows breast tumors in mice

Thymulin reduced age-associated inflammatory myeloid cells and slowed breast-tumor growth in aged mice by suppressing NF-κB signaling. The peptide also restored anti-PD-L1 responsiveness in aged mouse models, while human cell and tumor data supported an age-linked inflammatory myeloid profile.

23 Jul 2026