Microscopy News and Research

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Scientists map step-by-step activation of brain receptors

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, know that even slight changes in their activity level can mean the difference between normal function and serious neurological disorders.

24 Sep 2025

UNM researcher develops new model for characterizing different forms of vascular dementia

Vascular dementia - cognitive impairment caused by disease in the brain's small blood vessels - is a widespread problem, but it has not been as thoroughly studied as Alzheimer's disease, in which abnormal plaques and protein tangles are deposited in neural tissue.

19 Sep 2025

New research links postictal symptoms in epilepsy to hidden brain waves

In everyday clinical practice, symptoms are regularly observed after epileptic seizures, known as "post-ictal symptoms", which, in contrast to the usually short duration of seizures, typically last several minutes to hours. Besides symptoms such as impaired speech and language comprehension, a state of disorientation may occur.

19 Sep 2025

Researchers identify seizure-associated depolarization as cause of post-ictal symptoms

People with temporal lobe epilepsy in particular often wander around aimlessly and unconsciously after a seizure. Researchers at the University Hospital Bonn (UKB), the University of Bonn, and the German Center for Neurodegenerative Diseases (DZNE) have identified a neurobiological mechanism that could be responsible for this so-called post-ictal wandering and potentially other postictal symptoms.

18 Sep 2025

New research positions the placenta at the center of human neurodevelopment and evolution

In a Genomic Press Interview published today in Brain Medicine, Dr. Alex Tsompanidis highlights an exciting new idea that positions the placenta at the center of human neurodevelopment and evolution, challenging conventional wisdom about the origins of autism and human cognition.

16 Sep 2025

Cryo-EM reveals how blood clotting proteins fit together to trigger clot formation

If you've ever accidentally sliced yourself on a broken glass or a piece of paper, you may have noticed that the bleeding can be hard to stop.

13 Sep 2025

Texas Tech research team earns $3 million renewal to advance stroke therapy

Stroke research aims to understand the brain's self-protective and repair mechanisms. Gaining detailed insight into these mechanisms is crucial as such knowledge could lead to newly developed medications and interventions which mimic or engage the brain's self-protective/repair mechanisms, leading to innovative stroke therapies.

13 Sep 2025

Novel method accurately identifies therapeutic antibodies to treat infectious diseases

Scientists at Scripps Research have developed a novel method that uses artificial intelligence (AI) and advanced imaging techniques to more accurately and efficiently identify therapeutic antibodies to treat infectious diseases.

10 Sep 2025

'Resistin like molecule gamma' punches holes into heart cells after myocardial infarction

Nina Kumowski, MD, of the Department of Radiology and Center for Systems Biology at Massachusetts General Hospital, is the lead author and Matthias Nahrendorf, MD, PhD of the Department of Radiology and Center for Systems Biology at MGH, is the senior author of a paper published in Science, "Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia."

9 Sep 2025

Spaceflight accelerates aging of human blood stem cells

Researchers from University of California San Diego Sanford Stem Cell Institute have discovered that spaceflight accelerates the aging of human hematopoietic stem and progenitor cells (HSPCs), which are vital for blood and immune system health.

4 Sep 2025

Auburn researchers uncover staph’s superglue-like grip on human skin

Imagine a child with eczema who scratches a patch of irritated skin. A tiny opening forms, invisible to the eye.

4 Sep 2025

Smell loss emerges as the early behavioural sign of Alzheimer’s

Research reveals immune cells target brainstem nerves, linking smell loss to early Alzheimer's, offering potential for earlier diagnosis and intervention.

4 Sep 2025

Study reveals how type 2 diabetes directly alters the heart’s structure and energy systems

A new study from the University of Sydney has revealed how type 2 diabetes directly alters the heart’s structure and energy systems, offering vital insights into why people with diabetes are at greater risk of heart failure.

2 Sep 2025

Why metformin could protect the brain by rewiring mitochondria

Metformin boosts human oligodendrocyte differentiation and myelination across stem-cell, organoid, and chimera models. The study links these effects to mitochondrial metabolic shifts, supporting its potential as a therapy for multiple sclerosis.

1 Sep 2025

Visualizing lipid transport inside living cells with fluorescence microscopy

Lipid molecules, or fats, are crucial to all forms of life. Cells need lipids to build membranes, separate and organize biochemical reactions, store energy, and transmit information.

29 Aug 2025

Clonogenic hepatocytes identified as engines of liver development

In a new study published in the Journal of Hepatology, researchers from the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) show that only 15–20% of hepatocytes in newborn mice - dubbed clonogenic hepatocytes - are responsible for generating over 90% of the adult liver mass.

29 Aug 2025

New method detects sepsis infections in just two hours

A new diagnostic method would confirm sepsis infections earlier, cutting critical hours in the "race against time" to save patients' lives.

28 Aug 2025

First comprehensive road map shows how the ovarian reserve forms in primates

UCLA scientists have developed the first comprehensive road map showing how the ovarian reserve forms in primates, providing crucial insights into women's health that could revolutionize treatments for infertility and hormonal disorders such as polycystic ovary syndrome, or PCOS.

26 Aug 2025

Innovative cryo-microscopy offers precise views of rapid cell activity

Optical microscopy is a key technique for understanding dynamic biological processes in cells, but observing these high-speed cellular dynamics accurately, at high spatial resolution, has long been a formidable task.

25 Aug 2025

AI and advanced microscopy reveal tangled DNA structures with nanometer precision

At school, it's often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA molecules.

22 Aug 2025

Microscopy News and Research

Scientists map step-by-step activation of brain receptors

UNM researcher develops new model for characterizing different forms of vascular dementia

New research links postictal symptoms in epilepsy to hidden brain waves

Researchers identify seizure-associated depolarization as cause of post-ictal symptoms

New research positions the placenta at the center of human neurodevelopment and evolution

Cryo-EM reveals how blood clotting proteins fit together to trigger clot formation

Texas Tech research team earns $3 million renewal to advance stroke therapy

Novel method accurately identifies therapeutic antibodies to treat infectious diseases

'Resistin like molecule gamma' punches holes into heart cells after myocardial infarction

Spaceflight accelerates aging of human blood stem cells

Auburn researchers uncover staph’s superglue-like grip on human skin

Smell loss emerges as the early behavioural sign of Alzheimer’s

Study reveals how type 2 diabetes directly alters the heart’s structure and energy systems

Why metformin could protect the brain by rewiring mitochondria

Visualizing lipid transport inside living cells with fluorescence microscopy

Clonogenic hepatocytes identified as engines of liver development

New method detects sepsis infections in just two hours

First comprehensive road map shows how the ovarian reserve forms in primates

Innovative cryo-microscopy offers precise views of rapid cell activity

AI and advanced microscopy reveal tangled DNA structures with nanometer precision

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